ChemicalBook > CAS DataBase List > 3-AMINO-5-HYDROXYMETHYLPYRIDINE

3-AMINO-5-HYDROXYMETHYLPYRIDINE

Product Name
3-AMINO-5-HYDROXYMETHYLPYRIDINE
CAS No.
443649-18-1
Chemical Name
3-AMINO-5-HYDROXYMETHYLPYRIDINE
Synonyms
(5-amino-3-pyridyl)methanol;3-PyridineMethanol,5-aMino-;(5-Aminopyridin-3-yl)methanol;3-AMINO-5-HYDROXYMETHYLPYRIDINE;3-Pyridinemethanol,5-amino-(9CI);5-Amino-3-(Hydroxymethyl)Pyridine;3-Amino-5-hydroxymethylpyridine ,97%;3-AMINO-5-HYDROXYMETHYLPYRIDINE ISO 9001：2015 REACH
CBNumber
CB0482943
Molecular Formula
C6H8N2O
Formula Weight
124.14
MOL File
443649-18-1.mol
More
Less

3-AMINO-5-HYDROXYMETHYLPYRIDINE Property

Boiling point:
367.2±27.0 °C(Predicted)
Density 
1.257
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
pka
13.61±0.10(Predicted)
Appearance
White to yellow Solid
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38
Safety Statements 
26
HS Code 
29339900
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TRC
Product number
A630050
Product name
(5-Aminopyridin-3-yl)methanol
Packaging
500mg
Price
$265
Updated
2021/12/16
AK Scientific
Product number
Z2689
Product name
3-Amino-5-hydroxymethylpyridine
Packaging
1g
Price
$286
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA142764
Product name
(5-Aminopyridin-3-yl)methanol
Packaging
2g
Price
$369
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA142764
Product name
(5-Aminopyridin-3-yl)methanol
Packaging
250mg
Price
$70
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
JK172022
Product name
3-Amino-5-hydroxymethylpyridine
Purity
97%
Packaging
250mg
Price
$71
Updated
2021/12/16
More
Less

3-AMINO-5-HYDROXYMETHYLPYRIDINE Chemical Properties,Usage,Production

Chemical Properties

White to light yellow solid

Synthesis

36052-25-2

443649-18-1

General procedure for the synthesis of 5-aminopyridine-3-methanol from 5-aminopyridine-3-carboxylic acid methyl ester: 5-aminopyridine-3-carboxylic acid methyl ester (5.7 g, 30.2 mmol) was dissolved in tetrahydrofuran (THF, 150 mL) and lithium aluminum hydroxide (LiAlH4, 1 M THF solution, 133 mL, 133 mmol) was added slowly at 0 °C. The reaction mixture was stirred at room temperature for 21 hours. Upon completion of the reaction, the reaction mixture was quenched with dilute hydrochloric acid (HCl) and acidified to pH 3, followed by alkalization with solid sodium carbonate (Na2CO3) to pH 8. The solvent was removed by distillation under reduced pressure. The residue was purified by silica gel column chromatography using 20% methanol (MeOH)/dichloromethane (DCM) as eluent to afford the target product 5-aminopyridine-3-methanol (3.8 g, 100% yield), which was analyzed by liquid chromatography coupled with mass spectrometry (LCMS) showing a purity of 97% with a mass-to-charge ratio (m/z) of 125 [M+H]+ and the detector was an evaporative light scattering detector (ELS).

References

[1] Patent: WO2006/117549, 2006, A1. Location in patent: Page/Page column 97
[2] Chemistry - A European Journal, 2002, vol. 8, # 5, p. 1218 - 1226
[3] Bioorganic and Medicinal Chemistry, 2010, vol. 18, # 17, p. 6340 - 6350
[4] Patent: WO2018/13774, 2018, A1. Location in patent: Page/Page column 256; 257

3-AMINO-5-HYDROXYMETHYLPYRIDINE Preparation Products And Raw materials

Raw materials

5-Aminonicotinic acid Tetrahydrofuran Diethyl ether Lithium Aluminum Hydride Methanol Thionyl chloride

Preparation Products

More
Less

3-AMINO-5-HYDROXYMETHYLPYRIDINE Suppliers

China 57 Europe 1 Germany 1 India 1 United Kingdom 3 United States 11 Global 74
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
PharmaBlock Sciences (Nanjing),Inc.
Tel
025-86918202 4000255188
Fax
86-025-86918232
Email
sales@pharmablock.com
Country
China
ProdList
5000
Advantage
55
Nanjing Habo Medical Technology Co., Ltd.
Tel
025-85760892 13376080562
Fax
025-85766769
Email
sales@habotech.com
Country
China
ProdList
884
Advantage
60
Chiba Pharmaceutical Science and technology Co, Ltd.
Tel
0531-81313138 13066006660
Fax
QQ: 3366077777
Email
chibapharm@foxmail.com
Country
China
ProdList
3991
Advantage
55
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12346
Advantage
58
ChengDu TongChuangYuan Pharmaceutical Co.Ltd
Tel
028-83379370 13880556291
Fax
028-87747383
Email
tcy@tcypharm.com
Country
China
ProdList
7218
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Biokitchen
Tel
021-021-021-31663258 13795219287
Fax
021-31663258
Email
donghuanwen@126.com
Country
China
ProdList
8816
Advantage
58
Sichuan BaiPeng Biotechnology Co., Ltd.
Tel
028-65791793 18140026355
Fax
QQ568470422
Email
568470422@qq.com
Country
China
ProdList
9997
Advantage
58
Aikon International Limited
Tel
025-66113011 13155353615
Fax
(7)02557626880
Email
qzhang@aikonchem.com
Country
China
ProdList
15394
Advantage
58
Shanghai WangFa Chemical Technology Co., Ltd.
Tel
13918479294
Fax
-
Email
xiebenfa@163.com
Country
China
ProdList
4087
Advantage
58
Jinan chemkey pharmaceutical Co., Ltd.
Tel
15610156652
Email
baimingshi@163.com
Country
China
ProdList
981
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52687
Advantage
58
Guangdong wengjiang Chemical Reagent Co., Ltd.
Tel
0751-2815688 13927872512
Fax
0751-8963795
Email
3007421951@qq.com
Country
China
ProdList
9939
Advantage
58
Suzhou Rovathin Foreign Trade Co.,Ltd
Tel
0512-65816829 18662214788
Fax
0512-65816829
Email
info@rovathin.com.cn
Country
China
ProdList
9987
Advantage
58
ANHUI WITOP BIOTECH CO., LTD
Tel
+8615255079626
Email
eric@witopchemical.com
Country
China
ProdList
23541
Advantage
58
Blocksynth Pharmaceutical Technology Co.,Ltd
Tel
0086-19817745290; +8619817745290
Email
bd@blocksynth.com
Country
China
ProdList
5661
Advantage
58
Hefei TNJ Chemical Industry Co.,Ltd.
Tel
+86-0551-65418684 +8618949823763
Fax
0086-551-65418684
Email
sales@tnjchem.com
Country
China
ProdList
25356
Advantage
58
Dayang Chem (Hangzhou) Co.,Ltd.
Tel
+86-0571-88938639 +8617705817739
Fax
+86-571-88938652，+86-571- 88492614
Email
info@dycnchem.com
Country
China
ProdList
52846
Advantage
58
Hefei Hirisun Pharmatech Co., Ltd
Tel
+8615056975894
Fax
86-0551-62678551
Email
shawn@hirisunpharm.com
Country
CHINA
ProdList
9911
Advantage
58
Shaanxi Dideu Medichem Co. Ltd
Tel
+86-029-89586680 +86-18192503167
Fax
+86-29-88380327
Email
1026@dideu.com
Country
China
ProdList
8025
Advantage
58
Career Henan Chemica Co
Tel
+86-0371-86658258 +8613203830695
Fax
0371-86658258
Email
laboratory@coreychem.com
Country
China
ProdList
30229
Advantage
58
Shanghai Lanle Bird Industrial Co., Ltd.
Tel
15021845385
Email
765325601@qq.com
Country
China
ProdList
3609
Advantage
58
Hubei xin bonus chemical co. LTD
Tel
86-13657291602
Fax
027-59338440
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
22963
Advantage
58
Wuxi Donghe Pharmaceutical Technology Co., Ltd.
Tel
63313187 15358055255
Fax
QQ：63313187
Email
63313187@qq.com
Country
China
ProdList
1984
Advantage
58
Shanghai Fine Biotech Co.，Ltd
Tel
18717800556
Email
sales@finebiotech.com
Country
China
ProdList
2182
Advantage
58
Zhengzhou Alpha Chemical Co. LTD
Tel
0371-0371-53732842 13383863444
Fax
QQ：3002612166
Email
3002612166@qq.com
Country
China
ProdList
9996
Advantage
58
Shanghai Xuerong Chemical Technology Co., LTD
Tel
18201727566
Fax
QQ:230497258
Email
230497258@qq.com
Country
China
ProdList
513
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44894
Advantage
58
Hubei Co-prosperity Medicine Technonlogy Co., Ltd
Tel
2383948258 19172820304
Email
2383948258@qq.com
Country
China
ProdList
12987
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29757
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 4008210725
Email
malulu@leyan.com
Country
China
ProdList
40000
Advantage
58
Bide Pharmatech Ltd.
Tel
400-1647117 13681763483
Email
product02@bidepharm.com
Country
China
ProdList
59936
Advantage
58
Bide Pharmatech Ltd.
Tel
400-6005915
Email
sales@picasso-e.com
Country
China
ProdList
39665
Advantage
58
Shandong Mingde Biotechnology Co., Ltd
Tel
15553348166
Email
m15553348166@163.com
Country
China
ProdList
9967
Advantage
58
Beijing InnoChem Science & Technology Co., Ltd.
Tel
15652467323
Email
sales@inno-chem.com.cn
Country
China
ProdList
8293
Advantage
58
Guangdong Fangxin Biotechnology Co., Ltd.
Tel
0751-2838688 13376594225
Email
1276075424@qq.com
Country
China
ProdList
9942
Advantage
58
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 17801761073
Email
Gsiyu@solarbio.com
Country
China
ProdList
50751
Advantage
58
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 17801761073
Email
Gsiyu@solarbio.com
Country
China
ProdList
50464
Advantage
58
Shanghai Jieshikai Biotechnology Co. , Ltd.
Tel
021-57520305 13795461237
Email
zhuruyan@jskchem.com
Country
China
ProdList
49234
Advantage
58
PharmaBlock Sciences (Nanjing), Inc.
Tel
4000255188
Email
marketing@pharmablock.com
Country
China
ProdList
9126
Advantage
58
Ningbo Zhenyue Pharmaceutical Technology Co., Ltd
Tel
19817745290
Email
bd@blocksynth.com
Country
China
ProdList
5869
Advantage
58
Baoji Didu Pharmaceutical and Chemical Co., Ltd
Tel
029-81145305 17791533577
Email
1021@dideu.com
Country
China
ProdList
10009
Advantage
58
Shanghai Aladdin Biochemical Technology Co.,Ltd.
Tel
400-6206333 13167063860
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
48457
Advantage
58
Shanghai Zunlijia Life Technology Co., Ltd
Tel
021-34045219 13062664914
Email
huji@zunlijia.com
Country
China
ProdList
10027
Advantage
58
BEIJINGYIWANJINGRUI
Tel
15866847540
Email
dengyt2000@163.com
Country
China
ProdList
4100
Advantage
58
Shanghai Ken chemical Technology Co.,ltd
Tel
02152215958
Email
47697177@qq.com
Country
China
ProdList
10011
Advantage
58
Santa Cruz Biotechnology Inc
Tel
021-60936350
Email
scbt@scbt.com
Country
China
ProdList
6594
Advantage
58
Ningbo Chaoming Biotechnology Co., Ltd
Tel
13301662590
Email
mandy@atkchemical.com
Country
China
ProdList
9343
Advantage
58
ANHUI BYERSEN BIOTECH CO. LTD
Tel
+86-15385096007 +86-17755058861
Email
amy@byersenchemical.com
Country
China
ProdList
10000
Advantage
58
More
Less

View Lastest Price from 3-AMINO-5-HYDROXYMETHYLPYRIDINE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
3-AMINO-5-HYDROXYMETHYLPYRIDINE 443649-18-1
Price
US $1.10/g
Min. Order
1g
Purity
99.0% min
Supply Ability
100 tons min
Release date
2021-05-12

443649-18-1, 3-AMINO-5-HYDROXYMETHYLPYRIDINERelated Search:

5-(Dimethylamino)nicotinic Acid 5-NITRONICOTINIC ACID ETHYL 2-METHYL-5-NITRONICOTINATE 5-Aminonicotinic acid 5-AMINO-NICOTINIC ACID METHYL ESTER 5-ACETAMIDONICOTINIC ACID 5-(METHYLAMINO)NICOTINIC ACID 2-Amino-5-nitronicotinic acid Methyl-6-chloro-5-nitronicotinate 6-Hydroxy-5-nitronicotinic acid 4-AMINO-3-HYDROXYMETHYLPYRIDINE 3-AMINO-4-HYDROXYMETHYLPYRIDINE,3-Amino-4-hydroxymethylpyridine ,96% 6-AMINO-3-HYDROXYMETHYLPYRIDINE,2-AMINO-5-PYRIDINEMETHANOL(2-AMINO-5-HYDROXYMETHYLPYRIDINE) 2-Amino-4-hydroxymethylpyridine 5-MORPHOLIN-4-YL-NICOTINIC ACID 5-(1H-PYRROL-1-YL)NICOTINIC ACID 4,6-Dihydroxy-5-nitropyridine-3-carboxylic acid ethyl ester 5-Amino-3-pyridinecarboxylic acid ethyl ester

  • 3-AMINO-5-HYDROXYMETHYLPYRIDINE
  • 3-Pyridinemethanol,5-amino-(9CI)
  • 3-Amino-5-hydroxymethylpyridine ,97%
  • (5-Aminopyridin-3-yl)methanol
  • 3-PyridineMethanol,5-aMino-
  • 5-Amino-3-(Hydroxymethyl)Pyridine
  • 3-AMINO-5-HYDROXYMETHYLPYRIDINE ISO 9001：2015 REACH
  • (5-amino-3-pyridyl)methanol
  • 443649-18-1
  • PYRIDINE