1H-Benzimidazole-2-methanol
- Product Name
- 1H-Benzimidazole-2-methanol
- CAS No.
- 4856-97-7
- Chemical Name
- 1H-Benzimidazole-2-methanol
- Synonyms
- IFLAB-BB F0266-0027;TIMTEC-BB SBB004085;2-HYDROXYBENXIMIDAZOLE;2-BENZIMIDAZOLEMETHANOL;BENZIMIDAZOLE-2-METHANOL;(2-Benzimidazolyl)methanol;1H-benzimidazol-2-methanol;1H-BENZIMIDAZOLE-2-METHANOL;1H-BENZIMIDAZOL-2-YLMETHANOL;2-HYDROXYMETHYLBENZIMIDAZOLE
- CBNumber
- CB0666493
- Molecular Formula
- C8H8N2O
- Formula Weight
- 148.16
- MOL File
- 4856-97-7.mol
1H-Benzimidazole-2-methanol Property
- Melting point:
- 171-175 °C (lit.)
- Boiling point:
- 268.75°C (rough estimate)
- Density
- 1.1828 (rough estimate)
- refractive index
- 1.6000 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- soluble in Methanol
- pka
- 11.57±0.10(Predicted)
- form
- Crystalline Powder
- color
- Off-white to light brown
- InChI
- InChI=1S/C8H8N2O/c11-5-8-9-6-3-1-2-4-7(6)10-8/h1-4,11H,5H2,(H,9,10)
- InChIKey
- IAJLTMBBAVVMQO-UHFFFAOYSA-N
- SMILES
- C1(CO)NC2=CC=CC=C2N=1
- CAS DataBase Reference
- 4856-97-7(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 20/21/22-36/37/38
- Safety Statements
- 26-36-36/37
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29339900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 158356
- Product name
- 2-Benzimidazolemethanol
- Purity
- 97%
- Packaging
- 5g
- Price
- $103
- Updated
- 2025/07/31
- Product number
- 158356
- Product name
- 2-Benzimidazolemethanol
- Purity
- 97%
- Packaging
- 1g
- Price
- $39.8
- Updated
- 2023/06/20
- Product number
- H1229
- Product name
- 2-(Hydroxymethyl)benzimidazole
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 5g
- Price
- $137
- Updated
- 2025/07/31
- Product number
- B204065
- Product name
- (1H-Benzoimidazol-2-yl)methanol
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- B204065
- Product name
- (1H-Benzoimidazol-2-yl)methanol
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
1H-Benzimidazole-2-methanol Chemical Properties,Usage,Production
Chemical Properties
Off-white to light brown crystalline powder
Uses
2-Benzimidazolemethanol was used in the preparation of 2-(chloromethyl)-1-(methylsulfonyl)benzimidazole via methanesulfonylation. It was also used in the synthesis of 1H-benzimidazol-2-ylmethyl diethyl phosphate.
Synthesis
79-14-1
95-54-5
4856-97-7
The compound was prepared based on known methods with some modifications [19,20]. O-phenylenediamine (27 g, 0.25 mol) was dissolved in 500 mL of 4 M HCl, mixed with a solution of ethanoic acid (34.2 g, 0.45 mol) in 250 mL of 4 M HCl, stirred and heated under reflux conditions for 2 hours. Upon completion of the reaction, the reaction mixture was slowly cooled to room temperature and subsequently alkalized to pH neutral with aqueous sodium hydroxide. The precipitated solid was separated by filtration, dried and purified by recrystallization using hot water (Scheme 1). Product I was obtained: white to light brown powder, melting point 171-174 °C, yield 89.1%.
References
[1] Molecules, 2015, vol. 20, # 8, p. 15206 - 15223
[2] Bulletin of the Chemical Society of Ethiopia, 2014, vol. 28, # 3, p. 451 - 456
[3] Monatshefte fur Chemie, 2016, vol. 147, # 12, p. 2209 - 2220
[4] Patent: CN106905241, 2017, A. Location in patent: Paragraph 0127-0129
[5] Patent: CN107118249, 2017, A. Location in patent: Paragraph 0117; 0118; 0119
1H-Benzimidazole-2-methanol Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1H-Benzimidazole-2-methanol manufacturers
- Product
- 1H-Benzimidazole-2-methanol 4856-97-7
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- 1H-Benzimidazole-2-methanol 4856-97-7
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09
- Product
- 1H-Benzimidazole-2-methanol 4856-97-7
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-27