ChemicalBook > CAS DataBase List > SR27897

SR27897

Product Name
SR27897
CAS No.
136381-85-6
Chemical Name
SR27897
Synonyms
SR27897;SR 27897 hydrate;{2-[4-(2-Chloro-phenyl)-thiazol-2-ylcarbamoyl]-indol-1-yl}-acetic acid;2-[[[4-(2-Chlorophenyl)-2-thiazolyl]amino]carbonyl]-1H-indole-1-aceticacid;2-(2-((4-(2-Chlorophenyl)thiazol-2-yl)carbamoyl)-1H-indol-1-yl)acetic acid;1H-Indole-1-acetic acid,2-[[[4-(2-chlorophenyl)-2-thiazolyl]amino]carbonyl]-;2-[[[4-(2-chlorophenyl)-2-thiazolyl]amino]carbonyl]-1H-indole-1-acetic acid hydrate
CBNumber
CB11074591
Molecular Formula
C20H14ClN3O3S
Formula Weight
411.86
MOL File
136381-85-6.mol
More
Less

SR27897 Property

Density 
1.49±0.1 g/cm3(Predicted)
storage temp. 
Desiccate at +4°C
solubility 
DMSO: ≥10mg/mL at warmed to 60°C
pka
4.00±0.10(Predicted)
form 
powder
color 
white to tan
More
Less

Safety

Hazard Codes 
T
Risk Statements 
25-41
Safety Statements 
26-45
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
28511
Product name
SR 27897
Packaging
5mg
Price
$117
Updated
2024/03/01
Cayman Chemical
Product number
28511
Product name
SR 27897
Packaging
50mg
Price
$866
Updated
2024/03/01
Cayman Chemical
Product number
28511
Product name
SR 27897
Packaging
10mg
Price
$210
Updated
2024/03/01
Cayman Chemical
Product number
28511
Product name
SR 27897
Packaging
25mg
Price
$463
Updated
2024/03/01
Tocris
Product number
2190
Product name
SR27897
Purity
≥99%(HPLC)
Packaging
10
Price
$231
Updated
2021/12/16
More
Less

SR27897 Chemical Properties,Usage,Production

Uses

SR 27897 is a human cholecystokinin type 1 (CCK1) competitive antagonist.

Definition

ChEBI: 2-[2-[[[4-(2-chlorophenyl)-2-thiazolyl]amino]-oxomethyl]-1-indolyl]acetic acid is an indolyl carboxylic acid.

Biological Activity

Potent, non-peptide CCK 1 receptor antagonist that displays > 33-fold selectivity over CCK 2 receptors (EC 50 values are 6 and 200 nM respectively). Causes an increase in plasma leptin levels and increases food intake in rats in vivo .

storage

Store at +4°C

SR27897 Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

SR27897 Suppliers

Tocris Bioscience
Tel
--
Fax
--
Email
customerservice@tocris.co.uk
Country
United Kingdom
ProdList
5726
Advantage
77

136381-85-6, SR27897Related Search:


  • SR27897
  • 2-[[[4-(2-Chlorophenyl)-2-thiazolyl]amino]carbonyl]-1H-indole-1-aceticacid
  • 2-[[[4-(2-chlorophenyl)-2-thiazolyl]amino]carbonyl]-1H-indole-1-acetic acid hydrate
  • SR 27897 hydrate
  • 1H-Indole-1-acetic acid,2-[[[4-(2-chlorophenyl)-2-thiazolyl]amino]carbonyl]-
  • {2-[4-(2-Chloro-phenyl)-thiazol-2-ylcarbamoyl]-indol-1-yl}-acetic acid
  • 2-(2-((4-(2-Chlorophenyl)thiazol-2-yl)carbamoyl)-1H-indol-1-yl)acetic acid
  • 136381-85-6