SR27897
- Product Name
- SR27897
- CAS No.
- 136381-85-6
- Chemical Name
- SR27897
- Synonyms
- SR27897;SR 27897 hydrate;Lintitript, 10 mM in DMSO;SR 27897 (Lintitript), CCK1 receptor antagonist;{2-[4-(2-Chloro-phenyl)-thiazol-2-ylcarbamoyl]-indol-1-yl}-acetic acid;2-[[[4-(2-Chlorophenyl)-2-thiazolyl]amino]carbonyl]-1H-indole-1-aceticacid;2-(2-((4-(2-Chlorophenyl)thiazol-2-yl)carbamoyl)-1H-indol-1-yl)acetic acid;1H-Indole-1-acetic acid,2-[[[4-(2-chlorophenyl)-2-thiazolyl]amino]carbonyl]-;2-[[[4-(2-chlorophenyl)-2-thiazolyl]amino]carbonyl]-1H-indole-1-acetic acid hydrate
- CBNumber
- CB11074591
- Molecular Formula
- C20H14ClN3O3S
- Formula Weight
- 411.86
- MOL File
- 136381-85-6.mol
SR27897 Property
- Density
- 1.49±0.1 g/cm3(Predicted)
- storage temp.
- Desiccate at +4°C
- solubility
- DMSO: ≥10mg/mL at warmed to 60°C
- pka
- 4.00±0.10(Predicted)
- form
- powder
- color
- white to tan
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H318Causes serious eye damage
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 28511
- Product name
- SR 27897
- Packaging
- 5mg
- Price
- $117
- Updated
- 2024/03/01
- Product number
- 28511
- Product name
- SR 27897
- Packaging
- 50mg
- Price
- $866
- Updated
- 2024/03/01
- Product number
- 28511
- Product name
- SR 27897
- Packaging
- 10mg
- Price
- $210
- Updated
- 2024/03/01
- Product number
- 28511
- Product name
- SR 27897
- Packaging
- 25mg
- Price
- $463
- Updated
- 2024/03/01
- Product number
- 2190
- Product name
- SR27897
- Purity
- ≥99%(HPLC)
- Packaging
- 10
- Price
- $231
- Updated
- 2021/12/16
SR27897 Chemical Properties,Usage,Production
Uses
SR 27897 is a human cholecystokinin type 1 (CCK1) competitive antagonist.
Definition
ChEBI: 2-[2-[[[4-(2-chlorophenyl)-2-thiazolyl]amino]-oxomethyl]-1-indolyl]acetic acid is an indolyl carboxylic acid.
Biological Activity
Potent, non-peptide CCK 1 receptor antagonist that displays > 33-fold selectivity over CCK 2 receptors (EC 50 values are 6 and 200 nM respectively). Causes an increase in plasma leptin levels and increases food intake in rats in vivo .
storage
Store at +4°C
SR27897 Preparation Products And Raw materials
Raw materials
Preparation Products
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