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Antazoline hydrochloride

Product Name
Antazoline hydrochloride
CAS No.
2508-72-7
Chemical Name
Antazoline hydrochloride
Synonyms
histazine;fenazolina;Antazolin Hcl;ANTAZOLINE HCL;Phenazocine HCl;Antazoline. HCL forM;LABOTEST-BB LT00134672;antistinehydrochloride;Antazolin hydrochloride;ANTAZOLINE HYDROCHLORIDE
CBNumber
CB1115857
Molecular Formula
C17H20ClN3
Formula Weight
301.81
MOL File
2508-72-7.mol
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Antazoline hydrochloride Property

Melting point:
238 °C
storage temp. 
Inert atmosphere,Room Temperature
solubility 
DMSO (Slightly, Heated), Methanol (Slightly)
form 
Solid
color 
White to Off-White
Merck 
14,680
CAS DataBase Reference
2508-72-7(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
20/21/22-36/37/38
Safety Statements 
26-36
WGK Germany 
3
RTECS 
NJ2150000
HS Code 
2933.29.4300
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A9899
Product name
Antazoline hydrochloride
Packaging
25g
Price
$106.8
Updated
2024/03/01
Sigma-Aldrich
Product number
A1210000
Product name
Antazoline hydrochloride
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
a1210000
Price
$223
Updated
2024/03/01
TCI Chemical
Product number
A2132
Product name
Antazoline Hydrochloride
Purity
>99.0%(T)
Packaging
25g
Price
$89
Updated
2024/03/01
Alfa Aesar
Product number
J62511
Product name
Antazoline hydrochloride
Purity
98%
Packaging
5g
Price
$0
Updated
2021/12/16
Alfa Aesar
Product number
J62511
Product name
Antazoline hydrochloride, 98%
Packaging
25g
Price
$0
Updated
2021/12/16
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Antazoline hydrochloride Chemical Properties,Usage,Production

Chemical Properties

White or almost white crystalline powder

Originator

Antistine HCl,Ciba,US,1948

Uses

Antazoline Hydrochloride acts as a histamine H1 receptor blocker, functioning as an antihistamine pharmaceutical.

Uses

Antihistaminic;H1 antagonist

Uses

Imidazoline binding site ligand and an antihistamine

Manufacturing Process

15.4 parts of 2-chloromethylimidazoline hydrochloride, 45.8 parts of Nbenzylaniline and 150 parts of alcohol are heated in an oil bath at 100° to 110°C. After distilling off the alcohol, the reaction mass is maintained at this temperature for a further 3 hours and then triturated with water and 10 parts of sodium bicarbonate. The unconsumed benzylaniline is extracted with ether and the aqueous solution neutralized with dilute hydrochloric acid. By evaporating this solution and extracting the residue with alcohol there is obtained 2-(N-phenyl-N-benzylaminomethyl)imidazoline hydrochloride in the form of colorless crystals of melting point 227° to 229°C.

Therapeutic Function

Antihistaminic

Biological Activity

Imidazoline binding site ligand; a potent inducer of insulin secretion in rat pancreas. Also an antihistamine.

Antazoline hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Antazoline hydrochloride Suppliers

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View Lastest Price from Antazoline hydrochloride manufacturers

Hebei Ganmiao New material Technology Co., LTD
Product
Antazoline hydrochloride 2508-72-7
Price
US $13.00-7.00/kg
Min. Order
1kg
Purity
99.9%
Supply Ability
200ton
Release date
2024-06-19
Hebei Mojin Biotechnology Co.,Ltd
Product
Antazoline Hydrochloride 2508-72-7
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
50000KG/month
Release date
2024-07-22
Zhuozhou Wenxi import and Export Co., Ltd
Product
Antazoline hydrochloride 2508-72-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11

2508-72-7, Antazoline hydrochlorideRelated Search:


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  • Phenazoline hydrochloride
  • LABOTEST-BB LT00134672
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  • 2-(N-PHENYL-N-BENZYL-AMINOMETHYL)-IMIDAZOLINE HCL
  • 2-(N-BENZYLANILINOMETHYL)-2-IMIDAZOLINE HYDROCHLORIDE
  • 2-(N-BENZYLANILINOMETHYL) IMIDAZOLINE HYDROCHLORIDE
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  • ANTAZOLINE HYDROCHLORIDE
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  • N-BENZYL-N-(2-IMIDAZOLIN-2-YLMETHYL)ANILINE HYDROCHLORIDE
  • 2-((n-benzylanilino)methyl)-2-imidazolinhydrochloride
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  • Antazoline. HCL forM
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  • 2-(n-phenyl-n-benzylaminomethyl)imidazolinehydrochloride
  • 2-phenylbenzylaminomethylimidazolinehydrochloride
  • antistinehydrochloride
  • fenazolina
  • histazine
  • Antazolin Hcl
  • 2-(N-Benzyl-N-phenylaminonomethyl)-2-imidazoline
  • N-BENZYL-N-(2-IMIDAZOLIN-2-YLMETHY)ANILINE
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  • a ni ma l e pi th e li a a nd Outg rowth s f or a lle rg e n Prod uc ts
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  • 2508-72-7
  • C17H20ClN3
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  • Imidazoline agonist; more potent than efaroxan in inducing insulin release from beta cells; H1 histamine receptor antagonist.
  • Histamine receptor
  • 2508-72-7