ChemicalBook > CAS DataBase List > 3'-Bromo-4'-fluoroacetophenone

3'-Bromo-4'-fluoroacetophenone

Product Name
3'-Bromo-4'-fluoroacetophenone
CAS No.
1007-15-4
Chemical Name
3'-Bromo-4'-fluoroacetophenone
Synonyms
1-(3-bromo-4-fluorophenyl)ethan-1-one;1-(3-BROMO-4-FLUOROPHENYL)ETHANONE;3-Bromo-4-fluoroacetphenone;3-BROMO-4-FLUOROACETOPHENONE;3'-Bromo-4'-fluoroacetophone;3'-Bromo-4'-fluoroacetophenone;4-Acetyl-2-bromo-1-fluorobenzene;3'-Bromo-4'-fluoroacetophenone97%;3'-Bromo-4'-fluoroacetophenone >3- BROMO-4-FLUOROACETOPHENONE 98+%
CBNumber
CB1160958
Molecular Formula
C8H6BrFO
Formula Weight
217.04
MOL File
1007-15-4.mol
More
Less

3'-Bromo-4'-fluoroacetophenone Property

Melting point:
52-57 °C(lit.)
Boiling point:
150°C 12mm
Density 
1.5728 (rough estimate)
refractive index 
1.5450 (estimate)
Flash point:
>230 °F
storage temp. 
Sealed in dry,Room Temperature
form 
powder to crystal
color 
White to Orange to Green
BRN 
3088698
CAS DataBase Reference
1007-15-4(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29147000
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
339679
Product name
3′-Bromo-4′-fluoroacetophenone
Purity
96%
Packaging
25g
Price
$349
Updated
2023/06/20
TCI Chemical
Product number
B2014
Product name
3'-Bromo-4'-fluoroacetophenone
Purity
>96.0%(GC)
Packaging
5g
Price
$82
Updated
2025/07/31
TCI Chemical
Product number
B2014
Product name
3'-Bromo-4'-fluoroacetophenone
Purity
>96.0%(GC)
Packaging
25g
Price
$326
Updated
2025/07/31
TRC
Product number
B691883
Product name
3''-Bromo-4''-fluoroacetophone
Packaging
1g
Price
$55
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
JK178609
Product name
3'-Bromo-4'-fluoroacetophenone
Purity
97%
Packaging
5g
Price
$71
Updated
2021/12/16
More
Less

3'-Bromo-4'-fluoroacetophenone Chemical Properties,Usage,Production

Chemical Properties

White to yellowish low melting soli

General Description

3′-Bromo-4′-fluoroacetophenone is also referred as 3-bromo-4-fluoro-acetophenone. Palladium-catalyzed amination of 3-bromo-4-fluoro-acetophenone has been reported.

Synthesis

403-42-9

176548-69-9

1007-15-4

Example A5: Synthesis of 1-(3,5-dibromo-4-fluorophenyl)ethan-1-one and 1-(3-bromo-4-fluorophenyl)ethan-1-one 69 g (0.5 mol) of 4-fluoroacetophenone was slowly added dropwise to 200.0 g (1.5 mol) of finely powdered aluminum and heated to 70 °C with stirring. The reaction temperature was maintained at 75-80 °C for 20 min, followed by the slow addition of 184 g (1.15 mol) of bromine at the same temperature over a period of 2.5 hours. After completion of the reaction, the mixture was heated to 90 °C and maintained for 3 hours. After cooling, decolorization was carried out and then the mixture was partitioned between water and tert-butyl methyl ether. The organic phase was separated to give 130 g of brownish black oil. The oily substance was separated by column chromatography on toluene, using toluene as eluent, to give a two-part product: a) 41.2 g (28% of theoretical yield) of colorless crystals with a melting point of 59-62 °C and an Rf = 0.53 (toluene). Identified by spectral analysis as 1-(3,5-dibromo-4-fluorophenyl)-1-ethanone. IR (KBr): 1685 (C=O) cm?1; MS: M? = 294/296/298 (Br?). b) 41.2 g (28% of the theoretical yield) colorless crystals, melting point 59-62 °C, Rf = 0.53 (toluene). b) 46.0 g (42% of theoretical yield) colorless crystals, melting point 52-55 °C, Rf = 0.41 (toluene). Identified by spectral analysis as 1-(3-bromo-4-fluorophenyl)-1-ethanone. IR (KBr): 1682 (C=O) cm?1; MS: M? = 216/218 (Br). c) 46.0 g (42% of theoretical yield) colorless crystals, melting point 52-55 °C, Rf = 0.41 (toluene).

References

[1] Patent: US7230001, 2007, B1. Location in patent: Page/Page column 67-68

3'-Bromo-4'-fluoroacetophenone Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

3'-Bromo-4'-fluoroacetophenone Suppliers

Americas 1 Belgium 3 China 167 Europe 1 France 2 Germany 4 India 10 Italy 1 Japan 5 Slovakia 1 Switzerland 3 Ukraine 2 United Kingdom 16 United States 53 Global 269
Alfa Chemistry
Tel
+1-5166625404;
Fax
1-516-927-0118
Email
Info@alfa-chemistry.com
Country
United States
ProdList
20405
Advantage
58
Accela ChemBio Inc.
Tel
+1-858-6993322
Fax
(+1)-858-876-1948
Email
info@accelachem.com
Country
United States
ProdList
21193
Advantage
58
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Aceschem Inc.
Tel
+1-817863-6948 +1-（817）863-6948
Email
sales@aceschem.com
Country
United States
ProdList
19632
Advantage
58
Synthonix Inc
Tel
--
Fax
--
Email
info@synthonix.com
Country
United States
ProdList
6872
Advantage
58
BromOrganics Corporation
Tel
--
Fax
--
Email
sales@bromorganics.com
Country
United States
ProdList
1065
Advantage
58
MilliporeSigma (Sigma-Aldrich Corp.)
Tel
--
Fax
--
Email
@sial.com
Country
United States
ProdList
5414
Advantage
58
SynQuest Laboratories, Inc.,
Tel
--
Fax
--
Country
United States
ProdList
2301
Advantage
58
Crescent Chemical Company
Tel
--
Fax
--
Email
fran@creschem.com
Country
United States
ProdList
1441
Advantage
58
Pennbio Chemicals (U.S.A.)
Tel
--
Fax
--
Country
United States
ProdList
240
Advantage
58
SynQuest Laboratories, Inc. (Part of Central Glass Co., Ltd.)
Tel
--
Fax
--
Email
nfo@synquestlabs.com
Country
United States
ProdList
1897
Advantage
58
Alichem Inc.
Tel
--
Fax
--
Email
sales@alichem.com
Country
United States
ProdList
6167
Advantage
58
TCI America, Inc. (Tokyo Chemical Industry Co., Ltd.)
Tel
--
Fax
--
Email
.Crew@tcichemicals.com
Country
United States
ProdList
3164
Advantage
58
Redox Scientific
Tel
--
Fax
--
Email
info@redoxsci.com
Country
United States
ProdList
2380
Advantage
58
Fluorochem Ltd.
Tel
--
Fax
--
Email
enquiries@fluorochem.co.uk
Country
United States
ProdList
4583
Advantage
58
Brightek LLC
Tel
--
Fax
--
Country
United States
ProdList
782
Advantage
58
VWR International, LLC.
Tel
--
Fax
--
Email
@sargentwelch.com
Country
United States
ProdList
6262
Advantage
58
AOBChem
Tel
--
Fax
--
Email
sales@aobchem.com
Country
United States
ProdList
885
Advantage
58
Esprix Technologies
Tel
--
Fax
--
Email
info@esprixtech.com
Country
United States
ProdList
619
Advantage
58
SynChem，Inc
Tel
--
Fax
--
Email
sales@synchem.com
Country
United States
ProdList
4697
Advantage
58
SynQuest Laboratories, Inc.
Tel
--
Fax
--
Email
info@synquestlabs.com
Country
United States
ProdList
6871
Advantage
62
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
TCI America
Tel
--
Fax
--
Email
sales@tciamerica.com
Country
United States
ProdList
6909
Advantage
75
Frontier Scientific, Inc.
Tel
--
Fax
--
Email
sales@frontiersci.com
Country
United States
ProdList
6222
Advantage
86
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
Frontier Scientific Services, Inc.
Tel
--
Fax
--
Email
customerservice@frontierssi.com
Country
United States
ProdList
1575
Advantage
0
Accela ChemBio Inc.
Tel
--
Fax
--
Email
info@accelachem.com
Country
United States
ProdList
1054
Advantage
50
AOBChem USA
Tel
--
Fax
--
Email
sales@aobchem.com
Country
United States
ProdList
3487
Advantage
50
Chirofine Chemicals Company
Tel
--
Fax
--
Country
United States
ProdList
41
Advantage
38
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6962
Advantage
56
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
AlliChem, LLC
Tel
--
Fax
--
Email
sales@allichemllc.com
Country
United States
ProdList
6516
Advantage
60
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
Ryan Scientific, Inc.
Tel
--
Fax
--
Email
ryan.reichlyn@ryansci.com
Country
United States
ProdList
6439
Advantage
60
INDOFINE Chemical Company, Inc.
Tel
--
Fax
--
Email
chemical@indofinechemical.com
Country
United States
ProdList
6176
Advantage
69
AK Scientific, Inc.
Tel
--
Fax
--
Email
sales@aksci.com
Country
United States
ProdList
6347
Advantage
65
Oakwood Products, Inc.
Tel
--
Fax
--
Email
sales@oakwoodchemical.com
Country
United States
ProdList
6193
Advantage
74
Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
United States
ProdList
6814
Advantage
81
HONEST JOY HOLDINGS LIMITED
Tel
--
Fax
--
Email
sales@honestjoy.cn
Country
United States
ProdList
6675
Advantage
54
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
APAC Pharmaceutical, LLC
Tel
--
Fax
--
Email
sales@apacpharma.com
Country
United States
ProdList
6322
Advantage
38
R. K. Associate
Tel
--
Fax
--
Country
United States
ProdList
194
Advantage
30
Chontech, Inc.
Tel
--
Fax
--
Email
chontech@yahoo.com
Country
United States
ProdList
1101
Advantage
30
ASDI Incorporated
Tel
--
Fax
--
Email
customerservice@asdi.net
Country
United States
ProdList
6922
Advantage
67
Beta Pharma, Inc.
Tel
--
Fax
--
Email
sales@betapharma.com
Country
United States
ProdList
6226
Advantage
60
Esprit Chemical Company
Tel
--
Fax
--
Email
admin@esprixtech.com
Country
United States
ProdList
1616
Advantage
55
Marshallton Research Laboratories Inc.
Tel
--
Fax
--
Email
marshallton@windstream.net
Country
United States
ProdList
513
Advantage
59
ChemPacific Corporation
Tel
--
Fax
--
Email
sales@chempacific.com
Country
United States
ProdList
6891
Advantage
51
Honeywell Specialty Chemicals Seelze GmbH
Tel
--
Fax
--
Email
ofc@honeywell.com
Country
United States
ProdList
639
Advantage
87
More
Less

View Lastest Price from 3'-Bromo-4'-fluoroacetophenone manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
3'-Bromo-4'-fluoroacetophenone 1007-15-4
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2024-12-09
Shaanxi Dideu Medichem Co. Ltd
Product
3'-Bromo-4'-fluoroacetophenone 1007-15-4
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
1000KG
Release date
2024-07-16
Zhuozhou Wenxi import and Export Co., Ltd
Product
3"-Bromo-4"-fluoroacetophenone 1007-15-4
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11

1007-15-4, 3'-Bromo-4'-fluoroacetophenoneRelated Search:

4'-Bromoacetophenone Bromocriptine mesylate PIPERACETAZINE (250 MG) Florfenicol 2-Bromoacetophenone 2,4-Dinitrofluorobenzene Bromine 3'-Bromo-2'-Fluoroacetophenone ALPHA-BROMO-3-FLUOROACETOPHENONE,2-BROMO-3'-FLUOROACETOPHENONE 3'-BROMO-4'-FLUOROPROPIOPHENONE 2'-Bromo-4'-fluoroacetophenone97%,2'-Bromo-4'-fluoroacetophenone 97% 2-Bromo-4'-fluoroacetophenone 2'-BROMO-5'-FLUOROACETOPHENONE 2-BROMO-2'-FLUOROACETOPHENONE 4-Fluoroacetophenone 1-(4-Bromo-2-fluorophenyl)ethanone 2,3'-DIBROMO-4'-FLUOROACETOPHENONE, 97% 3-(3'-BROMO-4'-FLUOROPHENYL)-3-OXOPROPANENITRILE

  • 3-BROMO-4-FLUOROACETOPHENONE
  • 1-(3-bromo-4-fluorophenyl)ethan-1-one
  • 1-(3-BROMO-4-FLUOROPHENYL)ETHANONE
  • 3- BROMO-4-FLUOROACETOPHENONE 98+%
  • 3'-Bromo-4'-fluoroacetophenone97%
  • Ethanone, 1-(3-bromo-4-fluorophenyl)-
  • 3-Bromo-4-fluorophenyl(methyl) ketone
  • 3'-Bromo-4'-fluoroacetophone
  • 4-Acetyl-2-bromo-1-fluorobenzene
  • 3'-Bromo-4'-fluoroacetophenone &gt
  • 3'-Bromo-4'-fluoroacetophenone
  • 3′-Bromo-4′-fluoroacetophenone, CAS 1007-15-4
  • 3-Bromo-4-fluoroacetphenone
  • 1007-15-4
  • BrC6H3FCOCH3
  • ARYL HALIDE
  • Building Blocks
  • C7 to C8
  • Carbonyl Compounds
  • Organic Building Blocks
  • Ketones
  • Aryl Fluorinated Building Blocks
  • Building Blocks
  • C7 to C8
  • C7-C8
  • Carbonyl Compounds
  • Chemical Synthesis
  • Fluorinated Building Blocks
  • Organic Building Blocks
  • Organic Fluorinated Building Blocks
  • Other Fluorinated Organic Building Blocks
  • Fluorine series
  • C7 to C8
  • Carbonyl Compounds
  • Ketones
  • Adehydes, Acetals & Ketones
  • Bromine Compounds
  • Fluorine Compounds
  • Aromatic Halides (substituted)