ChemicalBook > CAS DataBase List > 4-Chloroanisole

4-Chloroanisole

Product Name
4-Chloroanisole
CAS No.
623-12-1
Chemical Name
4-Chloroanisole
Synonyms
1-CHLORO-4-METHOXYBENZENE;P-CHLOROANISOLE;para-Chloroanisole;4-Methoxyphenyl chloride;p-chloroanisol;4-Chloroanisol;Chloro anisole;4-CHLOROANISOLE;3 4-Chloroanisole;Anisole, p-chloro-
CBNumber
CB1312283
Molecular Formula
C7H7ClO
Formula Weight
142.58
MOL File
623-12-1.mol
More
Less

4-Chloroanisole Property

Melting point:
-18 °C (lit.)
Boiling point:
198-202 °C (lit.)
Density 
1.164 g/mL at 25 °C (lit.)
vapor pressure 
1.08hPa at 25℃
refractive index 
n20/D 1.535(lit.)
Flash point:
173 °F
storage temp. 
Sealed in dry,Room Temperature
form 
Liquid
color 
Clear colorless to yellow
Water Solubility 
immiscible
BRN 
1858901
Stability:
Stable. Combustible. Incompatible with strong oxidizing agents.
LogP
2.78 at 25℃
CAS DataBase Reference
623-12-1(CAS DataBase Reference)
NIST Chemistry Reference
Benzene, 1-chloro-4-methoxy-(623-12-1)
EPA Substance Registry System
Benzene, 1-chloro-4-methoxy- (623-12-1)
More
Less

Safety

Hazard Codes 
Xn
Safety Statements 
23-24/25
RIDADR 
UN 2810
WGK Germany 
3
TSCA 
Yes
HS Code 
29093090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H227Combustible liquid

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
159069
Product name
4-Chloroanisole
Purity
99%
Packaging
25g
Price
$102
Updated
2024/03/01
Sigma-Aldrich
Product number
159069
Product name
4-Chloroanisole
Purity
99%
Packaging
100g
Price
$286
Updated
2023/06/20
TCI Chemical
Product number
C0122
Product name
4-Chloroanisole
Purity
>98.0%(GC)
Packaging
25g
Price
$44
Updated
2024/03/01
TCI Chemical
Product number
C0122
Product name
4-Chloroanisole
Purity
>98.0%(GC)
Packaging
500g
Price
$252
Updated
2024/03/01
Alfa Aesar
Product number
A11377
Product name
4-Chloroanisole, 99%
Packaging
50g
Price
$57.65
Updated
2024/03/01
More
Less

4-Chloroanisole Chemical Properties,Usage,Production

Chemical Properties

colourless liquid

Uses

4-Chloroanisole was found to react with Cu (II)-smectite forming a blue clay-organic complex. 4-Chloroanisole was chosen as the main test substrate for the optimisation studies as it is electronically deactivated and thus resistant to oxidative addition and consequently very reluctant to enter a catalytic manifold.

Synthesis Reference(s)

Chemistry Letters, 16, p. 1901, 1987
The Journal of Organic Chemistry, 35, p. 528, 1970 DOI: 10.1021/jo00827a060

General Description

4-Chloroanisole is an electron-rich chloroarene. It undergoes Ullmann-type homocoupling catalyzed by in situ generated Pd colloids. Reaction of 4-chloroanisole with Cu(II)-smectite in n-hexane, carbon tetrachloride or dichloromethane has been studied. The nucleophilic photosubstitution reactions, photocyanation and photohydrolysis of 4-chloroanisole has been studied by time resolved spectroscopy.

Purification Methods

Wash the anisole with 10% (by volume) aqueous H2SO4 (three times), 10% aqueous KOH (three times), and then with water until neutral. Dry it (MgSO4), and fractionally distil it from CaH2 through a glass helices-packed column under reduced pressure. [Beilstein 16 IV 822.]

4-Chloroanisole Preparation Products And Raw materials

Raw materials

Disulfur dichloride o-Cresol

Preparation Products

More
Less

4-Chloroanisole Suppliers

Americas 1 Belgium 2 Canada 1 China 237 Europe 3 Germany 8 India 24 Japan 4 Slovakia 1 South Korea 1 Switzerland 3 United Kingdom 16 United States 31 Global 332
Shaanxi Coal Chemical Industry Technology Research Institute Co., Ltd.
Tel
029-81772051 15388612296
Email
549981688@qq.com
Country
China
ProdList
29
Advantage
58
Shanghai Boyle Chemical Co., Ltd.
Tel
021-50182298 021-50180596
Fax
+86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2210
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94838
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40240
Advantage
62
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1998
Advantage
65
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057 18501085097
Fax
010-89508210
Email
sales3.gd@hwrkchemical.com
Country
China
ProdList
7639
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18217
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12458
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9984
Advantage
60
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11660
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
Country
China
ProdList
42982
Advantage
64
Shandong Xiya Chemical Co., Ltd
Tel
13355009207 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18739
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12990
Advantage
57
BEST-REAGENT
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11726
Advantage
57
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7815
Advantage
57
RYSS TECH LTD
Tel
400-188-0725 +86 21 34310725 13611771617
Fax
+86 21 34311076
Country
China
ProdList
2002
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14443
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9823
Advantage
79
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11714
Advantage
57
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9725
Advantage
55
T&W GROUP
Tel
021-61551611 13296011611
Fax
＋86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9900
Advantage
58
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9872
Advantage
52
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17779
Advantage
75
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9452
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19918
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22519
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
18521735133 18521732826;
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25015
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9552
Advantage
55
BeiJing Greenchem Technology Co.,Ltd.
Tel
13842764302; 13842764302
Fax
010-62925455
Email
chemrocking@bjgreenchem.com
Country
China
ProdList
461
Advantage
58
Beijing Universal Century Technology Co., Ltd.
Tel
400-8706899
Fax
400-8706899
Email
hysj_bj.com
Country
China
ProdList
3585
Advantage
55
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9986
Advantage
55
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41438
Advantage
60
Mei Lan Industrial (Shanghai) Co., Ltd.
Tel
021-58958189
Fax
021-58957967
Email
wouchina@126.com
Country
China
ProdList
2671
Advantage
55
Shanghai GaoLang Chemical Technology Co., Ltd.
Tel
021-57340939 18017297327
Fax
021-37210791
Email
sales@gaolangchemical.com
Country
China
ProdList
888
Advantage
55
Shanghai ideal Industrial Co., Ltd.
Tel
021-58957966 18930537195
Fax
021-60899437
Email
wouchina@126.com
Country
China
ProdList
3033
Advantage
58
GuangTuo Chemical (Shanghai) Co., Ltd.
Tel
021-60899189-8001 18918189673
Fax
021-60899304
Email
gtchem@126.com
Country
China
ProdList
2661
Advantage
58
Beijing FYF Chemicals Co., Ltd
Tel
010-61647239; 15318973357
Fax
010-57903446
Email
1460285141@qq.com
Country
China
ProdList
2945
Advantage
58
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
15878
Advantage
55
Shanghai Kewel Chemical Co., Ltd.
Tel
021-64609169 18901607656
Fax
021-64609160
Email
greensnown@163.com
Country
China
ProdList
9911
Advantage
50
SHANGHAI BANGCHENG CHEMICAL Co.,Ltd.
Tel
021-69106960 13701823733
Fax
021-69106780
Email
13701823733@163.com
Country
China
ProdList
4775
Advantage
60
Shanghai Jovan Biochemical Technology Co. Ltd.
Tel
+86-021-61654350
Fax
+86-021-61654350
Email
1245958370@qq.com
Country
China
ProdList
2984
Advantage
50
Beijing Xinsavi Chemical Technology Co., Ltd.
Tel
010-56218822 13717722232
Fax
010-56218800
Email
xinsavichem@163.com
Country
China
ProdList
3201
Advantage
56
Beijing Holiyang Chemical Co. Ltd.
Tel
13718199399
Fax
QQ : 206661479
Email
holiyangchem@163.com
Country
China
ProdList
3387
Advantage
56
Shanghai YouPeng Chemical Co. Ltd.
Tel
021-69005955 13701776567
Fax
021-69005775
Email
youpengchem@163.com
Country
China
ProdList
4303
Advantage
56
Sichuan Hainuowei Technology Co. Ltd.
Tel
13708085536
Fax
QQ : 121102042
Email
hanovichem@163.com
Country
China
ProdList
3389
Advantage
56
Shanghai TongYuan Chemical Co., Ltd.
Tel
021-021-69182866 13701855675
Fax
021-69182022
Email
tongyuanchem@126.com
Country
China
ProdList
4331
Advantage
58
Shanghai Kaisai Chemical Co., Ltd
Tel
021-33516722 13701817765
Fax
021-33516776
Email
kaisaichem@163.com
Country
China
ProdList
4751
Advantage
58
More
Less

View Lastest Price from 4-Chloroanisole manufacturers

Hebei Duling International Trade Co. LTD
Product
4-Chloroanisole 623-12-1
Price
US $65.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000 tons
Release date
2023-04-24
Hebei Mojin Biotechnology Co., Ltd
Product
4-Chloroanisole 623-12-1
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-09-07
Hebei Guanlang Biotechnology Co,.LTD
Product
4-Chloroanisole 623-12-1
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 ton
Release date
2021-06-28

623-12-1, 4-ChloroanisoleRelated Search:

Artemether 1,2,4-Trichlorobenzene 1-Methoxy-2-propyl acetate Anisole Dimethyl ether Chlorphenamine maleate Dimefluthrin 4-Chlorostyrene 4'-CHLOROACETANILIDE 4-Methylsulfuryl chlorobenzene 4-Chlorobenzaldehyde 4-Chlorobenzamide 4-Methoxyphenol 4-Methylanisole p-Anisidine 4-Chlorobenzyl cyanide 4-Chlorobenzoic acid 2-Chloroanisole

  • 1-chloro-4-methoxy-benzen
  • 4-Chloroanisol
  • 4-Chlorophenol methyl ether
  • Anisole, p-chloro-
  • Benzene,1-chloro-4-methoxy-
  • para-Chloroanisole
  • p-chloroanisol
  • p-Chloromethoxybenzene
  • p-Chlorophenyl methyl ether
  • 4-CHLOROANISOLE
  • 1-CHLORO-4-METHOXYBENZENE
  • P-CHLOROANISOLE
  • Chloro anisole
  • 4-chloroMethyl ether
  • 3 4-Chloroanisole
  • 4-Chlorophenyl methyl ether
  • 4-CHLOROANISOLE PESTANAL
  • 4-Chloroanisole,98%
  • 2-methyl-4-chloro phenol，4-chloro anisole
  • 4-Methoxyphenyl chloride
  • Methyl(4-chlorophenyl) ether
  • 4-Chloroanisole,99%
  • 4-Chloroanisole &gt
  • 2,4-Dichlorobenzyl Alcohol Impurity 62
  • 623-12-1
  • 623-12-7
  • 632-12-1
  • Ethers
  • Building Blocks
  • Oxygen Compounds
  • Organic Building Blocks
  • Aromatic Ethers
  • Anisoles, Alkyloxy Compounds & Phenylacetates
  • Chlorine Compounds
  • Ethers
  • Organic Building Blocks
  • Oxygen Compounds
  • 623-12-1