3-Amino-6-cyanopyridine
- Product Name
- 3-Amino-6-cyanopyridine
- CAS No.
- 55338-73-3
- Chemical Name
- 3-Amino-6-cyanopyridine
- Synonyms
- 5-Aminopicolinonitrile;2-Cyano-5-Aminopyridine;5-AMINO-2-CYANOPYRIDINE;3-AMINO-6-CYANOPYRIDINE;5-Amino-2-pyridine nitrile;A**5-AMINO-2-CYANOPYRIDINE;5-Methyl pyridin-3-methanol;5-Aminopyridin-2-carbonitrile;3-AMino-6-pyridinecarbonitrile;2-carbonitrile-5-aminopyridine
- CBNumber
- CB1451232
- Molecular Formula
- C6H5N3
- Formula Weight
- 119.12
- MOL File
- 55338-73-3.mol
3-Amino-6-cyanopyridine Property
- Melting point:
- 148-152 °C(lit.)
- Boiling point:
- 368.2±27.0 °C(Predicted)
- Density
- 1.23±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- 0.61±0.10(Predicted)
- Appearance
- Light yellow to brown Solid
- InChI
- InChI=1S/C6H5N3/c7-3-6-2-1-5(8)4-9-6/h1-2,4H,8H2
- InChIKey
- IFOXWHQFTSCNQB-UHFFFAOYSA-N
- SMILES
- C1(C#N)=NC=C(N)C=C1
- CAS DataBase Reference
- 55338-73-3(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 20/21/22-36/37/38
- Safety Statements
- 26-36
- RIDADR
- 3439
- WGK Germany
- 3
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 538906
- Product name
- 5-Amino-2-pyridinecarbonitrile
- Purity
- 96%
- Packaging
- 25g
- Price
- $172.5
- Updated
- 2025/07/31
- Product number
- 538906
- Product name
- 5-Amino-2-pyridinecarbonitrile
- Purity
- 96%
- Packaging
- 100g
- Price
- $284.5
- Updated
- 2025/07/31
- Product number
- A3358
- Product name
- 5-Aminopicolinonitrile
- Purity
- min. 98.0 %
- Packaging
- 1G
- Price
- $87
- Updated
- 2025/07/31
- Product number
- A3358
- Product name
- 5-Aminopicolinonitrile
- Purity
- min. 98.0 %
- Packaging
- 5G
- Price
- $262
- Updated
- 2025/07/31
- Product number
- A615410
- Product name
- 5-Aminopicolinonitrile
- Packaging
- 1g
- Price
- $55
- Updated
- 2021/12/16
3-Amino-6-cyanopyridine Chemical Properties,Usage,Production
Chemical Properties
Brown powder
Uses
5-Amino-2-pyridinecarbonitrile (5-Amino-2-cyanopyridine) may be used to synthesize 5-amino-2-pyridine.
Synthesis
100367-55-3
55338-73-3
The general procedure for the synthesis of 3-amino-6-cyanopyridine from 2-cyano-5-nitropyridine was as follows: to a solution of 5-nitropyridine-2-carbonitrile (7.0 g, 46.9 mmol) in methanol (150 mL) was added 10% palladium carbon catalyst (2.0 g) and ammonium carbamate (7.0 g, 115 mmol). The reaction mixture was heated under reflux conditions for 16 hours. Upon completion of the reaction, the mixture was filtered to remove the catalyst and the filtrate was concentrated under reduced pressure. The concentrated residue was dissolved in water (150 mL) and subsequently extracted with ethyl acetate (150 mL × 3). The organic layers were combined, dried over anhydrous sodium sulfate, and then concentrated under reduced pressure to give 5.1 g of 5-aminopyridine-2-carbonitrile in 91.3% yield.
References
[1] Patent: WO2015/22301, 2015, A1. Location in patent: Page/Page column 28
[2] Journal of Medicinal Chemistry, 1994, vol. 37, # 1, p. 18 - 25
[3] Organic Process Research and Development, 2004, vol. 8, # 1, p. 62 - 71
[4] Patent: CN106810494, 2017, A. Location in patent: Paragraph 0030; 0031
[5] Patent: WO2017/184547, 2017, A1. Location in patent: Paragraph 00384
3-Amino-6-cyanopyridine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-Amino-6-cyanopyridine manufacturers
- Product
- 3-Amino-6-cyanopyridine 55338-73-3
- Price
- US $0.00-0.00/kg/Drum
- Min. Order
- 25kg/Drum
- Purity
- 98.0%
- Supply Ability
- 1000KG
- Release date
- 2025-04-29
- Product
- 3-Amino-6-cyanopyridine 55338-73-3
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2021-05-12
- Product
- 3-Amino-6-cyanopyridine 55338-73-3
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-14