ChemicalBook > CAS DataBase List > PROTAC K-Ras Degrader-1
PROTAC K-Ras Degrader-1
- Product Name
- PROTAC K-Ras Degrader-1
- CAS No.
- 2378258-52-5
- Chemical Name
- PROTAC K-Ras Degrader-1
- Synonyms
- K-Ras Degrader-1;PROTAC K-Ras Degrader-1;2-Piperazineacetonitrile, 4-[2-[[(2S,4R)-4-[2-[2-[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]ethoxy]ethoxy]-1-methyl-2-pyrrolidinyl]methoxy]-5,6,7,8-tetrahydro-7-(1-naphthalenyl)pyrido[3,4-d]pyrimidin-4-yl]-1-(1-oxo-2-propen-1-yl)-, (2S)-
- CBNumber
- CB15540584
- Molecular Formula
- C53H62N10O10
- Formula Weight
- 999.14
- MOL File
- 2378258-52-5.mol
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PROTAC K-Ras Degrader-1 Property
- Density
- 1.40±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: 33.33 mg/mL (33.36 mM)
- pka
- 10.74±0.40(Predicted)
- form
- Solid
- color
- Light yellow to yellow
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-0106329
- Product name
- PROTACK-RasDegrader-1
- Purity
- 98.05%
- Packaging
- 1mg
- Price
- $550
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0106329
- Product name
- PROTACK-RasDegrader-1
- Purity
- 98.05%
- Packaging
- 5mg
- Price
- $1500
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0106329
- Product name
- PROTACK-RasDegrader-1
- Purity
- 98.05%
- Packaging
- 10mg
- Price
- $2500
- Updated
- 2021/12/16
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PROTAC K-Ras Degrader-1 Chemical Properties,Usage,Production
Description
PROTAC K-Ras Degrader-1 (Compound 518) is potent K-Ras degrader based PROTAC, exhibits ≥70% degradation efficacy in SW1573 cells[1].
References
[1]. CREW, Andrew P., et al. MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE. WO2019195609A2.
PROTAC K-Ras Degrader-1 Preparation Products And Raw materials
Raw materials
Preparation Products
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PROTAC K-Ras Degrader-1 Suppliers
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