3-(Chloromethyl)benzoic acid
- Product Name
- 3-(Chloromethyl)benzoic acid
- CAS No.
- 31719-77-4
- Chemical Name
- 3-(Chloromethyl)benzoic acid
- Synonyms
- NSC 49611;α-chloro-m-toluic acid;3-(Chloromethyl)Benzoic;Bedaquiline Impurity 106;m-Chloromethylbenzoic acid;ALPHA-CHLORO-M-TOLUIC ACID;3-(CHLOROMETHYL)BENZOIC ACID;Benzoic acid, 3-(chloromethyl)-;3-(CHLOROMETHYL) BENZOIC ACID 98%;3-(Chloromethyl)benzoic acid 31719-77-4
- CBNumber
- CB2335106
- Molecular Formula
- C8H7ClO2
- Formula Weight
- 170.59
- MOL File
- 31719-77-4.mol
3-(Chloromethyl)benzoic acid Property
- Melting point:
- 136-138 °C (lit.)
- Boiling point:
- 327.2±25.0 °C(Predicted)
- Density
- 1.315±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- methanol: 20 mg/mL, clear
- pka
- 4.09±0.10(Predicted)
- form
- solid
- color
- White
- BRN
- 637114
- CAS DataBase Reference
- 31719-77-4(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,C
- Risk Statements
- 36/37/38-34-20/21/22
- Safety Statements
- 26-36-45-36/37/39
- RIDADR
- UN 2811 6.1/PG 3
- WGK Germany
- 3
- F
- 19
- HazardClass
- 8
- PackingGroup
- Ⅱ
- HS Code
- 2916399090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 424315
- Product name
- 3-(Chloromethyl)benzoic acid
- Purity
- 97%
- Packaging
- 5g
- Price
- $23.2
- Updated
- 2025/07/31
- Product number
- 424315
- Product name
- 3-(Chloromethyl)benzoic acid
- Purity
- 97%
- Packaging
- 25g
- Price
- $70.7
- Updated
- 2025/07/31
- Product number
- C369100
- Product name
- 3-(Chloromethyl)benzoic acid
- Packaging
- 2g
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 2721-5-X1
- Product name
- 3-(Chloromethyl)benzoic acid
- Packaging
- 5G
- Price
- $56
- Updated
- 2021/12/16
- Product number
- L370
- Product name
- 3-(Chloromethyl)benzoic acid
- Packaging
- 5g
- Price
- $14
- Updated
- 2021/12/16
3-(Chloromethyl)benzoic acid Chemical Properties,Usage,Production
Uses
3-(Chloromethyl)benzoic acid is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff fields.
General Description
3-(Chloromethyl)benzoic acid (m-Chloromethylbenzoic acid) is a meta-substituted benzoic acid derivative. Correlations between Hammett substituent constants and calculated dipole moments and molecular transform and normalized molecular moment structure indices for m-chloromethylbenzoic acid was investigated. Hammett constants were observed to be linearly related only to the normalized charge moment index.
Synthesis
50-00-0
98-88-4
31719-77-4
The general procedure for the synthesis of 3-(chloromethyl)benzoic acid from formaldehyde and benzoyl chloride was as follows: 50 mL of chloroform and 20 mL of carbon tetrachloride were added to an autoclave. Subsequently, 0.1 mol of benzoyl chloride, 0.13 mol of paraformaldehyde and 0.02 mol of anhydrous manganese dichloride were added to it and nitrogen was charged to a pressure of 0.5 MPa. The reaction mixture was allowed to react at a constant temperature of 40-50 °C for 12 h. After the reaction was completed, the mixture was cooled down to a temperature of 0.5 °C. The reaction was carried out at a temperature of 0.5 °C. Upon completion of the reaction, the mixture was cooled to room temperature and the nitrogen was slowly released. The reaction solution was poured into 100 mL of ice water, stirred for 0.5 h, and left to stratify. The organic layer was concentrated under reduced pressure to give the crude product. A portion of the crude product was taken and analyzed by HPLC, which showed that the crude product contained 0.5% benzoic acid and 95.6% 3-(chloromethyl)benzoic acid.
References
[1] Patent: CN105384620, 2016, A. Location in patent: Paragraph 0038; 0039
3-(Chloromethyl)benzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
3-(Chloromethyl)benzoic acid Suppliers
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View Lastest Price from 3-(Chloromethyl)benzoic acid manufacturers
- Product
- 3-(Chloromethyl)benzoic acid 31719-77-4
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-29
- Product
- 3-(Chloromethyl)benzoic acid 31719-77-4
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-10-29
- Product
- 3-(Chloromethyl)benzoic acid 31719-77-4
- Price
- US $1.00/Kg
- Min. Order
- 1Kg
- Purity
- 98%
- Supply Ability
- 20T
- Release date
- 2024-07-21