ChemicalBook > CAS DataBase List > 4-Aminobenzotrifluoride

4-Aminobenzotrifluoride

Product Name
4-Aminobenzotrifluoride
CAS No.
455-14-1
Chemical Name
4-Aminobenzotrifluoride
Synonyms
4-(TRIFLUOROMETHYL)ANILINE;aminobenzotrifluoride;-trifluoromethylaniline;4-(Trifluoromethyl)benzenamine;TIMTEC-BB SBB003956;TRIFLUOROMETHYLANILINE;4-aminobenzotrifluride;4-AMINOBENZOTRIFLUORIDE;P-AMINOBENZOTRIFLUORIDE;4-aminotrifluorotoluene
CBNumber
CB2395593
Molecular Formula
C7H6F3N
Formula Weight
161.12
MOL File
455-14-1.mol
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4-Aminobenzotrifluoride Property

Melting point:
3-8 °C
Boiling point:
83 °C12 mm Hg(lit.)
Density 
1.283 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.483(lit.)
Flash point:
188 °F
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Liquid
pka
2.45(at 25℃)
Specific Gravity
1.283
color 
Clear colorless to yellow
Water Solubility 
<0.1 g/100 mL
Sensitive 
Air Sensitive
BRN 
1564853
InChIKey
ODGIMMLDVSWADK-UHFFFAOYSA-N
LogP
1.95 at 20℃
CAS DataBase Reference
455-14-1(CAS DataBase Reference)
NIST Chemistry Reference
Benzenamine, 4-(trifluoromethyl)-(455-14-1)
EPA Substance Registry System
4-(Trifluoromethyl)aniline (455-14-1)
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Safety

Hazard Codes 
T,N,Xi,Xn
Risk Statements 
25-36-50/53-36/37/38-33-20/21/22
Safety Statements 
26-45-60-61-36/37/39-36
RIDADR 
UN 2810 6.1/PG 3
WGK Germany 
3
RTECS 
XU9260000
Hazard Note 
Toxic/Irritant
TSCA 
T
HazardClass 
6.1
PackingGroup 
III
HS Code 
29214300
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H318Causes serious eye damage

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
224936
Product name
4-(Trifluoromethyl)aniline
Purity
99%
Packaging
1g
Price
$76.7
Updated
2024/03/01
Sigma-Aldrich
Product number
1357045
Product name
Leflunomide Related Compound A
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
100mg
Price
$596
Updated
2024/03/01
TCI Chemical
Product number
A0662
Product name
4-Aminobenzotrifluoride
Purity
>98.0%(GC)(T)
Packaging
25mL
Price
$46
Updated
2024/03/01
TCI Chemical
Product number
A0662
Product name
4-Aminobenzotrifluoride
Purity
>98.0%(GC)(T)
Packaging
100mL
Price
$158
Updated
2024/03/01
Sigma-Aldrich
Product number
Y0000487
Product name
Leflunomide impurity A
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
y0000487
Price
$223
Updated
2024/03/01
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4-Aminobenzotrifluoride Chemical Properties,Usage,Production

Chemical Properties

clear colorless to yellow liquid

Uses

4-Substituted aniline derivatives exert special hematotoxicity on the red blood cells and induce leukocytosis.

Uses

4-(Trifluoromethyl)aniline was used in the synthesis of 4-(trialkylmethyl)anilines. It was also used as a synthetic building block.

Definition

ChEBI: A substituted aniline that is a benzene ring substituted with an amino group at position 1 and a trifluoromethyl group at position 4.

Synthesis Reference(s)

The Journal of Organic Chemistry, 54, p. 2873, 1989 DOI: 10.1021/jo00273a020

General Description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

4-Aminobenzotrifluoride Preparation Products And Raw materials

Raw materials

nitrotoluene SODIUM HYPOBROMITE 4-Chlorobenzaldehyde Sodium bromide Phenyl isocyanate Stannous chloride 4-Nitrotoluene Benzotrichloride PHOSGENE FORMANILIDE Hydrogen fluoride p-Toluidine 4-Chlorobenzotrifluoride

Preparation Products

2-CHLORO-4-(TRIFLUOROMETHYL)BENZENESULFONYL CHLORIDE Leflunomide 4-TRIFLUOROMETHYL-N-METHYLANILINE 97 ETHYL 4-HYDROXY-6-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLATE 4-Amino-3,5-dichlorobenzotrifluoride ETHYL 4-CHLORO-6-(TRIFLUOROMETHYL)-3-QUINOLINECARBOXYLATE 2,6-BIS(TRIFLUOROMETHYL)-4-HYDROXYQUINOLINE
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4-Aminobenzotrifluoride Suppliers

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View Lastest Price from 4-Aminobenzotrifluoride manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
4-Aminobenzotrifluoride 455-14-1
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-25
Hebei Weibang Biotechnology Co., Ltd
Product
4-Aminobenzotrifluoride 455-14-1
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-31
Hebei Yanxi Chemical Co., Ltd.
Product
4-Aminobenzotrifluoride 455-14-1
Price
US $50.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10000
Release date
2023-11-01

455-14-1, 4-AminobenzotrifluorideRelated Search:

3-(Trifluoromethyl)benzaldehyde p-Toluidine 4-(Trifluoromethoxy)aniline N,N-Dimethylaniline 4-(Trifluoromethyl)cinnamic acid 4'-(Trifluoromethyl)acetophenone 4-Fluoroaniline 2,5-Bis(trifluoromethyl)aniline N-Methylaniline Acid Blue 93 Aniline 4-(Trifluoromethylthio)aniline N,N-Dimethyl-1,4-phenylenediamine 4'-(Octyloxy)-4-biphenylcarbonitrile 4-Trifluoromethylphenol 4-(Trifluoromethoxy)benzoic acid 4-(Trifluoromethoxy)benzyl chloride 4-(Trifluoromethyl)phenylacetic acid

  • TIMTEC-BB SBB003956
  • P-(TRIFLUOROMETHYL)ANILINE
  • P-AMINOBENZOTRIFLUORIDE
  • 1-AMINO-4-(TRIFLUOROMETHYL)BENZENE
  • 4-(TRIFLUOROMETHYL)ANILINE
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  • A,A,A-TRIFLUORO-P-TOLUIDINE
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  • 4-Aminobenzotrifluororide
  • 4-aminotrifluorotoluene
  • alpha,alpha,alpha-trifluoro-p-toluidin
  • aminobenzotrifluoride
  • Aniline, p-(trifluoromethyl)-
  • p-Amino-alpha,alpha,alpha-trifluorotoluene
  • p-Toluidine, alpha,alpha,alpha-trifluoro-
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  • 4-(Trifluoromethyl)aniline, 97+%
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  • 4-(Trifluoromethyl)phenylamine
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