ChemicalBook > CAS DataBase List > BISINDOLYLMALEIMIDE II

BISINDOLYLMALEIMIDE II

Product Name
BISINDOLYLMALEIMIDE II
CAS No.
137592-45-1
Chemical Name
BISINDOLYLMALEIMIDE II
Synonyms
BISINDOLYLMALEIMIDE II;Bisindolylmaleimide II, PKC inhibitor;2-[1-[2-(1-METHYLPYRROLIDINO)ETHYL]-1H-INDOL-3-YL]-3-(1H-INDOL-3-YL)MALEIMIDE;3-(1H-indol-3-yl)-4-[1-[2-(1-methylpyrrolidin-2-yl)ethyl]indol-3-yl]pyrrole-2,5-dione;3-(1H-Indol-3-yl)-4-[1-[2-(1-methyl-2-pyrrolidinyl)ethyl]-1H-indol-3-yl]-1H-pyrrole-2,5-dione;1H-Pyrrole-2,5-dione, 3-(1H-indol-3-yl)-4-[1-[2-(1-methyl-2-pyrrolidinyl)ethyl]-1H-indol-3-yl]-
CBNumber
CB2458955
Molecular Formula
C27H26N4O2
Formula Weight
438.52
MOL File
Mol file
More
Less

BISINDOLYLMALEIMIDE II Property

Boiling point:
709.9±60.0 °C(Predicted)
Density 
1.36±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
DMSO: soluble
form 
solid
pka
8.17±0.60(Predicted)
color 
Yellow to orange
More
Less

Safety

WGK Germany 
3
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
11020
Product name
Bisindolylmaleimide II
Purity
≥97% (isomer mixture)
Packaging
1mg
Price
$57
Updated
2024/03/01
Cayman Chemical
Product number
11020
Product name
Bisindolylmaleimide II
Purity
≥97% (isomer mixture)
Packaging
5mg
Price
$172
Updated
2024/03/01
Tocris
Product number
4128
Product name
BisindolylmaleimideII
Purity
≥97%(HPLC)
Packaging
10
Price
$216
Updated
2021/12/16
Tocris
Product number
4128
Product name
BisindolylmaleimideII
Purity
≥97%(HPLC)
Packaging
50
Price
$887
Updated
2021/12/16
TRC
Product number
B448535
Product name
BisindolylmaleimideII
Packaging
10mg
Price
$150
Updated
2021/12/16
More
Less

BISINDOLYLMALEIMIDE II Chemical Properties,Usage,Production

Uses

Bisindolylmaleimide II, is a potent ATP-competitive protein kinase C (PKC) inhibitor. In addition it inhibits PDK1 (IC50 = 14 μM), an important kinase in the insulin signaling pathway, and PKA (IC50 = 2.94 μM).

storage

-20°C

BISINDOLYLMALEIMIDE II Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

BISINDOLYLMALEIMIDE II Suppliers

CHINA 14 Japan 1 Switzerland 2 United Kingdom 3 United States 11 USA 1 Global 32

137592-45-1, BISINDOLYLMALEIMIDE IIRelated Search:

GO 6983 CALPHOSTIN C H-ARG-PHE-ALA-ARG-LYS-GLY-ALA-LEU-ARG-GLN-LYS-ASN-VAL-HIS-GLU-VAL-LYS-ASN-OH Ingenol Phloretin 1-O-HEXADECYL-2-O-ACETYL-SN-GLYCEROL CHELERYTHRINE CHLORIDE H-7 DIHYDROCHLORIDE K-252B K-252C Bisindolylmaleimide VIII acetate salt Hypericin GO 6976 D-ERYTHRO-SPHINGOSINE GF109203X GANGLIOSIDE GD1A DISODIUM SALT 2,2',3,3',4,4'-hexahydroxy-1,1'-biphenyl-6,6'-dimethanol dimethyl ether BISINDOLYLMALEIMIDE VII

  • BISINDOLYLMALEIMIDE II
  • 3-(1H-Indol-3-yl)-4-[1-[2-(1-methyl-2-pyrrolidinyl)ethyl]-1H-indol-3-yl]-1H-pyrrole-2,5-dione
  • 2-[1-[2-(1-METHYLPYRROLIDINO)ETHYL]-1H-INDOL-3-YL]-3-(1H-INDOL-3-YL)MALEIMIDE
  • 3-(1H-indol-3-yl)-4-[1-[2-(1-methylpyrrolidin-2-yl)ethyl]indol-3-yl]pyrrole-2,5-dione
  • 1H-Pyrrole-2,5-dione, 3-(1H-indol-3-yl)-4-[1-[2-(1-methyl-2-pyrrolidinyl)ethyl]-1H-indol-3-yl]-
  • Bisindolylmaleimide II, PKC inhibitor
  • 137592-45-1
  • Cell Signaling and Neuroscience
  • Cell Biology
  • BioChemical
  • Serine/Threonine Kinase Inhibitors
  • Kinase/Phosphatase Biology
  • Protein Kinase C (PKC)
  • Enzyme Inhibitors by Enzyme
  • Kinase/Phosphatase Biology
  • P to
  • Protein Kinase C (PKC)Cell Signaling and Neuroscience
  • Protein kinase CSerine/Threonine Kinase Biology
  • Protein Kinase Inhibitors
  • Protein Kinase InhibitorsPeptides for Cell Biology
  • Protein Kinase Related Peptides
  • Serine/Threonine Kinase Inhibitors