ChemicalBook > CAS DataBase List > Difluoroacetic acid

Difluoroacetic acid

Product Name
Difluoroacetic acid
CAS No.
381-73-7
Chemical Name
Difluoroacetic acid
Synonyms
2,2-DIFLUOROACETIC ACID;DIFLUOROACETATE;ifluoroaceticaci;difluoro-aceticaci;VITAS-BB TBB000649;DIFLUOROACETIC ACID;Difluoroaceticacid98%;Acetic acid, difluoro-;1,1-DIFLUOROACETIC ACID;Twotrifluoroacetic acid
CBNumber
CB2700577
Molecular Formula
C2H2F2O2
Formula Weight
96.03
MOL File
381-73-7.mol
More
Less

Difluoroacetic acid Property

Melting point:
-1 °C (lit.)
Boiling point:
132-134 °C (lit.)
Density 
1.526 g/mL at 25 °C (lit.)
vapor pressure 
11.7hPa at 25℃
refractive index 
n20/D 1.344(lit.)
Flash point:
174 °F
storage temp. 
2-8°C
solubility 
540.54g/L in organic solvents at 20 ℃
form 
Liquid
pka
pK1:1.33 (25°C)
color 
Clear colorless to light brown
Specific Gravity
1.527 (20℃)
Water Solubility 
1000g/L at 37℃
BRN 
1098588
InChIKey
PBWZKZYHONABLN-UHFFFAOYSA-N
LogP
0.601 at 37℃
CAS DataBase Reference
381-73-7(CAS DataBase Reference)
NIST Chemistry Reference
Difluoroacetic acid(381-73-7)
EPA Substance Registry System
Acetic acid, difluoro- (381-73-7)
More
Less

Safety

Hazard Codes 
C
Risk Statements 
34-35
Safety Statements 
26-36/37/39-45
RIDADR 
UN 3265 8/PG 2
WGK Germany 
3
RTECS 
AG9900000
Hazard Note 
Corrosive
TSCA 
T
HazardClass 
8
PackingGroup 
II
HS Code 
29159080
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

H332Harmful if inhaled

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
142859
Product name
Difluoroacetic acid
Purity
98%
Packaging
5g
Price
$78.8
Updated
2024/03/01
Sigma-Aldrich
Product number
142859
Product name
Difluoroacetic acid
Purity
98%
Packaging
25g
Price
$191
Updated
2024/03/01
Sigma-Aldrich
Product number
00922
Product name
Difluoroacetic acid
Purity
for LC-MS LiChropur?, ≥97.5% (GC)
Packaging
10X1ML
Price
$252
Updated
2022/05/15
Sigma-Aldrich
Product number
00922
Product name
Difluoroacetic acid
Purity
for LC-MS LiChropur?, ≥97.5% (GC)
Packaging
50ML
Price
$802
Updated
2022/05/15
TCI Chemical
Product number
D1423
Product name
Difluoroacetic Acid
Purity
>97.0%(T)
Packaging
5g
Price
$50
Updated
2024/03/01
More
Less

Difluoroacetic acid Chemical Properties,Usage,Production

Chemical Properties

clear colorless to light brown liquid

Uses

Used in the preparation of 2-difluoromethylbenzimidazoles, -oxazoles and -thiazoles from ortho-substituted anilines mediated by triphenylphoshine.

Definition

ChEBI: A monocarboxylic acid that is acetic acid in which two of the methyl hydrogens are substituted by fluorines.

Flammability and Explosibility

Non flammable

Purification Methods

Purify the acid by distilling over P2O5. The acid chloride is a fuming liquid b 25o/atm, and the amide has b 108.6o/35mm, m 52o (from *C6H6), and the anilide has b 90o/1mm, 114o/5mm, m 58o [Henne & Pelley J Am Chem Soc 74 1426 1952, Coffman et al. J Org Chem 14 749 1949, NMR: Meyer et al. J Am Chem Soc 75 4567 1953, pK: Wegscheider Z Phys Chem 69 614 1909]. [Beilstein 2 IV 455.]

Difluoroacetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Difluoroacetic acid Suppliers

Americas 1 Belgium 2 Brazil 1 CHINA 264 Europe 4 France 1 Germany 5 India 17 Ireland 1 Japan 7 Jordan 1 Russia 3 Slovakia 1 South Korea 2 Switzerland 2 The Netherlands 1 Ukraine 1 United Kingdom 17 United States 36 Global 367
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Wilshire Technologies, Inc.
Tel
--
Fax
--
Email
info@wilshiretechnologies.com
Country
United States
ProdList
893
Advantage
58
SynQuest Laboratories, Inc. (Part of Central Glass Co., Ltd.)
Tel
--
Fax
--
Email
nfo@synquestlabs.com
Country
United States
ProdList
1897
Advantage
58
SynQuest Laboratories, Inc.,
Tel
--
Fax
--
Country
United States
ProdList
2301
Advantage
58
Barath Biosciences, Inc.
Tel
--
Fax
--
Email
barath@barathbiosciences.com
Country
United States
ProdList
203
Advantage
58
Alichem Inc.
Tel
--
Fax
--
Email
sales@alichem.com
Country
United States
ProdList
6167
Advantage
58
SynQuest Laboratories, Inc.
Tel
--
Fax
--
Email
info@synquestlabs.com
Country
United States
ProdList
6871
Advantage
62
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
TCI America
Tel
--
Fax
--
Email
sales@tciamerica.com
Country
United States
ProdList
6909
Advantage
75
Frontier Scientific, Inc.
Tel
--
Fax
--
Email
sales@frontiersci.com
Country
United States
ProdList
6222
Advantage
86
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
Ivy Fine Chemicals
Tel
--
Fax
--
Email
sales@ivychem.com
Country
United States
ProdList
6493
Advantage
58
Wilshire Chemical Company Inc.
Tel
--
Fax
--
Email
WilshrChem@AOL.COM
Country
United States
ProdList
3498
Advantage
58
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6962
Advantage
56
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
ChemService Inc.
Tel
--
Fax
--
Country
United States
ProdList
6379
Advantage
68
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
Oakwood Products, Inc.
Tel
--
Fax
--
Email
sales@oakwoodchemical.com
Country
United States
ProdList
6193
Advantage
74
Narchem Corporation
Tel
--
Fax
--
Email
sales@narchem.com
Country
United States
ProdList
2813
Advantage
60
HONEST JOY HOLDINGS LIMITED
Tel
--
Fax
--
Email
sales@honestjoy.cn
Country
United States
ProdList
6675
Advantage
54
Advanced Synthesis Technologies
Tel
--
Fax
--
Email
sales@advancedsynthesis.com
Country
United States
ProdList
4775
Advantage
61
2A PharmaChem USA
Tel
--
Fax
--
Email
sales@2apharmachem.com
Country
United States
ProdList
6137
Advantage
39
City Chemical LLC
Tel
--
Fax
--
Email
sales@citychemical.com
Country
United States
ProdList
6708
Advantage
72
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
AK Scientific, Inc.
Tel
--
Fax
--
Email
sales@aksci.com
Country
United States
ProdList
6347
Advantage
65
APAC Pharmaceutical, LLC
Tel
--
Fax
--
Email
sales@apacpharma.com
Country
United States
ProdList
6322
Advantage
38
American Custom Chemicals Corporation
Tel
--
Fax
--
Email
sales@acccorporation.com
Country
United States
ProdList
6820
Advantage
51
Advance Scientific & Chemical
Tel
--
Fax
--
Email
sales@advance-scientific.com
Country
United States
ProdList
6419
Advantage
71
ASDI Incorporated
Tel
--
Fax
--
Email
customerservice@asdi.net
Country
United States
ProdList
6922
Advantage
67
ChemPacific Corporation
Tel
--
Fax
--
Email
sales@chempacific.com
Country
United States
ProdList
6891
Advantage
51
Pfaltz & Bauer, Inc.
Tel
--
Fax
--
Email
sales@pfaltzandbauer.com
Country
United States
ProdList
6828
Advantage
72
GFS Chemicals
Tel
--
Fax
--
Email
gfschem@gfschemicals.com
Country
United States
ProdList
3403
Advantage
75
MP Biomedicals, Inc.
Tel
--
Fax
--
Country
United States
ProdList
6561
Advantage
81
City Chemicals Corporation
Tel
--
Fax
--
Country
United States
ProdList
6460
Advantage
72
Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
United States
ProdList
6814
Advantage
81
More
Less

View Lastest Price from Difluoroacetic acid manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
Difluoroacetic acid 381-73-7
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2024-11-22
Zibo Hangyu Biotechnology Development Co., Ltd
Product
Difluoroacetic acid 381-73-7
Price
US $90.00-900.00/kg
Min. Order
10kg
Purity
0.99
Supply Ability
20tons
Release date
2023-11-08
Hefei TNJ Chemical Industry Co.,Ltd.
Product
Difluoroacetic Acid 381-73-7
Price
US $0.00/L
Min. Order
200L
Purity
99%
Supply Ability
1000MT
Release date
2019-03-08

381-73-7, Difluoroacetic acidRelated Search:

Ethyl 2-(Chlorosulfonyl)acetate 2-Bromo-2,2-difluoroacetic acid ethyl ester Glycine Folic acid Trifluoroacetic acid Trifluoroacetic anhydride DIFLUOROACETIC ACID ETHYL ESTER,ETHYL DIFLUOROACETIC ACID Fluroxypyr DIFLUOROACETIC ACID METHYL ESTER,α,2-Difluoroacetic acid methyl ester Ethyl trifluoroacetate Citric acid Chlorodifluoroacetic acid ethyl ester Sodium chlorodifluoroacetate Diethyl 2,2-difluoromalonate Ascoric Acid DIFLUOROACETIC ACID ANHYDRIDE TRIMETHYLSILYL TRIFLUOROACETATE THALLIUM(III) TRIFLUOROACETATE

  • 2,2-DIFLUOROACETIC ACID
  • 1,1-DIFLUOROACETIC ACID
  • VITAS-BB TBB000649
  • DIFLUOROACETIC ACID
  • Acetic acid, difluoro-
  • difluoro-aceticaci
  • DIFLUOROACETATE
  • Difluoroaceticacid98%
  • Difluoroacetic acid, 98% 10ML
  • Difluoroacetic acid, 98% 2.5ML
  • 2,2-Difluoroethanoic acid
  • Twotrifluoroacetic acid
  • Aceticacid, 2,2-difluoro-
  • Difluoroacetic acid, 97%+
  • Difluoroacetic Acid &gt
  • ifluoroaceticaci
  • 381-73-7
  • 7381-73-7
  • F2CHCO2H
  • F2CHCOOH
  • CHF2COOH
  • C2H2F2O2
  • CARBOXYLIC ACID
  • Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds
  • Fluorinated Building Blocks
  • Synthetic Reagents
  • Organic Acids
  • Pharmaceutical Intermediates
  • Small molecule
  • Organic Fluorides
  • Fluorinated Building Blocks
  • Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds
  • Synthetic Organic Chemistry
  • Chemical Synthesis
  • Organic Acids
  • Synthetic Reagents