D-Proline

Product Name: D-Proline
CAS No.: 344-25-2
Chemical Name: D-Proline
Synonyms: Proline;H-D-PRO-OH;D-PRO;D-Pro-OH;(R)-PYRROLIDINE-2-CARBOXYLIC ACID;(2R)-Pyrrolidine-2-carboxylic acid;D-PYRROLIDINE-2-CARBOXYLIC ACID;D-PyrroL;D-PROLINE;D(+)-PROLINE
CBNumber: CB2754303
Molecular Formula: C5H9NO2
Formula Weight: 115.13
MOL File: 344-25-2.mol

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D-Proline Property

Melting point:: 223 °C (dec.) (lit.)
alpha: 84.75 º (c=4, H2O)
Boiling point:: 215.41°C (rough estimate)
Density: 1.36
refractive index: 85 ° (C=4, H2O)
storage temp.: Inert atmosphere,Room Temperature
solubility: Methanol (Slightly), Water (Sparingly)
form: Powder
pka: 1.952(at 25℃)
color: White to yellow to pale brown
optical activity: [α]22/D +85.0°, c = 4 in H2O
Water Solubility: soluble >1000 g/L (20 ºC)
Sensitive: Hygroscopic
BRN: 80811
InChIKey: ONIBWKKTOPOVIA-SCSAIBSYSA-N
LogP: -0.060 (est)
CAS DataBase Reference: 344-25-2(CAS DataBase Reference)
EPA Substance Registry System: D-Proline (344-25-2)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 22-36/37/38
Safety Statements: 22-24/25-36/37/39-26
WGK Germany: 3
F: 3-10
Hazard Note: Irritant
TSCA: Yes
HS Code: 29339990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 858919
Product name: D-Proline
Purity: ReagentPlus , ≥99%
Packaging: 500mg
Price: $46.7
Updated: 2024/03/01

Sigma-Aldrich

Product number: 858919
Product name: D-Proline
Purity: ReagentPlus , ≥99%
Packaging: 5g
Price: $114
Updated: 2024/03/01

TCI Chemical

Product number: P0994
Product name: D-Proline
Purity: >98.0%(T)
Packaging: 5g
Price: $76
Updated: 2024/03/01

TCI Chemical

Product number: P0994
Product name: D-Proline
Purity: >98.0%(T)
Packaging: 25g
Price: $242
Updated: 2024/03/01

Alfa Aesar

Product number: A10682
Product name: D-Proline, 99%
Packaging: 1g
Price: $42.65
Updated: 2024/03/01

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D-Proline Chemical Properties,Usage,Production

Chemical Properties

White to off-white powder

Occurrence

D-proline is an isomer of the naturally occurring amino acid, L-Proline. D-amino acids have been found in relatively high abundance in human plasma and saliva. These amino acids may be of bacterial origin, but there is also evidence that they are endogenously produced through amino acid racemase activity.

Uses

Used in the synthesis of (R)-(+)-N-Boc-Pipecolic Acid, (S)-(-)-Coniine, (S)-(+)-Pelletierine, (+)-.beta.-Conhydrine, and (S)-(-)-Ropivacaine and formal synthesis of (-)-Lasubine II and (+)-Cermizine C.

Uses

Labelled D-Proline Lasubine II and (+)-Cermizine C.

Uses

proline is a skin-conditioning agent. An amino acid found in the collagen molecule.

Definition

ChEBI: D-proline is the D-enantiomer of proline. It has a role as a mouse metabolite. It is a D-alpha-amino acid and a proline. It is a conjugate base of a D-prolinium. It is a conjugate acid of a D-prolinate. It is an enantiomer of a L-proline. It is a tautomer of a D-proline zwitterion.

Synthesis Reference(s)

Journal of the American Chemical Society, 71, p. 2818, 1949 DOI: 10.1021/ja01176a065
Tetrahedron Letters, 28, p. 6469, 1987 DOI: 10.1016/S0040-4039(00)96890-4

D-Proline Preparation Products And Raw materials

Raw materials

L-Proline

Preparation Products

N-Boc-D-proline (1R,2R)-N-BOC-1-AMINO-2-PHENYLCYCLOPROPANECARBOXYLIC ACID

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D-Proline Suppliers

Americas 1 Austria 1 Belgium 4 Canada 5 CHINA 544 Europe 4 France 3 Germany 13 India 36 Japan 14 Poland 1 Slovakia 1 South Korea 2 Switzerland 9 United Kingdom 21 United States 74 USA 1 Global 734

Fisher Scientific Uk Ltd.

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Whyte Chemicals

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Apollo Scientific Ltd.

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Tokyo Chemical Industry UK Ltd.

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Carbosynth Limited

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Molekula Ltd

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Leancare Ltd.

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Manchester Organics

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CARBONE SCIENTIFIC CO.,LTD

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MOLEKULA Ltd.

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ETA SCIENTIFIC Co.,Ltd

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UK GREEN SCIENTIFIC CO.,LIMITED

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Eurolabs Limited

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Fluorochem Ltd

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Fluorochem Ltd.

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VWR International

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View Lastest Price from D-Proline manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: D-Proline 344-25-2
Price: US $150.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 500kg
Release date: 2024-12-06

Hubei Lidu New Material Technology Co., Ltd

Product: D-Proline 344-25-2
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 20t
Release date: 2024-12-11

WUHAN FORTUNA CHEMICAL CO., LTD

Product: D-Proline 344-25-2
Price: US $0.00-0.00/Kg/Drum
Min. Order: 1KG
Purity: 98.5%-101%
Supply Ability: 500kg
Release date: 2021-06-02

344-25-2, D-ProlineRelated Search:

D-Tartaric acid D-Alanine D-Proline trans-4-Hydroxy-D-proline N-Benzyloxycarbonyl-D-proline cis-4-Hydroxy-D-proline Fmoc-D-proline BOC-D-PRO-OSU AC-D-PRO-OH (3S)-1-(tert-Butoxycarbonyl)-3-pyrrolidinecarboxylic acid Z-D-PYR-OH Methyl pyrrolidine-2-carboxylate hydrochloride D-Pyroglutamic acid Ethyl D-(-)-pyroglutamate Oxaceprol trans-4-Cyclohexyl-L-proline 1-(4-HYDROXY-PHENYL)-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID,1-(4-HYDROXY-PHENYL)-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID H-D-PRO-OTBU

D-Pro-OH

D-Proline≥ 99% (Assay)

D-Proline,99%e.e.

(R)-(+)-PROLINE

(R)-PYRROLIDINE-2-CARBOXYLIC ACID

D-2-PYRROLIDINECARBOXYLIC ACID

D-PYRROLIDINE-2-CARBOXYLIC ACID

D(+)-PROLINE

D-PROLINE

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(2R)-Pyrrolidine-2-carboxylic acid

D-PROLINE, 99+% (98% EE/GLC)

D-PyrroL

idine-2-carboxyL

Captopril Impurity 32

D-(+)-PROLINE ((R)-(+)-PROLINE)

D-PROLINE extrapure

D-Proline-d3

D-Proline, (2R)-2-Carboxypyrrolidine

D-Proline ReagentPlus(R), >=99%

D-Proline Vetec(TM) reagent grade, 98%

D-Proline&gt

D-Proline，98%

D-Proline USP/EP/BP

dextro-(+)-proline

D-Proline CAS No. 344-25-2

D-Proline extrapure CHR, 99%

D-Proline (9CI, ACI)

Captopril Impurity 38

(2R)-pyrrolidin-1-ium-2-carboxylate

344-25-2

24344-25-2

145-85-3

344-25-5

C5H9NO2

CARBOXYLIC ACID

Amino Acid Derivatives

Proline

Peptide Synthesis

Specialty Synthesis

Amino Acids and Derivatives

Proline [Pro, P]

Amino Acids and Derivatives

alpha-Amino Acids

Amino Acids

Biochemistry

Amino Acids & Derivatives

Heterocycles

Isotope Labelled Compounds

206-452-7

Amino ACIDS SERIES