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3-Amino-5-bromo-2-chloropyridine

Product Name
3-Amino-5-bromo-2-chloropyridine
CAS No.
588729-99-1
Chemical Name
3-Amino-5-bromo-2-chloropyridine
Synonyms
5-BROMO-2-CHLOROPYRIDIN-3-AMINE;2-Chloro-3-amino-5-bromopyridine;CAS:588729-99-1;5-BROMO-2-CHLOROPYRI;3-Amino-5-bromo-2-chL;3-AMino-5-broMo-2-chlorop...;3-Amino-5-Bromo-2-Chloropyrid ;3-Amino-5-bromo-2-chloropyridi;2-Chloro-3-ami-5-bromopyridine;5-BROMO-2-CHLORO-3-PYRIDINAMINE
CBNumber
CB3160952
Molecular Formula
C5H4BrClN2
Formula Weight
207.46
MOL File
588729-99-1.mol
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3-Amino-5-bromo-2-chloropyridine Property

Melting point:
129-132℃
Boiling point:
296.8±35.0 °C(Predicted)
Density 
1.834±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
powder to crystal
pka
0.03±0.10(Predicted)
color 
White to Orange to Green
λmax
314nm(EtOH)(lit.)
InChI
InChI=1S/C5H4BrClN2/c6-3-1-4(8)5(7)9-2-3/h1-2H,8H2
InChIKey
ZSEZSALOLWCCGT-UHFFFAOYSA-N
SMILES
C1(Cl)=NC=C(Br)C=C1N
CAS DataBase Reference
588729-99-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,T
Risk Statements 
25-37/38-41-22
Safety Statements 
26-39-45
RIDADR 
2811
WGK Germany 
3
HazardClass 
IRRITANT
PackingGroup 
Ⅲ
HS Code 
29333990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
720909
Product name
3-Amino-5-bromo-2-chloropyridine
Purity
97%
Packaging
5g
Price
$62.2
Updated
2023/06/20
TCI Chemical
Product number
A2540
Product name
3-Amino-5-bromo-2-chloropyridine
Purity
>98.0%(GC)
Packaging
5g
Price
$132
Updated
2025/07/31
TCI Chemical
Product number
A2540
Product name
3-Amino-5-bromo-2-chloropyridine
Purity
>98.0%(GC)
Packaging
25g
Price
$359
Updated
2024/03/01
TRC
Product number
A602038
Product name
3-Amino-5-bromo-2-chloropyridine
Packaging
1g
Price
$55
Updated
2021/12/16
Oakwood
Product number
033563
Product name
3-Amino-5-bromo-2-chloropyridine
Purity
98%
Packaging
25g
Price
$40
Updated
2021/12/16
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3-Amino-5-bromo-2-chloropyridine Chemical Properties,Usage,Production

Chemical Properties

Colorless solid

Uses

3-Amino-5-bromo-2-chloropyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Synthesis

67443-38-3

588729-99-1

Step 1: 2-Chloro-3-nitro-5-bromopyridine (2.38 g, 10 mmol) was dissolved in methanol (50 mL) and Raney nickel (0.5 g) was added. The reaction mixture was stirred overnight under hydrogen atmosphere. Upon completion of the reaction, the Raney nickel was removed by filtration and the filtrate was concentrated to afford 2-chloro-3-amino-5-bromopyridine (2.08 g, 100% yield), which could be used in subsequent reactions without further purification. Mass spectrum (ESI) m/z: 208.9 [M + 1].

References

[1] Patent: EP2952510, 2015, A1. Location in patent: Paragraph 0146
[2] Patent: WO2008/157191, 2008, A2. Location in patent: Page/Page column 75
[3] Patent: WO2008/150827, 2008, A1. Location in patent: Page/Page column 69
[4] Journal of Heterocyclic Chemistry, 2003, vol. 40, # 2, p. 261 - 268
[5] Patent: US2012/238587, 2012, A1. Location in patent: Page/Page column 17

3-Amino-5-bromo-2-chloropyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Amino-5-bromo-2-chloropyridine Suppliers

Americas 1 China 269 Europe 1 France 1 Germany 4 India 23 Japan 1 South Korea 1 United Kingdom 11 United States 49 Global 361
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View Lastest Price from 3-Amino-5-bromo-2-chloropyridine manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
3-Amino-5-bromo-2-chloropyridine 588729-99-1
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10000KGS
Release date
2025-05-29
Henan Fengda Chemical Co., Ltd
Product
3-Amino-5-bromo-2-chloropyridine 588729-99-1
Price
US $200.00-1.00/KG
Min. Order
1KG
Purity
99%, 99.5% Sublimated
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-30
Dideu Industries Group Limited
Product
2-Chloro-3-amino-5-bromopyridine 588729-99-1
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons min
Release date
2021-08-18

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