Psoralen

ChemicalBook > CAS DataBase List > Psoralen

Description References

Product Name: Psoralen
CAS No.: 66-97-7
Chemical Name: Psoralen
Synonyms: FICUSIN;Furocoumarin;Psoralene;Psoralea extract;7H-Furo[3,2-g]chromen-7-one;7H-FURO[3,2-G][1]BENZOPYRAN-7-ONE;PSORALEN;Prosuler;Psorline-P;NSC 404562
CBNumber: CB3181900
Molecular Formula: C11H6O3
Formula Weight: 186.16
MOL File: 66-97-7.mol

Less

Psoralen Property

Melting point:: 160-162 °C
Boiling point:: 280.64°C (rough estimate)
Density: 1.2477 (rough estimate)
refractive index: 1.6310 (estimate)
storage temp.: 2-8°C
solubility: Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form: Solid
color: White to Off-White
Water Solubility: 65.16mg/L(25 ºC)
λmax: 328nm(EtOH)(lit.)
Merck: 14,7928
BRN: 152784
InChIKey: ZCCUUQDIBDJBTK-UHFFFAOYSA-N
LogP: 1.670
CAS DataBase Reference: 66-97-7(CAS DataBase Reference)
NIST Chemistry Reference: 7H-furo[3,2-g][1]benzopyran-7-one(66-97-7)

Less

Safety

Hazard Codes: Xn
Risk Statements: 22-36/37/38
Safety Statements: 26
WGK Germany: 3
RTECS: LV0944000
F: 8-10
HS Code: 29339900
Hazardous Substances Data: 66-97-7(Hazardous Substances Data)

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: P8399
Product name: Psoralen
Purity: ≥99% (HPLC)
Packaging: 10mg
Price: $129
Updated: 2024/03/01

Sigma-Aldrich

Product number: 73633
Product name: Psoralen
Purity: analytical standard
Packaging: 10mg
Price: $508
Updated: 2022/05/15

TCI Chemical

Product number: P2077
Product name: Psoralen
Purity: >99.0%(GC)
Packaging: 20mg
Price: $70
Updated: 2024/03/01

TCI Chemical

Product number: P2077
Product name: Psoralen
Purity: >99.0%(GC)
Packaging: 100mg
Price: $209
Updated: 2024/03/01

Alfa Aesar

Product number: J60042
Product name: Psoralen, 97%
Packaging: 100mg
Price: $241.65
Updated: 2024/03/01

Less

Psoralen Chemical Properties,Usage,Production

Description

Psoralen is a kind of naturally occurring furocoumarin. It is naturally occurred in the seeds of Psoralea corylifolia as well as in the common fig, celery, parsley, West Indian Satinwood and all citrus fruits. It is capable of binding to DNA via single- and double-strand cross-linking upon photoactivation with UV radiation. It can intercalate with DNA, blocking its synthesis and cell division. For this reason, it is an important mutagen and can be used in related molecular biology studies. It also exhibits anti- proliferative, anti-allergenic and anti-histamine functions. It can also be used in PUVA treatment for skin diseases such as psoriasis, eczema and vitiligo. It is also effective tanning activator in sunscreens. Some of its derivatives, e.g. amino-psoralen, amotosalen HCl, can even inactivate pathogens in blood products.

References

https://en.wikipedia.org/wiki/Psoralen
https://pubchem.ncbi.nlm.nih.gov/compound/Psoralen#section=Top

Chemical Properties

Crystalline Solid

Uses

Use as photochemical probe in biological systems

Uses

Psoralens are phytoalexins; they are used by plants in a defensive response to attacks by fungi and insects. They have also shown photosensitizing and phototoxic effects in animals and humans and have been used in photochemotherapy for management of vitiligo, psoriasis, and mycosis fungoides. Used as photochemical probe in biological systems.

Uses

As photochemical probe in biological systems: P.-S. Song, C.-N. Ou, Ann. N.Y. Acad. Sci. 346, 355 (1980).

Definition

ChEBI: The simplest member of the class of psoralens that is 7H-furo[3,2-g]chromene having a keto group at position 7. It has been found in plants like Psoralea corylifolia and Ficus salicifolia.

Synthesis Reference(s)

Journal of the American Chemical Society, 106, p. 6735, 1984 DOI: 10.1021/ja00334a044
Synthetic Communications, 37, p. 63, 2007 DOI: 10.1080/00397910600978093

Biochem/physiol Actions

Psoralen belongs to the linear type furanocoumarins. It intercalates and induces interstrand cross-links in DNA. On UV exposure psoralen is excited leading to irreversible intercalation with DNA by covalent bond formation. This property of psoralen ultraviolet A light (PUVA) is exploited in treating skin diseases and cutaneous T-cell lymphoma. However, usage psoralen also leads to hepatotoxicity and cytotoxicity by the generation of psoralen photoproducts (POPs). It may be useful in treating osteoporosis

Psoralen Preparation Products And Raw materials

Raw materials

Preparation Products

Less

Psoralen Suppliers

Canada 2 China 290 Czech Republic 1 Europe 1 France 3 Germany 4 India 12 Japan 1 Switzerland 2 Ukraine 1 United Kingdom 10 United States 45 USA 1 Global 373

Nanjing Spring & Autumn Biological Engineering Co., Ltd.

Tel: 025-84430028 13815430202
Email: sale02@cqherb.com
Country: China
ProdList: 289
Advantage: 59

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6005
Advantage: 61

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18736
Advantage: 57

Sichuan Kulinan Technology Co., Ltd

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11707
Advantage: 57

China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7811
Advantage: 57

Aktin Chemicals, Inc.

Tel: 86-28-85159085
Fax: 86-28-85152372
Email: info@aktinchem.com
Country: China
ProdList: 297
Advantage: 62

Shenzhen Sungening Bio-Tech Co., Ltd

Tel: +86-0755-89668383
Fax: +86-0755-89594066/4038
Email: sales@sungening.com
Country: China
ProdList: 1319
Advantage: 65

Hangzhou Yuhao Chemical Technology Co., Ltd

Tel: 0571-82693216
Fax: +86-571-82880190
Email: info@yuhaochemical.com
Country: China
ProdList: 9387
Advantage: 52

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: sales@meilune.com
Country: China
ProdList: 4728
Advantage: 58

BioBioPha Co., Ltd.

Tel: 0871-65217109 13211707573;
Fax: 0871-65215563
Email: y.liu@mail.biobiopha.com
Country: China
ProdList: 5653
Advantage: 65

ShangHai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847 13636370518
Fax: 021-55068248
Email: shyysw007@163.com
Country: China
ProdList: 4940
Advantage: 60

Chengdu Ai Keda Chemical Technology Co., Ltd.

Tel: 4008-755-333 18080918076
Fax: 028-86757656
Email: 800078821@qq.com
Country: China
ProdList: 9718
Advantage: 55

Chengdu Climax Biotech Co., Ltd.

Tel: 028-83311324 1278112614
Fax: 028-83311324
Email: climaxbiotech@gmail.com
Country: China
ProdList: 925
Advantage: 58

Beijing HuaMeiHuLiBiological Chemical

Tel: 010-56205725
Fax: 010-65763397
Email: waley188@sohu.com
Country: China
ProdList: 12335
Advantage: 58

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 22514
Advantage: 55

Suzhou NeuPharma Co., Ltd.

Tel: 0512-62956991
Fax: 0512-67062860
Email: sales@neupharma.com
Country: China
ProdList: 40
Advantage: 65

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 1316706386
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

The future of Shanghai Industrial Co., Ltd.

Tel: 021-61552785
Fax: 021-55660885
Email: sales@shshiji.com
Country: China
ProdList: 9545
Advantage: 55

Shanghai Ruji Biology Technology Co., Ltd.

Tel: +86-21-65211385-8001 36031160
Fax: +86-21-65211385-8004
Email: sales@shruji.com
Country: China
ProdList: 3224
Advantage: 55

Shanghai Tauto Biotech Co., Ltd.

Tel: 021-51320588
Fax: 0086-21-51320502
Email: tauto@tautobiotech.com
Country: China
ProdList: 3989
Advantage: 66

Guangzhou Isun Pharmaceutical Co., Ltd

Tel: 020-39119399 18927568969
Fax: 020-39119999
Email: isunpharm@qq.com
Country: China
ProdList: 4674
Advantage: 55

TargetMol Chemicals Inc.

Tel: 021-021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7783
Advantage: 58

Cheng Du Pufeide Biotechnology Co., Ltd.

Tel: 028-82610909 13388174823
Fax: 8171-1798
Email: scglp@glp-china.com
Country: China
ProdList: 1064
Advantage: 58

Chengdu Herbpurify Co.Ltd.

Tel: 18302802153 18981717076
Fax: 086-28-85377358
Email: 2851037746@qq.com
Country: China
ProdList: 1104
Advantage: 58

Shanghai BeiZhuo Biotech Co., Ltd.

Tel: 021-61119791,13386096464
Fax: 021-50190009
Email: bzswkf@foxmail.com
Country: China
ProdList: 3921
Advantage: 50

Shanghai Zhanshu Chemical Technology Co., Ltd

Tel: +86-21-58589556
Fax: +86-21-58589557
Country: China
ProdList: 413
Advantage: 55

Amatek Scientific Co. Ltd.

Tel: 0512-56316828 4008675858
Fax: +86-512-56316826
Email: sales@amateksci.com
Country: China
ProdList: 9893
Advantage: 55

Wuhan DKY Technology Co.,Ltd.

Tel: 027-27-81302488 15972195220
Fax: 027-81302088
Email: info@dkybpc.com
Country: China
ProdList: 1672
Advantage: 58

Vientiane Tianjin Hengyuan Technology Co., Ltd.

Tel: 15722085254
Fax: 022-26358246
Email: phytochemical@126.com
Country: China
ProdList: 813
Advantage: 55

Shanghai JONLN Reagent Co., Ltd.

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: 422131432@qq.com
Country: China
ProdList: 9978
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 41457
Advantage: 60

Chemwill Asia Co.,Ltd.

Tel: 86-21-51086038
Fax: 86-21-51861608
Country: China
ProdList: 2930
Advantage: 58

Hangzhou Trylead Chemical Technology Co.,LTD

Tel: 0571-87086220 13516718938
Fax: 0571-87012927
Email: zyf@trylead-chem.com
Country: China
ProdList: 305
Advantage: 64

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15178
Advantage: 58

Finetech Industry Limited

Tel: 027-87465837 19945049750
Fax: 027-8777-2287
Email: sales@finetechnology-ind.com
Country: China
ProdList: 9647
Advantage: 58

Shanghai Aspire Biological Technology Co., Ltd.

Tel: 021-61317773
Fax: 021-61486878
Email: sales@aspirebio.com
Country: China
ProdList: 2880
Advantage: 58

Shanghai Xingui Biotechnology Co., Ltd.

Tel: 17501653713
Email: xingui2022@126.com
Country: China
ProdList: 10003
Advantage: 58

Shanghai Macklin Biochemical Co.,Ltd.

Tel: 15221275939 15221275939
Fax: 021-50706099
Email: shenlinxing@macklin.cn
Country: China
ProdList: 16166
Advantage: 55

Hangzhou J&H Chemical Co., Ltd.

Tel: 0571-+86-571-87396432
Fax: 0571-87396431
Email: sales@jhechem.com
Country: China
ProdList: 11733
Advantage: 59

Shanghai Yongye Biotechnology Co., Ltd.

Tel: 86-021-61559134 15921386130
Fax: 021-55068248
Email: 3423497944@qq.com
Country: China
ProdList: 8144
Advantage: 55

Nanjing Duolong Bio-tech Co.,Ltd.

Tel: 18905173768
Fax: 025-83263139
Email: sales@dolonchem.com
Country: China
ProdList: 2331
Advantage: 50

AdooQ Bioscience CHINA

Tel: 025-58849295 18951903616;
Fax: 025-68650336
Email: info@adooq.cn
Country: China
ProdList: 2990
Advantage: 60

Hubei Jusheng Technology Co.,Ltd

Tel: 027-59599241 18871490274
Fax: 027-59599241
Email: 1400878000@qq.com
Country: China
ProdList: 9958
Advantage: 58

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51456
Advantage: 80

Watson Biotechnology Co.,Ltd

Tel: 027-59207879 1972026995 18140587686
Fax: QQ：1972026995
Email: sales@3600chem.com
Country: China
ProdList: 4656
Advantage: 55

Less

View Lastest Price from Psoralen manufacturers

BINBO BIOLOGICAL CO.,LTD

Product: Psoralen 66-97-7
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99.8%
Supply Ability: 1000 kg
Release date: 2024-04-16

Hebei Chuanghai Biotechnology Co,.LTD

Product: Psoralen 66-97-7
Price: US $10.70/kg
Min. Order: 10kg
Purity: 99%
Supply Ability: 10000kg
Release date: 2024-08-20

Hebei Kingfiner Technology Development Co.Ltd

Product: Psoralen 66-97-7
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 50000kg
Release date: 2024-05-21

66-97-7, PsoralenRelated Search:

Coumarin 2-Oxo-(2H)-furo(2,3-h)-1-benzopyran Psoralen-mop BAVACHIN Bergapten BERGAPTOL psoralen,4,5’,8-trimethyl Imperatorin Bergamotine OXYPEUCEDANIN ISOPIMPINELLIN 3-(HYDROXYMETHYL)-2,5,9-TRIMETHYL-7H-FURO[3,2-G][1]BENZOPYRAN-7-ONE ALLOISOIMPERATORIN XANTHOTOXOL Isoimperatorin BYAKANGELICIN 3-(alpha,alpha-dimethylallyl)psoralen 7H-Furo3,2-g1benzopyran-7-one, 3-methoxy-2-(1-methylethyl)-

PSORALEN

Fructus Psoraleae extract

Psoralen, >=99%

TGRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRY MJJNNNNNNN

Psoralea corylifolia Linn. Extract

furo(2’,3’,7,6)coumarin

furo(2’,3’:7’,6)coumarin

Furo(4',5',6,7)coumarin

furo(4’,5’,6,7)coumarin

furo(4’,5’:6,7)coumarin

Furo[2',3':7,6]coumarin

Furo[2'.3':7.6]coumarin

Furo[2’,3’:7,6]coumarin

furo[3,2-g]chromen-2-one

Furo[3,2-g]chromen-7-one

Psoralen, froM Psoralea corylifolia L.

Psoralen, 99%, from Psoralea corylifolia L.

PSORALEN, FOR FLUORESCENCE

6-Hydroxy-5-benzofuranacrylic acid γ-lactone

PSORALEN90%

PSORALEN(SH)

PSORALEN hplc

PSORALEN WITH HPLC

7H-Furo[3,2-γ],[1]benzopyran-7-one

Furo[3,2-γ],coumarin

7H-Furo[3,2-g]benzopyran-7-one, Furo[3,2-g]coumarin

7H-FURO[3,2-G][1]BENZOPYRAN-7-ONE

7h-furo[3,2-g]benzopyran-7-one

FURO[3,2-G]BENZOPYRAN-7-ONE

FURO[3,2-G]COUMARIN

FICUSIN

2-Propenoic acid, 3-(6-hydroxy-5-benzofuranyl)-, delta-lactone

2-Propenoicacid,3-(6-hydroxy-5-benzofuranyl)-,δ-lactone

3-(6-hydroxy-5-benzofuranyl)-2-propenoicacidelta-lactone

5-Benzofuranacrylic acid, 6-hydroxy-, delta-lactone

6,7-Furanocoumarin

6-hydroxy-5-benzofuranacrylicacidbeta-lactone

6-hydroxy-5-benzofuranacrylicacidelta-lactone

7H-Furo[3,2-g]chromen-7-one

Furo(2',3',7,6)coumarin

Furo[4',5':6,7]coumarin

Furo[4’,5’:6,7]coumarin

Furocoumarin

Psoralene

Psorline-P

Psoralen,7H-Furo[3,2-g]benzopyran-7-one, Furo[3,2-g]coumarin

Psoralen (Ficusin)

3-(6-Hydroxy-5-benzofuranyl)-2-propenoic Acid δ-Lactone

NSC 404562

Prosuler

Psoralea extract

7-furo[3,2-g][1]benzopyranone

Extract psoralen extract

in stock Psoralen 66-97-7

PSORALEAE FRUCTUS

Psoralen&gt

Psoralen USP/EP/BP

Psoralen (psoralene, Ficusin, Furocoumarin)