Forchlorfenuron Property

Melting point:

170-172°C

Boiling point:

308.4±27.0 °C(Predicted)

Density 

1.415±0.06 g/cm3(Predicted)

storage temp. 

Inert atmosphere,2-8°C

solubility 

Soluble in DMSO or Ethanol

pka

12.55±0.70(Predicted)

form 

Solid

color 

White or off-white

Stability:

Stable for 1 year from date ofpurchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

InChI

InChI=1S/C12H10ClN3O/c13-11-8-10(6-7-14-11)16-12(17)15-9-4-2-1-3-5-9/h1-8H,(H2,14,15,16,17)

InChIKey

GPXLRLUVLMHHIK-UHFFFAOYSA-N

SMILES

N(C1C=CN=C(Cl)C=1)C(NC1=CC=CC=C1)=O

CAS DataBase Reference

68157-60-8(CAS DataBase Reference)

EPA Substance Registry System

Forchlorfenuron (68157-60-8)

Safety

Hazard Codes 

Xi,N,Xn

Risk Statements 

36/37-51/53-40

Safety Statements 

26-36-61-46-36/37

RIDADR 

UN3077 9/PG 3

WGK Germany 

3

RTECS 

YS7182500

HazardClass 

9

PackingGroup 

III

HS Code 

29333990

Hazardous Substances Data

68157-60-8(Hazardous Substances Data)

Toxicity

LD50 oral in mouse: > 500mg/kg

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H351Suspected of causing cancer

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P391Collect spillage. Hazardous to the aquatic environment

P405Store locked up.

Forchlorfenuron Chemical Properties,Usage,Production

Description

Forchlorfenuron (68157-60-8) reversibly perturbs mammalian septin assembly, organization and function.? Has no effect on actin or tubulin polymerization.1,2 FCF induces effects on mitosis and migration which phenocopy the effects induced by septin depletion using siRNA.1 A useful tool for exploring the physiological role of septin and its complexes.3,4

Chemical Properties

White Solid

Chemical Properties

White to faint yellow crystalline powder.

Uses

Forchlorfenuronis is a diphenylurea-derivative cytokinin. Forchlorfenuronis is used as a plant growth regulator (PGR). Forchlorfenuronis is commonly used in horticulture to stimulate the growth of kiw i fruit and grapes.

Definition

ChEBI: Forchlorfenuron is a member of the class of phenylureas that is urea substituted by a phenyl group and a 2-chloropyridin-4-yl group at positions 1 and 3 respectively. It is a plant growth regulator widely used in agriculture for improving fruit quality and fruit size. It has a role as a plant growth regulator. It is a member of phenylureas and a monochloropyridine.

Agricultural Uses

Plant growth regulator: Forchlorfenuron is as a plant growth regulator to promote cell division, and to improve the quality and the yield of fruits, especially table grapes, grape raisins, and kiwi fruit. In some parts of California, forchlorfenuron is said to double the size of Thompson seedless grapes and delay crop maturity up to several weeks. widely used in agriculture on fruits to increase their size,

Trade name

CN-11-3183; KT-30®; SKW 20010

Potential Exposure

Phenylurea/substituted urea plant growth regulator widely used in agriculture on fruits to increase their size, to promote cell division, and to improve the quality and the yield of fruits, especially table grapes, grape raisins, and kiwi fruit. In some parts of California, forchlorfenuron is reputed to double the size of Thompson seedless grapes and delay crop maturity up to several weeks.

Shipping

UN2767 Phenyl urea pesticides, solid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.

Incompatibilities

May react with strong oxidizers such as chlorates, peroxides, nitrates, etc. Dust may form explosive mixture with air.

Waste Disposal

Containers must be disposed of properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office. If this material cannot be disposed of according to label instruc tions, it may be dissolved or mixed with a combustible sol vent and burned in a chemical incinerator equipped with an afterburner and scrubber. In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers.

References

1) Hu et al. (2008), Forchlorfenuron alters mammalian septin assembly, organization, and dynamics; J. Biol. Chem., 283 29563 2) DeMay et al. (2010), Cellular requirements for the small molecule forchlorfenuron to stabilize the septin cytoskeleton; Cytoskeleton, 67 383 3) Wasik et al. (2012), Septin 7 forms a complex with CD2AP and nephrin and regulates glucose transporter trafficking; Mol. Biol. Cell, 23 3370 4) Vardi-Oknin et al. (2013), Forchlorfenuron disrupts SEPT9_i1 filaments and inhibits HIF-1; PLoS One, 8(8) e73179