2,5-Dichloro-3-nitropyridine
- Product Name
- 2,5-Dichloro-3-nitropyridine
- CAS No.
- 21427-62-3
- Chemical Name
- 2,5-Dichloro-3-nitropyridine
- Synonyms
- 2,5-DICHLORO-3-NITROPYRIDINE;Pyridine, 2,5-dichloro-3-nitro-;2,5-Dichloro-3-nitropyridine>2,5-Dichloro-3-nitropyridine 97%;2,5-Dichloro-3-nitropyridine ,97%;2,5-Dichloro-3-nitropyridine ISO 9001：2015 REACH
- CBNumber
- CB3366215
- Molecular Formula
- C5H2Cl2N2O2
- Formula Weight
- 192.99
- MOL File
- 21427-62-3.mol
2,5-Dichloro-3-nitropyridine Property
- Melting point:
- 41-45 °C
- Boiling point:
- 265.3±35.0 °C(Predicted)
- Density
- 1.629±0.06 g/cm3(Predicted)
- Flash point:
- >110°(230°F)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- soluble in Methanol
- pka
- -4.99±0.10(Predicted)
- form
- Crystalline Powder and/or Chunks
- color
- Light beige-green to orange
- CAS DataBase Reference
- 21427-62-3(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn,Xi,T
- Risk Statements
- 36/37/38-22-43-41-37/38-25
- Safety Statements
- 36/37/39-26-45
- RIDADR
- 2811
- WGK Germany
- 1
- Hazard Note
- Harmful
- HazardClass
- 6.1
- PackingGroup
- Ⅲ
- HS Code
- 29333990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
N-Bromosuccinimide Price
- Product number
- 730548
- Product name
- 2,5-Dichloro-3-nitropyridine
- Purity
- 97%
- Packaging
- 5g
- Price
- $58.2
- Updated
- 2023/06/20
- Product number
- D4267
- Product name
- 2,5-Dichloro-3-nitropyridine
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $63
- Updated
- 2025/07/31
- Product number
- D4267
- Product name
- 2,5-Dichloro-3-nitropyridine
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $236
- Updated
- 2025/07/31
- Product number
- D438820
- Product name
- 2,5-Dichloro-3-nitropyridine
- Packaging
- 500mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- J52267
- Product name
- 2,5-Dichloro-3-nitropyridine
- Packaging
- 1g
- Price
- $10
- Updated
- 2021/12/16
2,5-Dichloro-3-nitropyridine Chemical Properties,Usage,Production
Chemical Properties
Light yellow crystalline powder
Uses
2,5-Dichloro-3-Nitropyridine has useful herbicidal properties. Furthermore, it is useful as a chemical intermediate for dyes, pharmaceutical and other agricultural applications.
Synthesis
5409-39-2
21427-62-3
(Step 1) 5-Chloro-3-nitropyridin-2-amine (10.0 g, 57.6 mmol) was dissolved in concentrated hydrochloric acid (100 mL), cooled to -10 °C and stirred continuously. An aqueous solution of sodium nitrite (9.94 g, 144 mmol) was slowly added dropwise (20 mL) over 30 min. After the dropwise addition, the reaction mixture was kept at 0 °C with continued stirring for 1 hour. Subsequently, the pH of the reaction solution was adjusted to 9 with 1N aqueous sodium hydroxide solution and then extracted with ethyl acetate. Insoluble impurities were removed by filtration and the organic layer was washed with saturated brine and dried with anhydrous magnesium sulfate. After filtration, the solvent was removed by distillation under reduced pressure to afford the target product 2,5-dichloro-3-nitropyridine (6.50 g, yield: 58.5%) as a solid.1H-NMR (CDCl3) δ: 8.60 (1H, d, J = 2.9 Hz), 8.24 (1H, d, J = 2.6 Hz).
References
[1] Patent: WO2007/67875, 2007, A2. Location in patent: Page/Page column 15
[2] Patent: JP2016/56134, 2016, A. Location in patent: Paragraph 0165; 0166; 0167
[3] Patent: JP2016/56133, 2016, A. Location in patent: Paragraph 0158; 0159
[4] Patent: EP3109239, 2016, A1. Location in patent: Paragraph 0189
[5] Journal of the Chemical Society, 1952, p. 2042,2044
2,5-Dichloro-3-nitropyridine Preparation Products And Raw materials
Raw materials
Preparation Products
2,5-Dichloro-3-nitropyridine Suppliers
- Tel
- --
- Fax
- --
- brunschwig@brunschwig.nl
- Country
- The Netherlands
- ProdList
- 4996
- Advantage
- 67
View Lastest Price from 2,5-Dichloro-3-nitropyridine manufacturers
- Product
- 2,5-Dichloro-3-nitropyridine 21427-62-3
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-05-30
- Product
- 2,5-Dichloro-3-nitropyridine 21427-62-3
- Price
- US $30.00-10.00/kg
- Min. Order
- 10kg
- Purity
- 99%
- Supply Ability
- 100000kg
- Release date
- 2024-08-22
- Product
- 2,5-Dichloro-3-nitropyridine 21427-62-3
- Price
- US $200.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%, 99.5% Sublimated
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-30