psoralidin
- Product Name
- psoralidin
- CAS No.
- 18642-23-4
- Chemical Name
- psoralidin
- Synonyms
- Psorslidin;psoralidin;Psoralidin-RM;Psoralidin, BR;Psoralidin (6CI);Psoralidin, >=99%;Psoralidin, 10 mM in DMSO;3,9-Dihydroxy-2-prenylcoumestan;3,9-dihydroxy-2-(3-methylbut-2-enyl)-[1]benzofuro[3,2-c]chromen-6-one;3,9-Dihydroxy-2-(3-methylbut-2-en-1-yl)-6H-benzofuro[3,2-c]chromen-6-one
- CBNumber
- CB41384552
- Molecular Formula
- C20H16O5
- Formula Weight
- 336.34
- MOL File
- 18642-23-4.mol
psoralidin Property
- Melting point:
- 290-292°
- Boiling point:
- 458.8±34.0 °C(Predicted)
- Density
- 1.383±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- solubility
- DMSO: soluble5mg/mL, clear (warmed)
- form
- powder
- pka
- 8.70±0.20(Predicted)
- color
- white to beige
- InChIKey
- YABIJLLNNFURIJ-UHFFFAOYSA-N
Safety
- WGK Germany
- 3
- HS Code
- 2932.20.4500
N-Bromosuccinimide Price
- Product number
- SML0932
- Product name
- Psoralidin
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $45.36
- Updated
- 2025/07/31
- Product number
- SML0932
- Product name
- Psoralidin
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $213
- Updated
- 2025/07/31
- Product number
- PHL82636
- Product name
- Psoralidin
- Purity
- phyproof? Reference Substance
- Packaging
- 10MG
- Price
- $416
- Updated
- 2025/07/31
- Product number
- P2605
- Product name
- Psoralidin
- Purity
- >98.0%(HPLC)
- Packaging
- 25mg
- Price
- $230
- Updated
- 2025/07/31
- Product number
- P2605
- Product name
- Psoralidin
- Purity
- >98.0%(HPLC)
- Packaging
- 100mg
- Price
- $688
- Updated
- 2025/07/31
psoralidin Chemical Properties,Usage,Production
Description
Psoralidin is a furanocoumarin isolated from the seeds of P. corylifolia, a medicinal plant found in southeastern Asia, that has been shown to induce cytotoxicity against various cancer cells. Through TNF-
Chemical Properties
Pale yellow crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO. It is derived from the seeds of Psoralea corylifolia Linn.
Uses
Psoralidin is an antibacterial and antioxidant reagent.
Definition
ChEBI: A member of the class of coumestans that is coumestan substituted by hydroxy groups at positions 3 and 9 and a prenyl group at position 2 respectively.
in vivo
Psoralidin (5 mg/kg) regulates expression of pro-inflammatory cytokines that play an important role in inflammatory diseasesin IR-irradiated lung of BALB/c mouse[1].
| Animal Model: | BALB/c mice[1] |
| Dosage: | 5 mg/kg |
| Administration: | Intraperitoneal application; 30 min before and 1 h after IR irradiation (20 Gy). |
| Result: | Anti-inflammatory effect in IR-irradiated mice. |
IC 50
COX-2; 5-LOX
References
[1] yang h j, youn h s, seong k m, et al. psoralidin, a dual inhibitor of cox-2 and 5-lox, regulates ionizing radiation (ir)-induced pulmonary inflammation[j]. biochemical pharmacology, 2011, 82(5): 524-534.
[2] chiou w f, don m j, liao j f, et al. psoralidin inhibits lps-induced inos expression via repressing syk-mediated activation of pi3k-ikk-iκb signaling pathways[j]. european journal of pharmacology, 2011, 650(1): 102-109.
[3] bronikowska j, szliszka e, jaworska d, et al. the coumarin psoralidin enhances anticancer effect of tumor necrosis factor-related apoptosis-inducing ligand (trail)[j]. molecules, 2012, 17(6): 6449-6464.
psoralidin Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from psoralidin manufacturers
- Product
- psoralidin 18642-23-4
- Price
- US $0.00-0.00/KG
- Min. Order
- 5mg
- Purity
- 99%HPLC
- Supply Ability
- 2000tons
- Release date
- 2020-01-06
- Product
- Psoralidin 18642-23-4
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2019-10-29
- Product
- psoralidin 18642-23-4
- Price
- US $1.00/kg
- Min. Order
- 1 mg
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2018-12-25