ChemicalBook > CAS DataBase List > psoralidin

psoralidin

Product Name
psoralidin
CAS No.
18642-23-4
Chemical Name
psoralidin
Synonyms
Psorslidin;psoralidin;Psoralidin-RM;Psoralidin, BR;Psoralidin (6CI);Psoralidin, >=99%;3,9-Dihydroxy-2-prenylcoumestan;3,9-dihydroxy-2-(3-methylbut-2-enyl)-[1]benzofuro[3,2-c]chromen-6-one;3,9-Dihydroxy-2-(3-methylbut-2-en-1-yl)-6H-benzofuro[3,2-c]chromen-6-one;3,9-Dihydroxy-2-(3-methyl-2-butenyl)-6H-benzofuro[3,2-c][1]benzopyran-6-one
CBNumber
CB41384552
Molecular Formula
C20H16O5
Formula Weight
336.34
MOL File
18642-23-4.mol
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psoralidin Property

Melting point:
290-292°
Boiling point:
458.8±34.0 °C(Predicted)
Density 
1.383±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility 
DMSO: soluble5mg/mL, clear (warmed)
form 
powder
pka
8.70±0.20(Predicted)
color 
white to beige
InChIKey
YABIJLLNNFURIJ-UHFFFAOYSA-N
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Safety

WGK Germany 
3
HS Code 
2932.20.4500
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0932
Product name
Psoralidin
Purity
≥98% (HPLC)
Packaging
5mg
Price
$74.1
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0932
Product name
Psoralidin
Purity
≥98% (HPLC)
Packaging
25mg
Price
$286
Updated
2024/03/01
Sigma-Aldrich
Product number
PHL82636
Product name
Psoralidin
Purity
phyproof? Reference Substance
Packaging
10MG
Price
$446
Updated
2024/03/01
TCI Chemical
Product number
P2605
Product name
Psoralidin
Purity
>98.0%(HPLC)
Packaging
25mg
Price
$255
Updated
2024/03/01
TCI Chemical
Product number
P2605
Product name
Psoralidin
Purity
>98.0%(HPLC)
Packaging
100mg
Price
$764
Updated
2024/03/01
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psoralidin Chemical Properties,Usage,Production

Description

Psoralidin is a furanocoumarin isolated from the seeds of P. corylifolia, a medicinal plant found in southeastern Asia, that has been shown to induce cytotoxicity against various cancer cells. Through TNF-related apoptosis-inducing ligand-mediated events, psoralidin at 50 μM can induce the death of HeLa cancer cells. It also can induce apoptosis of androgen-dependent (LNCaP, C4-2B) and androgen-independent (DU-145, PC-3) prostate cancer cells and inhibit the growth of PC-3 xenograft tumors in nude mice.

Uses

Psoralidin is an antibacterial and antioxidant reagent.

Definition

ChEBI: A member of the class of coumestans that is coumestan substituted by hydroxy groups at positions 3 and 9 and a prenyl group at position 2 respectively.

References

[1] yang h j, youn h s, seong k m, et al. psoralidin, a dual inhibitor of cox-2 and 5-lox, regulates ionizing radiation (ir)-induced pulmonary inflammation[j]. biochemical pharmacology, 2011, 82(5): 524-534.
[2] chiou w f, don m j, liao j f, et al. psoralidin inhibits lps-induced inos expression via repressing syk-mediated activation of pi3k-ikk-iκb signaling pathways[j]. european journal of pharmacology, 2011, 650(1): 102-109.
[3] bronikowska j, szliszka e, jaworska d, et al. the coumarin psoralidin enhances anticancer effect of tumor necrosis factor-related apoptosis-inducing ligand (trail)[j]. molecules, 2012, 17(6): 6449-6464.

psoralidin Preparation Products And Raw materials

Raw materials

Preparation Products

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psoralidin Suppliers

China 177 Germany 1 India 1 Japan 1 Switzerland 1 United States 17 USA 1 Global 199
Chembest Research Laboratories Limited
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View Lastest Price from psoralidin manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
psoralidin 18642-23-4
Price
US $0.00-0.00/KG
Min. Order
5mg
Purity
99%HPLC
Supply Ability
2000tons
Release date
2020-01-06
Shanghai Standard Technology Co., Ltd.
Product
Psoralidin 18642-23-4
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2019-10-29
Career Henan Chemical Co
Product
psoralidin 18642-23-4
Price
US $1.00/kg
Min. Order
1 mg
Purity
99%
Supply Ability
100KG
Release date
2018-12-25

18642-23-4, psoralidinRelated Search:

Hederagenin Naringin MERANZIN AURANTIO-OBTUSIN 6-Hydroxypurine Emodin-3-methyl ether Psoralen HINOKIFLAVONE L-Theanine Formononetin Toosendanin TYROSINASE 7,8-Dihydroxycoumarin Gallic acid monohydrate epiberberine psoralidin COUMESTROL neoglycyrol

  • 3,9-Dihydroxy-2-prenylcoumestan
  • Psoralidin, >=99%
  • psoralidin
  • 3,9-Dihydroxy-2-(3-methyl-2-butenyl)-6H-benzofuro[3,2-c][1]benzopyran-6-one
  • Psorslidin
  • Psoralidin, BR
  • 6H-Benzofuro[3,2-c][1]benzopyran-6-one, 3,9-dihydroxy-2-(3-methyl-2-buten-1-yl)-
  • 3,9-Dihydroxy-2-(3-methylbut-2-en-1-yl)-6H-benzofuro[3,2-c]chromen-6-one
  • 3,9-dihydroxy-2-(3-methylbut-2-enyl)-[1]benzofuro[3,2-c]chromen-6-one
  • Psoralidin (6CI)
  • Psoralidin-RM
  • 18642-23-4