ChemicalBook > CAS DataBase List > 7-Fluoroindole

7-Fluoroindole

Product Name
7-Fluoroindole
CAS No.
387-44-0
Chemical Name
7-Fluoroindole
Synonyms
7-FLUORO-1H-INDOLE;uoro-1H-indoL;7-ETHOXYINDOLE;7-FLUOROINDOLE;7-Flouroindole;7-Fluoroindole>BUTTPARK 24\07-35;7-Fluoroindole,97%;7-Fluoroindole,98%;1H-Indole, 7-fluoro-
CBNumber
CB4168733
Molecular Formula
C8H6FN
Formula Weight
135.14
MOL File
387-44-0.mol
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7-Fluoroindole Property

Melting point:
61 °C
Boiling point:
258.0±13.0 °C(Predicted)
Density 
1.273±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Soluble in methanol. (almost transparency)
pka
15.55±0.30(Predicted)
form 
powder to crystal
color 
White to Light yellow to Light orange
BRN 
114740
InChIKey
XONKJZDHGCMRRF-UHFFFAOYSA-N
CAS DataBase Reference
387-44-0(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-41-37/38-22
Safety Statements 
26-36-39
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
740764
Product name
7-Fluoro-1H-indole
Purity
97%
Packaging
5g
Price
$207
Updated
2024/03/01
TCI Chemical
Product number
F0555
Product name
7-Fluoroindole
Purity
>98.0%(GC)
Packaging
1g
Price
$122
Updated
2024/03/01
Alfa Aesar
Product number
L17621
Product name
7-Fluoroindole, 97%
Packaging
250mg
Price
$54.65
Updated
2024/03/01
Alfa Aesar
Product number
L17621
Product name
7-Fluoroindole, 97%
Packaging
1g
Price
$117.65
Updated
2024/03/01
TRC
Product number
F592268
Product name
7-Fluoroindole
Packaging
2.5g
Price
$140
Updated
2021/12/16
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7-Fluoroindole Chemical Properties,Usage,Production

Chemical Properties

Brown solid

Uses

7-Fluoroindole is a reagent used in chemical synthesis. It has been used to synthesize antiviral compounds against Pseudomonas aeruginosa and Staphylococcus aureus along with creation of immunomodulators. It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuffs.

Antimicrobial activity

7-fluoroindole (7FI) was identified as a compound that inhibits biofilm formation and blood hemolysis without inhibiting the growth of planktonic P. aeruginosa cells. Moreover, 7FI markedly reduced the production of quorum-sensing (QS)-regulated virulence factors 2-heptyl-3-hydroxy-4(1H)-quinolone, pyocyanin, rhamnolipid, two siderophores, pyoverdine and pyochelin. 7FI clearly suppressed swarming motility, protease activity and the production of a polymeric matrix in P. aeruginosa. However, unlike natural indole compounds, synthetic 7FI did not increase antibiotic resistance. Therefore, 7FI is a potential candidate for use in an antivirulence approach against persistent P. aeruginosa infection.

7-Fluoroindole Preparation Products And Raw materials

Raw materials

Vinylmagnesium bromide Tetrahydrofuran 1-Fluoro-2-nitrobenzene

Preparation Products

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7-Fluoroindole Suppliers

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View Lastest Price from 7-Fluoroindole manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
7-Fluoroindole 387-44-0
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20t
Release date
2024-06-25
Shaanxi Dideu Medichem Co. Ltd
Product
7-Fluoroindole 387-44-0
Price
US $0.10/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
1000 tons
Release date
2020-04-24
Henan Fengda Chemical Co., Ltd
Product
7-Fluoroindole 387-44-0
Price
US $36.00-1.50/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-09

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