H2N-PEG6-tBu
- Product Name
- H2N-PEG6-tBu
- CAS No.
- 1286281-32-0
- Chemical Name
- H2N-PEG6-tBu
- Synonyms
- tert-Butyl 1-amino-3,6,9,12,15,18-hexaoxahenicosan-21-oate;H2N-PEG6-CH2CH2COOtBu;NH2-PEG6-Boc;H2N-PEG6-tBu;Amino-PEG6-COOtBu;NH2-PEG7-CH2COOtBu;NH2-PEG6-C2-COOtBu;NH2-PEG6-CH2CH2COOtBu;Amino-PEG6-t-Bu Ester;Amino-PEG7-t-butyl ester
- CBNumber
- CB42546870
- Molecular Formula
- C19H39NO8
- Formula Weight
- 409.51
- MOL File
- 1286281-32-0.mol
H2N-PEG6-tBu Property
- Boiling point:
- 475.9±40.0 °C(Predicted)
- Density
- 1.056±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- form
- Oil
- pka
- 8.74±0.10(Predicted)
- color
- Colorless to light yellow
Safety
- HS Code
- 2942000090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 902659
- Product name
- Amino-PEG6-t-butyl ester
- Packaging
- 250MG
- Price
- $195
- Updated
- 2023/06/20
- Product number
- 902659
- Product name
- Amino-PEG6-t-butyl ester
- Packaging
- 1G
- Price
- $714
- Updated
- 2023/06/20
- Product number
- A615298
- Product name
- Amino-PEG6-t-butylEster
- Packaging
- 100mg
- Price
- $110
- Updated
- 2021/12/16
- Product number
- 10061
- Product name
- Amino-dPEG®₆-t-butylester
- Packaging
- 100mg
- Price
- $135
- Updated
- 2021/12/16
- Product number
- 280404
- Product name
- H2N-PEG6-tBu
- Packaging
- 1g
- Price
- $270
- Updated
- 2021/12/16
H2N-PEG6-tBu Chemical Properties,Usage,Production
Description
Amino-PEG6-t-butyl ester is a PEG reagent containing an amino NH2 group with a t-butyl protected carboxyl group (Boc). The hydrophilic PEG spacer increases solubility in aqueous media. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
Uses
This heterobifunctional, PEGylated crosslinker features an amino group at one end and t-butyl-protected carboxyl group at the other, which can be deprotected with acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. Amino-PEG6-t-butyl ester can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.
H2N-PEG6-tBu Preparation Products And Raw materials
Raw materials
Preparation Products
H2N-PEG6-tBu Suppliers
- Tel
- --
- Fax
- --
- sales@apolloscientific.co.uk
- Country
- United Kingdom
- ProdList
- 6084
- Advantage
- 88
View Lastest Price from H2N-PEG6-tBu manufacturers
- Product
- Amino-PEG6-COOtBu 1286281-32-0
- Price
- US $0.00/mg
- Min. Order
- 250mg
- Purity
- >98.00%
- Supply Ability
- 250mg
- Release date
- 2024-03-22