Synthesis
ChemicalBook > CAS DataBase List > Ethyl 1-benzylpiperidine-4-carboxylate

Ethyl 1-benzylpiperidine-4-carboxylate

Synthesis
Product Name
Ethyl 1-benzylpiperidine-4-carboxylate
CAS No.
24228-40-8
Chemical Name
Ethyl 1-benzylpiperidine-4-carboxylate
Synonyms
AKOS 225-01;BUTTPARK 33\04-91;RSYY(Avanafil)-28;RARECHEM AH CK 0037;SDCCGMLS-0066147.P001;Ethyl 1-Benzylisonipecotate;Ethyl N-benzylisonipecotate;1-benzyl-ethyl Isonipecotate;Ethyl N-benzylisonipecotinate;1-Benzyl-4-piperidinecarboxyli
CBNumber
CB4276544
Molecular Formula
C15H21NO2
Formula Weight
247.33
MOL File
24228-40-8.mol
More
Less

Ethyl 1-benzylpiperidine-4-carboxylate Property

Boiling point:
122°C (0.5 mmHg)
Density 
1.037 g/mL at 25 °C
refractive index 
1.5120-1.5160
Flash point:
>110℃
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Chloroform (Slightly), Hexanes (Slightly), Methanol (Slightly)
form 
clear liquid
pka
7.93±0.10(Predicted)
color 
Colorless to Light red
CAS DataBase Reference
24228-40-8(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi,T
Risk Statements 
36/37/38-25
Safety Statements 
24/25-45
RIDADR 
UN 2810 6.1 / PGIII
Hazard Note 
Irritant
HS Code 
29333990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
E0862
Product name
Ethyl 1-Benzyl-4-piperidinecarboxylate
Purity
>95.0%(GC)(T)
Packaging
5g
Price
$57
Updated
2023/06/20
TCI Chemical
Product number
E0862
Product name
Ethyl 1-Benzyl-4-piperidinecarboxylate
Purity
>95.0%(GC)(T)
Packaging
25g
Price
$203
Updated
2021/12/16
Alfa Aesar
Product number
H52374
Product name
Ethyl 1-benzylpiperidine-4-carboxylate, 97+%
Packaging
5g
Price
$87.7
Updated
2021/12/16
Alfa Aesar
Product number
H52374
Product name
Ethyl 1-benzylpiperidine-4-carboxylate, 97+%
Packaging
1g
Price
$26.5
Updated
2021/12/16
Alfa Aesar
Product number
H52374
Product name
Ethyl 1-benzylpiperidine-4-carboxylate, 97+%
Packaging
250mg
Price
$9.6
Updated
2021/12/16
More
Less

Ethyl 1-benzylpiperidine-4-carboxylate Chemical Properties,Usage,Production

Synthesis

Ethyl isonipecotate (50 g, 0.31 mol) was dissolved in toluene (150 mL) in a round bottom flask, charged with potassium carbonate (60 g, 0.43 mol) and stirred for 15 min. Benzyl chloride (42 g, 0.31 mol) was charged and the reaction mass was refluxed for 4 h at 100 °C. Upon completion of the reaction as marked by TLC (hexane:ethyl acetate; 2:1), the reaction mass was cooled to room temperature and quenched with water (100 mL), stirred and the organic phase was separated. The aqueous phase was again extracted with toluene (100 mL). Combined organic phase was washed twice with saturated brine solution (50 mL). Remove toluene in vacuo to obtain Ethyl N-benzylpiperidine-4-carboxylate ( 6.97 g, 91 %) as a yellow liquid.

Chemical Properties

Colourless Oil

Ethyl 1-benzylpiperidine-4-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Ethyl 1-benzylpiperidine-4-carboxylate Suppliers

Anhui Dexinjia Biopharm Co., Ltd
Tel
0531-82375878 15269101859
Email
2710825968@qq.com
Country
China
ProdList
304
Advantage
58
Shanghai Hobor Chemical Co., Ltd
Tel
21-21-61026752 13918007836
Fax
021-51685238
Email
sales@hoborchem.com
Country
China
ProdList
350
Advantage
60
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1995
Advantage
65
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
Tel
0311-89250318 031166536426
Fax
4000311741
Email
master@sjzsdyn.com
Country
China
ProdList
2963
Advantage
65
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
More
Less

View Lastest Price from Ethyl 1-benzylpiperidine-4-carboxylate manufacturers

Hebei Kingfiner Technology Development Co.Ltd
Product
Ethyl N-benzylpiperidine-4-carboxylate 24228-40-8
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
50000kg
Release date
2023-12-12
Wuhan Xinhao Biotechnology Co., Ltd
Product
Ethyl 1-benzylpiperidine-4-carboxylate 24228-40-8
Price
US $10.00-100.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000 Metric Ton/Month
Release date
2024-03-20
Hebei Fengqiang Trading Co., LTD
Product
Ethyl N-benzyl piperidine-4-carboxylate 24228-40-8
Price
US $100.00/bag
Min. Order
1bag
Purity
99
Supply Ability
5000
Release date
2023-09-11

24228-40-8, Ethyl 1-benzylpiperidine-4-carboxylateRelated Search:


  • RARECHEM AH CK 0037
  • AKOS 225-01
  • 1-BENZYLPIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER
  • ETHYL 1-BENZYL-4-PIPERIDINECARBOXYLATE
  • ETHYL 1-BENZYLPIPERIDINE-4-CARBOXYLATE
  • BUTTPARK 33\04-91
  • 1-(Phenylmethyl)-4-piperidinecarboxylic Acid Ethyl Ester
  • 1-(Phenylmethyl)piperidine-4-carboxylic Acid Ethyl Ester
  • Ethyl 1-Benzylisonipecotate
  • Ethyl 1-Benzylpiperidine-4-carboxylat
  • N-Benzyl-4-carboethoxypiperidine
  • 1-Benzyl-4-piperidinecarboxyli
  • N-Benzyl-4-piperidinecarboxylicacidethylester
  • Methyl(ethyl) 1-benzyl-Piperidine-4-carboxylate
  • 1-BENZYL-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER >98%
  • Benzylpiperidinecarboxylicacidethylester
  • N-Benzyl-4-cabethoxypiperidine
  • Ethyl 1-benzylpiperidine-4-carboxylate, 97+%
  • 4-Piperidinecarboxylic acid, 1-(phenylMethyl)-, ethyl ester
  • N-Ethyl N-benzylpiperidine-4-carboxylate
  • Ethyl N-benzylpiperidine-4-carboxylate
  • Ethyl-benzylpiperidine-4-carboxylate
  • 1-Benzyl-4-piperidinecarboxylic Acid Ethyl Ester Ethyl 1-Benzylisonipecotate 1-Benzylisonipecotic Acid Ethyl Ester
  • Ethyl 1-benzylisonipecotate, 1-Benzyl-4-(ethoxycarbonyl)piperidine
  • N-benzyl -4-piperidine forMic acid ethyl ester
  • 1 - benzyl - 4 - piperidine ethyl forMate
  • Ethyl N-benzyl-4-piperidinecarboxylate
  • CAS NO.24228-40-8 Ethyl N-benzylpiperidine-4-carboxylate
  • SDCCGMLS-0066147.P001
  • Ethyl1-Benzyl-4-piperidinecarboxylate&gt
  • Ethyl N-benzylisonipecotinate
  • N-benzyl isonipecotic ethyl ester
  • N-benzylpiperidine-4-carboxylate, ethyl ester
  • 1-Benzylisonipecotic Acid Ethyl Ester
  • 1-benzyl-ethyl Isonipecotate
  • 1-Benzyl-piperidine-4-carboxylic a
  • RSYY(Avanafil)-28
  • Ethyl N-benzylisonipecotate
  • 24228-40-8
  • 24228-04-8
  • 12001-70-3
  • C24H29NO3HCl
  • Piperidine
  • Heterocyclic Compounds
  • Aromatics
  • Heterocycles