ChemicalBook > CAS DataBase List > propargyl-PEG3-Acid

propargyl-PEG3-Acid

Product Name
propargyl-PEG3-Acid
CAS No.
1347760-82-0
Chemical Name
propargyl-PEG3-Acid
Synonyms
Alkyne-PEG3-COOH;Alkyne-PEG3-acid;propargyl-PEG3-Acid;Propargyl-PEG2-COOH;PROPARGYL-PEG3-COOH;Propargyl-PEG2-C2-COOH;Propyne-PEG2-CH2CH2COOH;Propargyl-PEG2-CH2CH2COOH;Propargyl-PEG4-(CH2)3-acid;Propargyl-PEG3-Carboxylic Acid
CBNumber
CB43048728
Molecular Formula
C10H16O5
Formula Weight
216.23
MOL File
1347760-82-0.mol
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propargyl-PEG3-Acid Property

storage temp. 
-20°C
solubility 
Soluble in Water, DMSO, DCM, DMF
form 
clear liquid
color 
Light yellow to Brown
Appearance
yellow oily liquid
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Safety

HS Code 
2918.99.5000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
901565
Product name
Propargyl-PEG3-acid
Packaging
50MG
Price
$144.44
Updated
2025/07/31
TCI Chemical
Product number
P2733
Product name
Propargyl-PEG3-Carboxylic Acid
Packaging
50MG
Price
$78
Updated
2025/07/31
TCI Chemical
Product number
P2733
Product name
Propargyl-PEG3-Carboxylic Acid
Packaging
250MG
Price
$238
Updated
2025/07/31
TRC
Product number
P839575
Product name
Propargyl-PEG3-Acid
Packaging
50mg
Price
$155
Updated
2021/12/16
TRC
Product number
P839575
Product name
Propargyl-PEG3-Acid
Packaging
100mg
Price
$220
Updated
2021/12/16
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propargyl-PEG3-Acid Chemical Properties,Usage,Production

Description

Propargyl-PEG3-acid is a reagent with an alkyne group and a carboxylic acid. The terminal carboxylic acid can form amide bond with primary amines (activation is needed). The alkyne can form triazole linkage with azide containing molecules via copper catalyzed reactions.

Uses

Propargyl-PEG3-acid is a heterobifunctional, PEGylated crosslinker featuring a carboxylic acid at one end and propargyl group at the other for reaction with azide-containing compounds using click chemistry. The hydrophillic PEG linker facilitates solubility in biological applications. Propargyl-PEG3-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.

reaction suitability

reagent type: linker

IC 50

PEGs; Non-cleavable Linker

propargyl-PEG3-Acid Preparation Products And Raw materials

Raw materials

Preparation Products

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propargyl-PEG3-Acid Suppliers

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View Lastest Price from propargyl-PEG3-Acid manufacturers

LAURENT
Product
Propargyl-PEG2-CH2CH2COOH 1347760-82-0
Price
US $27.00/g
Min. Order
1g
Purity
98%
Supply Ability
300kg
Release date
2025-11-22
Xian confluore Biological Technology Co., Ltd.
Product
Propargyl-PEG3-acid 1347760-82-0
Price
US $0.00/g
Min. Order
5g
Purity
>98.00%
Supply Ability
5g
Release date
2024-03-26

1347760-82-0, propargyl-PEG3-AcidRelated Search:

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  • Propanoic acid, 3-[2-[2-(2-propyn-1-yloxy)ethoxy]ethoxy]-
  • Propargyl-PEG3-Carboxylic Acid
  • 3-[2-[2-(2-Propargyloxy)ethoxy]ethoxy]propanoic Acid
  • 3-[2-(2-Prop-2-ynoxyethoxy)ethoxy]propanoic acid
  • Propargyl-PEG2-CH2CH2COOH/Propanoic acid, 3-[2-[2-(2-propyn-1-yloxy)ethoxy]ethoxy]-
  • Propargyl-PEG2-C2-COOH
  • Propargyl PEG3 acid,PROTAC Linkers,PropargylPEG3acid,Inhibitor,ADC Linkers,inhibit,Antibody-drug conjugates linkers,Propargyl-PEG-3-acid
  • Propargyl-PEG<sub>3</sub>-acid
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  • 1347760-82-0
  • peg