2-FLUORO-6-HYDROXYBENZALDEHYDE

Product Name: 2-FLUORO-6-HYDROXYBENZALDEHYDE
CAS No.: 38226-10-7
Chemical Name: 2-FLUORO-6-HYDROXYBENZALDEHYDE
Synonyms: 6-FLUOROSALICYLALDEHYDE;6-Fluorosalicylaldehyde>6-Fluorosalicylaldehyde,97%;4-Fluoro-4-nitroacetophneone;2-Fluor-6-Hydroxybenzaldehyde;2-FLUORO-6-HYDROXYBENZALDEHYDE;Benzaldehyde, 2-fluoro-6-hydroxy-;2-Fluoro-6-hydroxybenzaldehyde 98%;6-Fluorosalicylaldehyde, 3-Fluoro-2-formylphenol
CBNumber: CB4306380
Molecular Formula: C7H5FO2
Formula Weight: 140.11
MOL File: 38226-10-7.mol

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2-FLUORO-6-HYDROXYBENZALDEHYDE Property

Melting point:: 37-39°C
Boiling point:: 201.3±20.0 °C(Predicted)
Density: 1.350±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: powder to lump
pka: 7.18±0.10(Predicted)
color: White to Yellow to Orange
Sensitive: Air Sensitive
BRN: 1935289
InChI: InChI=1S/C7H5FO2/c8-6-2-1-3-7(10)5(6)4-9/h1-4,10H
InChIKey: FZIBGCDUHZBOLA-UHFFFAOYSA-N
SMILES: C(=O)C1=C(O)C=CC=C1F
CAS DataBase Reference: 38226-10-7(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-36/37/39-27
Hazard Note: Irritant
HS Code: 2912490090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical

Product number: F0988
Product name: 6-Fluorosalicylaldehyde
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $142
Updated: 2025/07/31

TCI Chemical

Product number: F0988
Product name: 6-Fluorosalicylaldehyde
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $503
Updated: 2025/07/31

TRC

Product number: F595905
Product name: 6-Fluorosalicylaldehyde
Packaging: 100mg
Price: $120
Updated: 2021/12/16

Usbiological

Product number: 012410
Product name: 6-Fluorosalicylaldehyde
Packaging: 100mg
Price: $403
Updated: 2021/12/16

AK Scientific

Product number: W5897
Product name: 2-Fluoro-6-hydroxybenzaldehyde
Packaging: 25g
Price: $295
Updated: 2021/12/16

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2-FLUORO-6-HYDROXYBENZALDEHYDE Chemical Properties,Usage,Production

Uses

2-FLUORO-6-HYDROXYBENZALDEHYDE is used in the preparation of aromatic compounds as human PAI-1 inhibitors.

Synthesis

199388-02-8

38226-10-7

Step 3: Synthesis of 2-fluoro-6-hydroxybenzaldehyde A solution of 2-fluoro-6-((tetrahydro-2H-pyran-2-yl)oxy)benzaldehyde (6.5 g, 29.0 mmol) and p-toluenesulfonic acid (TsOH, 2 g, 11.6 mmol) in dichloromethane (DCM, 30 mL) was stirred for 5 hours at room temperature. After completion of the reaction, the mixture was diluted with dichloromethane (100 mL). The organic layer was washed sequentially with saturated aqueous sodium bicarbonate and brine, dried over anhydrous sodium sulfate and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography (eluent: petroleum ether/ethyl acetate = 100:1 to 20:1 gradient elution) to afford 2-fluoro-6-hydroxybenzaldehyde (3.0 g, 74% yield) as a light yellow solid. 1H NMR (400 MHz, CDCl3): δ 11.49 (s, 1H), 10.29 (s, 1H), 7.46-7.52 (m, 1H), 6.79 (d, J = 8.8 Hz, 1H), 6.63-6.68 (m, 1H).

References

[1] Journal of the Chemical Society - Perkin Transactions 1, 1997, # 19, p. 2925 - 2929
[2] Patent: US2017/37038, 2017, A1. Location in patent: Paragraph 0096; 0378; 0382; 0383

2-FLUORO-6-HYDROXYBENZALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-FLUORO-6-HYDROXYBENZALDEHYDE Suppliers

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View Lastest Price from 2-FLUORO-6-HYDROXYBENZALDEHYDE manufacturers

Career Henan Chemical Co

Product: 2-FLUORO-6-HYDROXYBENZALDEHYDE 38226-10-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: 95%
Supply Ability: 500kg
Release date: 2018-08-19

38226-10-7, 2-FLUORO-6-HYDROXYBENZALDEHYDERelated Search:

2-FLUORO-6-HYDROXYBENZALDEHYDE 2'-FLUORO-6'-HYDROXYACETOPHENONE 2-FLUORO-6-PHENOXYBENZALDEHYDE 2,3-DIFLUORO-6-METHOXYBENZALDEHYDE 2-FLUORO-6-METHOXYBENZOIC ACID 2'-FLUORO-6'-METHOXYACETOPHENONE 2-Fluoro-6-methoxybenzaldehyde 2-Fluoro-6-hydroxybenzoic acid 3-FLUORO-4-HYDROXYBENZALDEHYDE 2-FLUORO-4-HYDROXYBENZALDEHYDE 3-FLUORO-2-HYDROXYBENZALDEHYDE,3-Fluoro-2-hydroxybenzaldehyde ,99%,3-Fluoro-2-Hydroxybenzaldehyde 3-Fluoro Salicylaldehyde 2-FLUORO-5-HYDROXYBENZALDEHYDE 5-Fluorosalicylaldehyde 4-FLUORO-2-HYDROXYBENZALDEHYDE,4-FLUOROSALICYLALDEHYDE (4-FLUORO-2-HYDROXYBENZALDEHYDE) METHYL 2-FLUORO-6-HYDROXYBENZOATE 2-FLUORO-6-METHOXYBENZAMIDE 3,4,5,6-TETRAFLUORO-2-HYDROXYBENZOIC ACID 5-BROMO-3-FLUORO-2-HYDROXYBENZALDEHYDE

2-FLUORO-6-HYDROXYBENZALDEHYDE

6-FLUOROSALICYLALDEHYDE

6-Fluorosalicylaldehyde,97%

2-Fluoro-6-hydroxybenzaldehyde 98%

6-Fluorosalicylaldehyde, 3-Fluoro-2-formylphenol

2-Fluor-6-Hydroxybenzaldehyde

6-Fluorosalicylaldehyde&gt

Benzaldehyde, 2-fluoro-6-hydroxy-

4-Fluoro-4-nitroacetophneone

38226-10-7

Aromatic Aldehydes & Derivatives (substituted)

Aromatics

Inhibitors