ChemicalBook > CAS DataBase List > 4-Chloro-5-iodo-7H-pyrrol[2,3-d]pyrimidine

4-Chloro-5-iodo-7H-pyrrol[2,3-d]pyrimidine

Product Name
4-Chloro-5-iodo-7H-pyrrol[2,3-d]pyrimidine
CAS No.
123148-78-7
Chemical Name
4-Chloro-5-iodo-7H-pyrrol[2,3-d]pyrimidine
Synonyms
4-Chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidine;EOS-62121;6-Chloro-7-iodo-deazapurine;4-Chloro-5-iodo-1H-pyrrol...;6-Chloro-7-iodo-7-deazapurine;6-Chloro-7-iodo-7-deazapurine,96%;6-Chloro-7-iodo-7-deazapurine >Name 6-Chloro-7-iodo-7-deazapurine;4-CHLORO-5-IODO-7H-PYRROL[2,3]PYRIMIDINE;4-Chloro-5-iodo-7H-pyrrol[2,3-d]pyrimidine
CBNumber
CB51075334
Molecular Formula
C6H3ClIN3
Formula Weight
279.47
MOL File
123148-78-7.mol
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4-Chloro-5-iodo-7H-pyrrol[2,3-d]pyrimidine Property

Melting point:
179-183 °C
Boiling point:
241.0±50.0 °C(Predicted)
Density 
2.47±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
powder to crystal
pka
9.61±0.20(Predicted)
color 
White to Orange to Green
Water Solubility 
Insoluble in water.
Sensitive 
Light Sensitive
λmax
305nm(H2O)(lit.)
InChI
InChI=1S/C6H3ClIN3/c7-5-4-3(8)1-9-6(4)11-2-10-5/h1-2H,(H,9,10,11)
InChIKey
CBWBJFJMNBPWAL-UHFFFAOYSA-N
SMILES
C1=NC(Cl)=C2C(I)=CNC2=N1
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38-R36/37/38-R22
Safety Statements 
26-36/37-S36/37-S26-37
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29335990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
699497
Product name
6-Chloro-7-iodo-7-deazapurine
Purity
95%
Packaging
1g
Price
$44.55
Updated
2025/07/31
TCI Chemical
Product number
C3130
Product name
6-Chloro-7-iodo-7-deazapurine
Purity
>95.0%(GC)(T)
Packaging
1g
Price
$30
Updated
2025/07/31
TCI Chemical
Product number
C3130
Product name
6-Chloro-7-iodo-7-deazapurine
Purity
>95.0%(GC)(T)
Packaging
5g
Price
$118
Updated
2025/07/31
TRC
Product number
C371260
Product name
4-Chloro-5-iodopyrrolo[2,3-d]pyrimidine
Packaging
25g
Price
$330
Updated
2021/12/16
TRC
Product number
C371260
Product name
4-Chloro-5-iodopyrrolo[2,3-d]pyrimidine
Packaging
50g
Price
$545
Updated
2021/12/16
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4-Chloro-5-iodo-7H-pyrrol[2,3-d]pyrimidine Chemical Properties,Usage,Production

Uses

6-Chloro-7-iodo-7-deazapurine is used as pharmaceutical intermediate.

Definition

4-Chloro-5-iodo-7H-pyrrol[2,3-d]pyrimidine, also known as 6-Chloro-7-iodo-7-deazapurine or 4-Chloro-5-iodo-1H-pyrrolo[2,3-d]pyrimidine, is a white solid that can be obtained by iodine reaction of 4-chloro-7h-pyrrole [2,3-d] pyrimidine with NIS.

Synthesis

4-chloro-7h-pyrrole [2,3-d] pyrimidine (8.0 g, 52.32 mmol, 1.0 eq) was dissolved in DMF(40 mL) and NIS(15.7g, 57.55 mmol, 1.1eq) was added at 0℃. After stirring at room temperature overnight, 200 mL of saturated Na2S2O3 solution was added. The mixture was filtered, washed with water three times, and vacuum drying, to obtain 4-Chloro-5-iodo-7H-pyrrol[2,3-d]pyrimidine.

References

[1] Patent: US2005/107312, 2005, A1
[2] Patent: US2005/215510, 2005, A1
[3] Patent: US2005/215511, 2005, A1
[4] Patent: US2005/215511, 2005, A1
[5] Patent: WO2012/158795, 2012, A1. Location in patent: Page/Page column 100

4-Chloro-5-iodo-7H-pyrrol[2,3-d]pyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Chloro-5-iodo-7H-pyrrol[2,3-d]pyrimidine Suppliers

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View Lastest Price from 4-Chloro-5-iodo-7H-pyrrol[2,3-d]pyrimidine manufacturers

Dideu Industries Group Limited
Product
4-Chloro-5-iodo-7H-pyrrol[2,3-d]pyrimidine 123148-78-7
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-12-06
Career Henan Chemical Co
Product
4-Chloro-5-iodo-7H-pyrrol[2,3-d]pyrimidine 123148-78-7
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
Customized
Release date
2019-05-25

123148-78-7, 4-Chloro-5-iodo-7H-pyrrol[2,3-d]pyrimidineRelated Search:

2,4-DICHLORO-5H-PYRROLO[3,2-D]PYRIMIDINE Pyrrolo[2,3-d]pyrimidin-4-ol N4-Benzoylcytosine 4-CHLORO-7-TOSYL-7H-PYRROLO[2,3-D]PYRIMIDINE 4-Aminopyrazolo[3,4-d]pyrimidine 5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine Povidone iodine Pyrimidine Clioquinol Difluorochloromethane Propanamide, N-(4-chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-2-yl)-2,2-dimethyl- DEAZAPURINE 4-chloro-6-iodo-7H-pyrrolo[2,3-d]pyrimidine 7-DEAZAPURINE 4-CHLORO-7-CYCLOPENTYL-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDINE 4-CHLORO-5-IODO-7-METHYL-7H-PYRROLO[2,3-D]PYRIMIDINE 4-Chloro-5-iodo-7H-pyrrol[2,3-d]pyrimidine

  • 4-Chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidine
  • 4-CHLORO-5-IODO-7H-PYRROL[2,3]PYRIMIDINE
  • 4-CHLORO-5-IODO-1H-PYRROLO [2,3-D] PYRIMIDINE
  • 4-Chloro-5-iodo-7H-pyrrol[2,3-d]pyrimidine
  • 6-Chloro-7-iodo-7-deazapurine
  • 4-Chloro-5-iodo-1H-pyrrol...
  • JR-13973, 4-Chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidine, 95%
  • 7H-Pyrrolo[2,3-d]pyriMidine, 4-chloro-5-iodo-
  • 6-Chloro-7-iodo-7-deazapurine,96%
  • 4-Chloro-5-iodo-7H-pyrrol[2,3-d]pyrimidine 6-Chloro-7-iodo-7-deazapurine
  • 6-Chloro-7-iodo-deazapurine
  • EOS-62121
  • 5-Iodo-4-chloro-7H-pyrrol[2,3-d]pyrimidine
  • 6-Chloro-7-iodo-7-deazapurine &gt
  • 4-Chloro-5-iodo-7H-pyrrol[2,3-d]pyrimidine ISO 9001：2015 REACH
  • 4-CHLORO-5-IODO-7H-PYRROLO[2,3-d]PYRIMIDINE ( IPN)
  • Name 6-Chloro-7-iodo-7-deazapurine
  • 123148-78-7
  • Heterocycle-Pyrimidine series