ChemicalBook > CAS DataBase List > Methyl piperidine-4-carboxylate hydrochloride

Methyl piperidine-4-carboxylate hydrochloride

Product Name
Methyl piperidine-4-carboxylate hydrochloride
CAS No.
7462-86-4
Chemical Name
Methyl piperidine-4-carboxylate hydrochloride
Synonyms
Nsc402200;Methyl Isonipecotate HCl;Methyl 4-piperidinecarboxylate;METHYL ISONIPECOTATE HYDROCHLORIDE;METHYL 4-PIPERIDINECARBOXYLATE HCL;METHYL PIPERIDINE-4-CARBOXYLATE HCL;Methyl 4-piperidinate hydrochloride;METHYL ISONIPECOTINATE HYDROCHLORIDE;methyl piperidin-1-ium-4-carboxylate;Methyl 4-Piperidinecarboxylic Ester HCl
CBNumber
CB5121436
Molecular Formula
C7H14ClNO2
Formula Weight
179.64
MOL File
7462-86-4.mol
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Methyl piperidine-4-carboxylate hydrochloride Property

Melting point:
160°C
Boiling point:
85-90 °C
Density 
1.06
refractive index 
1.465
Flash point:
89 °C
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
Appearance
White to off-white Solid
CAS DataBase Reference
7462-86-4(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
M321465
Product name
MethylPiperidine-4-carboxylateHydrochloride
Packaging
50mg
Price
$45
Updated
2021/12/16
Matrix Scientific
Product number
083556
Product name
Methyl piperidine-4-carboxylate hydrochloride
Purity
97%
Packaging
100g
Price
$88
Updated
2021/12/16
Matrix Scientific
Product number
083556
Product name
Methyl piperidine-4-carboxylate hydrochloride
Purity
97%
Packaging
500g
Price
$298
Updated
2021/12/16
Ark Pharm
Product number
AK116971
Product name
Methylpiperidine-4-carboxylatehydrochloride
Purity
98%
Packaging
10g
Price
$11
Updated
2021/12/16
AK Scientific
Product number
B108
Product name
Methylisonipecotatehydrochloride
Packaging
5g
Price
$14
Updated
2021/12/16
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Methyl piperidine-4-carboxylate hydrochloride Chemical Properties,Usage,Production

Uses

Methyl piperidine-4-carboxylate hydrochloride is a crucial compound that could be used as a pharmaceutical intermediate in pharmaceutical synthesis and scientific research.

Synthesis

124443-68-1

7462-86-4

General procedure for the synthesis of methyl 4-piperidinecarboxylate hydrochloride from methyl 1-tert-butoxycarbonyl-4-piperidinecarboxylate: To a dichloromethane (DCM, 3 mL) solution of methyl 1-tert-butoxycarbonyl-4-piperidinecarboxylate (2.16 g, 8.88 mmol) was added a solution of ethyl acetate (EtOAc, 6 mL) of 4 M hydrochloric acid. The reaction mixture was stirred at room temperature for 1.5 h. Subsequent removal of the solvent by concentration under reduced pressure afforded methyl 4-piperidinecarboxylate hydrochloride as a white solid (1.59 g, 99% yield). The product was characterized by 1H NMR (400 MHz, CD3OD): δ 3.73 (s, 3H), 3.44-3.39 (m, 2H), 3.15-3.09 (m, 2H), 2.82-2.77 (m, 1H), 2.21-2.16 (m, 2H), 1.99-1.89 (m, 2H); MS-ESI: m/z 144.2 [M + H - HCl]+.

References

[1] Patent: WO2016/34134, 2016, A1. Location in patent: Paragraph 00373
[2] Patent: CN105399698, 2016, A. Location in patent: Paragraph 0920-0923

Methyl piperidine-4-carboxylate hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Methyl piperidine-4-carboxylate hydrochloride manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
Methyl 4-piperidinecarboxylate 7462-86-4
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-05
Anhui Dexinjia Biopharm Co., Ltd
Product
Methyl piperidine-4-carboxylate HCl 7462-86-4
Price
US $15.00-50.00/kg
Min. Order
1kg
Purity
NLT98%
Supply Ability
5 ton per month
Release date
2023-04-02
Henan Bao Enluo International TradeCo.,LTD
Product
Methyl 4-piperidinecarboxylate 7462-86-4
Price
US $50.00/kg
Min. Order
1kg
Purity
99.9%
Supply Ability
10000MT
Release date
2023-08-01

7462-86-4, Methyl piperidine-4-carboxylate hydrochloride Related Search:


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