Methyl piperidine-4-carboxylate hydrochloride
- Product Name
- Methyl piperidine-4-carboxylate hydrochloride
- CAS No.
- 7462-86-4
- Chemical Name
- Methyl piperidine-4-carboxylate hydrochloride
- Synonyms
- Nsc402200;Methyl Isonipecotate HCl;Methyl 4-piperidinecarboxylate;METHYL ISONIPECOTATE HYDROCHLORIDE;METHYL 4-PIPERIDINECARBOXYLATE HCL;METHYL PIPERIDINE-4-CARBOXYLATE HCL;Methyl 4-piperidinate hydrochloride;METHYL ISONIPECOTINATE HYDROCHLORIDE;methyl piperidin-1-ium-4-carboxylate;Methyl 4-Piperidinecarboxylic Ester HCl
- CBNumber
- CB5121436
- Molecular Formula
- C7H14ClNO2
- Formula Weight
- 179.64
- MOL File
- 7462-86-4.mol
Methyl piperidine-4-carboxylate hydrochloride Property
- Melting point:
- 160°C
- Boiling point:
- 85-90 °C
- Density
- 1.06
- refractive index
- 1.465
- Flash point:
- 89 °C
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- Appearance
- White to off-white Solid
- CAS DataBase Reference
- 7462-86-4(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- M321465
- Product name
- MethylPiperidine-4-carboxylateHydrochloride
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 083556
- Product name
- Methyl piperidine-4-carboxylate hydrochloride
- Purity
- 97%
- Packaging
- 100g
- Price
- $88
- Updated
- 2021/12/16
- Product number
- 083556
- Product name
- Methyl piperidine-4-carboxylate hydrochloride
- Purity
- 97%
- Packaging
- 500g
- Price
- $298
- Updated
- 2021/12/16
- Product number
- AK116971
- Product name
- Methylpiperidine-4-carboxylatehydrochloride
- Purity
- 98%
- Packaging
- 10g
- Price
- $11
- Updated
- 2021/12/16
- Product number
- B108
- Product name
- Methylisonipecotatehydrochloride
- Packaging
- 5g
- Price
- $14
- Updated
- 2021/12/16
Methyl piperidine-4-carboxylate hydrochloride Chemical Properties,Usage,Production
Uses
Methyl piperidine-4-carboxylate hydrochloride is a crucial compound that could be used as a pharmaceutical intermediate in pharmaceutical synthesis and scientific research.
Synthesis
124443-68-1
7462-86-4
General procedure for the synthesis of methyl 4-piperidinecarboxylate hydrochloride from methyl 1-tert-butoxycarbonyl-4-piperidinecarboxylate: To a dichloromethane (DCM, 3 mL) solution of methyl 1-tert-butoxycarbonyl-4-piperidinecarboxylate (2.16 g, 8.88 mmol) was added a solution of ethyl acetate (EtOAc, 6 mL) of 4 M hydrochloric acid. The reaction mixture was stirred at room temperature for 1.5 h. Subsequent removal of the solvent by concentration under reduced pressure afforded methyl 4-piperidinecarboxylate hydrochloride as a white solid (1.59 g, 99% yield). The product was characterized by 1H NMR (400 MHz, CD3OD): δ 3.73 (s, 3H), 3.44-3.39 (m, 2H), 3.15-3.09 (m, 2H), 2.82-2.77 (m, 1H), 2.21-2.16 (m, 2H), 1.99-1.89 (m, 2H); MS-ESI: m/z 144.2 [M + H - HCl]+.
References
[1] Patent: WO2016/34134, 2016, A1. Location in patent: Paragraph 00373
[2] Patent: CN105399698, 2016, A. Location in patent: Paragraph 0920-0923
Methyl piperidine-4-carboxylate hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Methyl piperidine-4-carboxylate hydrochloride manufacturers
- Product
- Methyl 4-piperidinecarboxylate 7462-86-4
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-05
- Product
- Methyl piperidine-4-carboxylate HCl 7462-86-4
- Price
- US $15.00-50.00/kg
- Min. Order
- 1kg
- Purity
- NLT98%
- Supply Ability
- 5 ton per month
- Release date
- 2023-04-02
- Product
- Methyl 4-piperidinecarboxylate 7462-86-4
- Price
- US $50.00/kg
- Min. Order
- 1kg
- Purity
- 99.9%
- Supply Ability
- 10000MT
- Release date
- 2023-08-01