Uses
ChemicalBook > CAS DataBase List > Ethyl 1,3-dimethylpyrazole-5-carboxylate

Ethyl 1,3-dimethylpyrazole-5-carboxylate

Uses
Product Name
Ethyl 1,3-dimethylpyrazole-5-carboxylate
CAS No.
5744-40-1
Chemical Name
Ethyl 1,3-dimethylpyrazole-5-carboxylate
Synonyms
AKOS PAO-0382;BUTTPARK 91\11-01;RARECHEM AL BI 1315;1,3-dimethyl-5-ethoxycarbonylpyrazole;ETHYL 1,3-DIMETHYLPYRAZOLE-5-CARBOXYLATE;Ethyl 1,3-DiMethyl-5-pyrazolecarboxylate;ethyl 2,5-dimethylpyrazole-3-carboxylate;Ethyl1,3-Dimethylpyrazole-5-carboxylate>Ethyl 1,3-dimethylpyrazole-5-carboxylate 95%;ETHYL 1,3-DIMETHYL-1H-PYRAZOLE-5-CARBOXYLATE
CBNumber
CB5145081
Molecular Formula
C8H12N2O2
Formula Weight
168.19
MOL File
5744-40-1.mol
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Ethyl 1,3-dimethylpyrazole-5-carboxylate Property

Melting point:
40-42 °C
Boiling point:
80°C 1mm
Density 
1.12±0.1 g/cm3(Predicted)
refractive index 
1.4790 to 1.4830
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
clear liquid
pka
1.03±0.10(Predicted)
color 
Light yellow to Yellow to Orange
InChI
InChI=1S/C8H12N2O2/c1-4-12-8(11)7-5-6(2)9-10(7)3/h5H,4H2,1-3H3
InChIKey
ZYSGPOXVDOROJU-UHFFFAOYSA-N
SMILES
N1(C)C(C(OCC)=O)=CC(C)=N1
CAS DataBase Reference
5744-40-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
22-36/37/38
Safety Statements 
24/25-36/37/39-26-23
HazardClass 
IRRITANT
HS Code 
29331990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
JRD0206
Product name
Ethyl 1,3-dimethyl-1H-pyrazole-5-carboxylate
Purity
Aldrich
Packaging
1g
Price
$107
Updated
2025/07/31
TCI Chemical
Product number
E1001
Product name
Ethyl 1,3-Dimethylpyrazole-5-carboxylate
Purity
>96.0%(GC)
Packaging
1g
Price
$59
Updated
2025/07/31
TRC
Product number
E917410
Product name
Ethyl 1,3-dimethyl-1H-pyrazole-5-carboxylate
Packaging
500mg
Price
$65
Updated
2021/12/16
AK Scientific
Product number
J50964
Product name
Ethyl 1,3-dimethyl-1H-pyrazole-5-carboxylate
Packaging
1g
Price
$10
Updated
2021/12/16
Matrix Scientific
Product number
024550
Product name
Ethyl 1,3-dimethylpyrazole-5-carboxylate
Packaging
1g
Price
$12
Updated
2021/12/16
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Ethyl 1,3-dimethylpyrazole-5-carboxylate Chemical Properties,Usage,Production

Uses

1,3-Dimethyl-1H-pyrazole-5-carboxylic acid ethyl ester is a representative compound of pyrazole derivatives. By modifying its structure and introducing different substituents into the pyrazole ring structure, it is expected that pyrazole derivatives with better performance can be obtained.

Chemical Properties

Colorless to light yellow liqui

Synthesis

4027-57-0

616-38-6

5744-40-1

The general procedure for the synthesis of ethyl 1,3-dimethyl-1hydro-pyrazole-5-carboxylate from ethyl 3-methylpyrazole-5-carboxylate and dimethyl carbonate is as follows: 0.1 mol ethyl 3-methyl-5-pyrazolecarboxylate, 0.055 mol dimethyl carbonate (DMC), 100 mL xylene, and 2.0 g Cs2CO3 were mixed, and the reaction was carried out at 130?140°C for 8 hours. Upon completion of the reaction, the mixture was cooled to room temperature and the solvent was removed by rotary evaporation to afford ethyl 1,3-dimethyl-5-pyrazolecarboxylate as an oil. The product was quantitatively analyzed by high performance liquid chromatography (HPLC) with a purity of 97.7% and a yield of 85.8%.

References

[1] Patent: CN107216288, 2017, A. Location in patent: Paragraph 0039; 0040; 0041; 0042

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View Lastest Price from Ethyl 1,3-dimethylpyrazole-5-carboxylate manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
Ethyl 1,3-dimethylpyrazole-5-carboxylate 5744-40-1
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-09-23
Henan Fengda Chemical Co., Ltd
Product
Ethyl 1,3-dimethylpyrazole-5-carboxylate 5744-40-1
Price
US $5.00-0.10/KG
Min. Order
1KG
Purity
98%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-09
Zhuozhou Wenxi import and Export Co., Ltd
Product
Ethyl 1,3-dimethylpyrazole-5-carboxylate 5744-40-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10

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