ChemicalBook > CAS DataBase List > 4-METHYL-6-CHLORO PYRIMIDINE

4-METHYL-6-CHLORO PYRIMIDINE

Product Name
4-METHYL-6-CHLORO PYRIMIDINE
CAS No.
3435-25-4
Chemical Name
4-METHYL-6-CHLORO PYRIMIDINE
Synonyms
4-CHLORO-6-METHYLPYRIMIDINE;AKOS BBS-00002134;6-Chloro-4-methylpyrimidine;4-METHYL-6-CHLORO PYRIMIDINE;4-Chloro-6-methyl-1,3-diazine;Pyrimidine, 4-chloro-6-methyl-;4-Chloro-6-methylpyrimidine,97%;4-chloro-6-methylpyrimidine(SALTDATA: FREE);4-METHYL-6-CHLORO PYRIMIDINE ISO 9001：2015 REACH;Pyrimidine, 4-chloro-6-methyl- (6CI,7CI,8CI,9CI)
CBNumber
CB5161786
Molecular Formula
C5H5ClN2
Formula Weight
128.56
MOL File
3435-25-4.mol
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4-METHYL-6-CHLORO PYRIMIDINE Property

Melting point:
151-152℃
Boiling point:
195℃
Density 
1.234
Flash point:
90℃
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
Solid
pka
0.83±0.17(Predicted)
color 
Pale yellow
Water Solubility 
Slightly soluble in water.
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Safety

HS Code 
2933599590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC
Product number
C602028
Product name
4-Chloro-6-methylpyrimidine
Packaging
500mg
Price
$75
Updated
2021/12/16
Apolloscientific
Product number
OR60081
Product name
4-Chloro-6-methylpyrimidine
Packaging
1g
Price
$29
Updated
2021/12/16
Matrix Scientific
Product number
072166
Product name
4-Chloro-6-methylpyrimidine
Purity
95+%
Packaging
1g
Price
$39
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0013137
Product name
4-CHLORO-6-METHYLPYRIMIDINE
Purity
95.00%
Packaging
1G
Price
$785.4
Updated
2021/12/16
Matrix Scientific
Product number
072166
Product name
4-Chloro-6-methylpyrimidine
Purity
95+%
Packaging
5g
Price
$118
Updated
2021/12/16
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4-METHYL-6-CHLORO PYRIMIDINE Chemical Properties,Usage,Production

Uses

It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuffs.

Synthesis

1193-21-1

75-16-1

3435-25-4

To a solution of 4,6-dichloropyrimidine (1.0 g, 6.71 mmol) in tetrahydrofuran (30 mL) was added sequentially 1-methyl-2-pyrrolidinone (3.2 mL, 6.71 mmol), iron(III) acetylacetonate (0.119 g, 0.336 mmol) and methylmagnesium bromide (2.237 mL, 6.71 mmol). The reaction mixture was stirred at room temperature for 3 h. After completion of the reaction, the reaction was quenched with water and extracted with ethyl acetate (100 mL). The organic layer was separated and concentrated under reduced pressure to remove the solvent. The residue was purified by silica gel column chromatography (eluent: 20% ethyl acetate/hexane) to afford 4-chloro-6-methylpyrimidine (0.6 g, 3.08 mmol, 46% yield) as a colorless gelatinous liquid.LC-MS (ESI) analysis showed m/z 129.0 [M+H]+ (calculated value C5H6ClN2: 129.0); LC/MS retention time ( Method D): 1.36 min.

References

[1] Patent: WO2017/59085, 2017, A1. Location in patent: Page/Page column 403; 404

4-METHYL-6-CHLORO PYRIMIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-METHYL-6-CHLORO PYRIMIDINE Suppliers

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View Lastest Price from 4-METHYL-6-CHLORO PYRIMIDINE manufacturers

Henan Fengda Chemical Co., Ltd
Product
4-Chloro-6-methylpyrimidine 3435-25-4
Price
US $200.00-1.00/KG
Min. Order
1KG
Purity
99%, 99.5% Sublimated
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-30
Shanghai Rlavie Technology Co ltd
Product
4-Chloro-6-MethylpyriMidine 3435-25-4
Price
US $0.00-0.00/kg
Min. Order
0.0001kg
Purity
98%min
Supply Ability
100kgs/month
Release date
2022-05-10
Dideu Industries Group Limited
Product
4-METHYL-6-CHLORO PYRIMIDINE 3435-25-4
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-12-06

3435-25-4, 4-METHYL-6-CHLORO PYRIMIDINERelated Search:

4-Chloro-6-methylquinoline 2-AMINO-4-CHLORO-6-PHENYLPYRIMIDINE 4-CHLORO-5,6-DIMETHYL-2-(TRIFLUOROMETHYL)PYRIMIDINE 2,4-Dichloro-6-methyl-5-nitropyrimidine 4-Chloro-6-methyl-2-(methylthio)pyrimidine 2-Amino-4-chloro-6-methylpyrimidine 2,4-Dichloro-6-methylpyrimidine 5-Bromo-2,4-dichloro-6-methylpyrimidine 5-Amino-4,6-dichloro-2-methylpyrimidine 2-Chloro-5-methylpyrimidine 2,4,6-Trichloro-5-methylpyrimidine 4-Amino-6-chloro-2-methylpyrimidine 2-Chloro-6-methylpyrimidine-4,5-diamine 4-Pyrimidinamine, 6-chloro-5-methyl- (9CI) 2,4-Dichloro-5-methylpyrimidine 2-Amino-4,6-dichloro-5-methylpyrimidine 4-Amino-2-chloro-5-methylpyrimidine 4-CHLORO-6-(4-CHLOROPHENYL)-2-(3-PYRIDINYL)-5-PYRIMIDINECARBONITRILE

  • AKOS BBS-00002134
  • Pyrimidine, 4-chloro-6-methyl- (6CI,7CI,8CI,9CI)
  • 4-chloro-6-methylpyrimidine(SALTDATA: FREE)
  • 6-Chloro-4-methylpyrimidine
  • 4-Chloro-6-methyl-1,3-diazine
  • Pyrimidine, 4-chloro-6-methyl-
  • 4-Chloro-6-methylpyrimidine,97%
  • 4-METHYL-6-CHLORO PYRIMIDINE ISO 9001：2015 REACH
  • 4-METHYL-6-CHLORO PYRIMIDINE
  • 4-CHLORO-6-METHYLPYRIMIDINE
  • 3435-25-4
  • Heterocycle-Pyrimidine series
  • PYRIMIDINE
  • Halides
  • Pyrazines, Pyrimidines & Pyridazines