ChemicalBook > CAS DataBase List > 1,3-Dichloro-4-fluorobenzene

1,3-Dichloro-4-fluorobenzene

Product Name
1,3-Dichloro-4-fluorobenzene
CAS No.
1435-48-9
Chemical Name
1,3-Dichloro-4-fluorobenzene
Synonyms
2,4-DICHLORO-1-FLUOROBENZENE;2,4-DICHLOROFLUOROBENZENE;2,4-Dichlorofluorobenzene 99%;2,4-Dichloro-1-fluor;2,4-Dichlorofluobenzene;1,3-DICHLOROFLUOROBENZENE;2,4- twochlorofluorobenzene;2,4-Dichlorofluorobenzene99%;1,3-DICHLORO-4-FLUOROBENZENE;2,4-Dichlorofluorobenzene>
CBNumber
CB5257704
Molecular Formula
C6H3Cl2F
Formula Weight
164.99
MOL File
1435-48-9.mol
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1,3-Dichloro-4-fluorobenzene Property

Melting point:
-23 °C
Boiling point:
172-174 °C(lit.)
Density 
1.409 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.525(lit.)
Flash point:
98 °F
storage temp. 
Sealed in dry,Room Temperature
form 
clear liquid
color 
Colorless to Light yellow to Light orange
Specific Gravity
1.409
Water Solubility 
insoluble
BRN 
2500791
InChI
InChI=1S/C6H3Cl2F/c7-4-1-2-6(9)5(8)3-4/h1-3H
InChIKey
BDJZCCWUSOZUQG-UHFFFAOYSA-N
SMILES
C1(F)=CC=C(Cl)C=C1Cl
CAS DataBase Reference
1435-48-9(CAS DataBase Reference)
NIST Chemistry Reference
1,3-Dichloro-4-fluorobenzene(1435-48-9)
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Safety

Hazard Codes 
Xn,N,Xi
Risk Statements 
22-38-48/20/22-51/53-10-36/37/38
Safety Statements 
36/37-61-16-36-26
RIDADR 
UN 1993 3/PG 3
WGK Germany 
3
Hazard Note 
Irritant
HazardClass 
9
PackingGroup 
III
HS Code 
29039990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

H227Combustible liquid

H302Harmful if swallowed

H315Causes skin irritation

H373May cause damage to organs through prolonged or repeated exposure

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P391Collect spillage. Hazardous to the aquatic environment

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
D2059
Product name
2,4-Dichlorofluorobenzene
Purity
>96.0%(GC)
Packaging
25g
Price
$29
Updated
2025/07/31
TCI Chemical
Product number
D2059
Product name
2,4-Dichlorofluorobenzene
Purity
>96.0%(GC)
Packaging
500g
Price
$214
Updated
2025/07/31
TRC
Product number
D438810
Product name
2,4-Dichlorofluorobenzene
Packaging
2.5g
Price
$75
Updated
2021/12/16
AK Scientific
Product number
J56009
Product name
2,4-Dichlorofluobenzene
Packaging
5g
Price
$10
Updated
2021/12/16
Matrix Scientific
Product number
005278
Product name
2,4-Dichlorofluorobenzene
Purity
99%
Packaging
5g
Price
$10
Updated
2021/12/16
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1,3-Dichloro-4-fluorobenzene Chemical Properties,Usage,Production

Chemical Properties

Clear colourless to yellow liquid

Uses

1, 3-dichloro-4-fluorobenzene is a multifunctional chemical reagent. Its benzene ring structure formula contains fluorine and chlorine functional groups and can be used in various reaction systems. It is widely applied in the field of organic synthesis.

Synthesis

350-30-1

1435-48-9

The general procedure for the synthesis of 2,4-dichlorofluorobenzene from 3-chloro-4-fluoronitrobenzene is as follows: 240 g (1.37 mol) of 3-chloro-4-fluoronitrobenzene was added to a 250 ml four-necked flask and the temperature of the reaction system was raised to 170°C. The temperature of the reaction system was raised to 170°C. The reaction system was then purged with dry chlorine. Dry chlorine gas was slowly passed in the temperature range of 170 to 180 °C. The reaction process was carried out by distillation for 8 hours and the distillate was collected. The distillate was subsequently washed with water and then with alkali to a weakly basic pH. The organic phase was separated and purified by distillation, resulting in 207 g of 2,4-dichlorofluorobenzene with 99.8% purity and 91.7% yield.

References

[1] Patent: CN102249881, 2016, B. Location in patent: Paragraph 0020; 0075-0076
[2] Recueil des Travaux Chimiques des Pays-Bas, 1932, vol. 51, p. 98,109

1,3-Dichloro-4-fluorobenzene Preparation Products And Raw materials

Raw materials

4-Nitrobenzoyl chloride 3-Chloro-4-fluoroaniline Fluorobenzene 5-Chloro-2-fluoronitrobenzene 2,4-Dinitrofluorobenzene 3-Chloro-4-fluoronitrobenzene

Preparation Products

3-BROMO-2,4-DICHLORO-5-FLUORONITROBENZENE 2,4-Dichloro-5-fluoronitrobenzene Ciprofloxacin hydrochloride 1-(2,4-DICHLORO-5-FLUORO-3-METHOXYPHENYL)ETHANONE 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-4-oxoquinoline-3-carboxylic acid 2,4-DICHLORO-5-FLUORO-3-METHOXYNITRO-BENZENE 2,4-DICHLORO-5-FLUORO-3-METHOXYBENZOIC ACID 2,4-Dichloro-5-fluoroacetophenone 2,4-Dichloro-5-fluoro-3-methoxybenzoyl chloride 1-AMINO-2,4-DICHLORO-5-FLUORO-3-METHOXYBENZENE Ciprofloxacin 2,4-Dichloro-5-fluorobenzoic acid 3-BROMO-2,6-DICHLORO-5-FLUORO-1-METHOXYBENZENE
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1,3-Dichloro-4-fluorobenzene Suppliers

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View Lastest Price from 1,3-Dichloro-4-fluorobenzene manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
1,3-Dichloro-4-fluorobenzene 1435-48-9
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-12-10
Henan Fengda Chemical Co., Ltd
Product
1,3-Dichloro-4-fluorobenzene 1435-48-9
Price
US $100.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-26
Anhui Zhongda Biotechnology Co., Ltd
Product
1,3-Dichloro-4-fluorobenzene 1435-48-9
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100T
Release date
2023-10-31

1435-48-9, 1,3-Dichloro-4-fluorobenzeneRelated Search:

Florfenicol 1,3-Difluorobenzene 4-Fluorobenzonitrile Fluorobenzene Transfluthrin 4,6-Dichloropyrimidine 1,2-Dichloroethane 4-Fluorobenzaldehyde Dichloroacetic acid 2,6-dichloro-1-fluorobenzene,1,3-Dichloro-2-fluorobenzene, 98+%,1,3-DICHLORO-2-FLUOROBENZENE Teflubenzuron 2,4-Dichloro-5-fluoroacetophenone 2,4-DICHLORO-5-FLUOROBENZALDEHYDE, 97 2,4-Dichloro-5-fluoronitrobenzene 1,3,5-Trichloro-2,4,6-trifluorobenzene 1,3-DICHLORO-2,4,6-TRIFLUOROBENZENE 1,3-DICHLORO-2,4-DIFLUOROBENZENE METHYL 2,4-DICHLORO-5-FLUOROBENZOATE

  • 2,4-Dichlorofluorobenzene 99%
  • 2,4-Dichlorofluorobenzene99%
  • DCFB 2,4-Dichlorofluorobenzen
  • 1,3-Dichloro-4-fluorobenzene,99%
  • 2,4-DICHLOROFLUOROBENZENECIPROFLOXACIN
  • N-[4-(trichloromethylthio)sulfonylphenyl]acetamide
  • 2,4-Dichloro-1-fluor
  • 2,4-Dichlorofluobenzene
  • 2,4- twochlorofluorobenzene
  • Benzene,2,4-dichloro-1-fluoro-
  • 2,4-DICHLORO-1-FLUOROBENZENE
  • 2,4-DICHLOROFLUOROBENZENE
  • 2,4-DichloroFluorobenzene99.5%
  • 1,3-DICHLORO-4-FLUOROBENZENE
  • 1,3-DICHLOROFLUOROBENZENE
  • 2,4-Dichlorofluorobenzene&gt
  • 1,3-Dichloro-4-fluorobenzene ISO 9001：2015 REACH
  • 1435-48-9
  • 1435-38-9
  • Aryl
  • Building Blocks
  • Organic Building Blocks
  • Halogenated Hydrocarbons
  • C6
  • Aromatic Hydrocarbons (substituted) & Derivatives
  • Fluorobenzene
  • Chlorine Compounds
  • Fluorine Compounds
  • Aryl
  • Halogenated Hydrocarbons
  • bc0001
  • OLED
  • C6