ChemicalBook > CAS DataBase List > 5,6-Dichloronicotinic acid

5,6-Dichloronicotinic acid

Product Name
5,6-Dichloronicotinic acid
CAS No.
41667-95-2
Chemical Name
5,6-Dichloronicotinic acid
Synonyms
2,3-dichloropyridine-5-carboxylic acid;5,6-DichL;5,6-Dichloro;TIMTEC-BB SBB003623;Avatrhopal Impurity 45;5,6-DICHLORONICOTINIC A;Avatrombopag Impurity 10;Avatroposide impurities16;5,6-DICHLORONICOTINIC ACID;5,6-DichloronicotinicAcid>
CBNumber
CB5261891
Molecular Formula
C6H3Cl2NO2
Formula Weight
192
MOL File
41667-95-2.mol
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5,6-Dichloronicotinic acid Property

Melting point:
164-168 °C(lit.)
Boiling point:
342.1±37.0 °C(Predicted)
Density 
1.612±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
2.87±0.10(Predicted)
form 
Powder
color 
White to beige to tan
BRN 
383740
InChI
InChI=1S/C6H3Cl2NO2/c7-4-1-3(6(10)11)2-9-5(4)8/h1-2H,(H,10,11)
InChIKey
RNRLTTNKVLFZJS-UHFFFAOYSA-N
SMILES
C1=NC(Cl)=C(Cl)C=C1C(O)=O
CAS DataBase Reference
41667-95-2(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-24/25-36-26
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
340219
Product name
5,6-Dichloropyridine-3-carboxylic acid
Purity
96%
Packaging
5g
Price
$26
Updated
2023/06/20
TCI Chemical
Product number
D2401
Product name
5,6-Dichloronicotinic Acid
Purity
>98.0%(T)
Packaging
5g
Price
$56
Updated
2024/03/01
TCI Chemical
Product number
D2401
Product name
5,6-Dichloronicotinic Acid
Purity
>98.0%(T)
Packaging
25g
Price
$191
Updated
2024/03/01
Alfa Aesar
Product number
B25586
Product name
5,6-Dichloronicotinic acid, 98+%
Packaging
25g
Price
$209
Updated
2021/12/16
Alfa Aesar
Product number
B25586
Product name
5,6-Dichloronicotinic acid, 98+%
Packaging
5g
Price
$62.7
Updated
2021/12/16
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5,6-Dichloronicotinic acid Chemical Properties,Usage,Production

Chemical Properties

white to off-white crystalline powder

Uses

5,6-Dichloronicotinic acid is a dihalonicotinic acid. It is used in the preparation of 5-chloro-6-iodonicotinic acid by iodine displacement.

Application

5,6-Dichloronicotinic acid is a compound that can be synthesized by reacting methyl ketones with chloroacetic acid. It is used in the synthesis of maleic anhydride and has been shown to inhibit the catalysis of acetylcholine chloride. It has also been shown to have an inhibitory effect on Alzheimer's disease. The kinetic mechanism for this inhibition occurs through the hydrolysis step of 5,6-Dichloronicotinic acid by magnesium chloride in hexane solution. The reactive acylation reaction proceeds when it reacts with acetic anhydride in the presence of pyridine.

5,6-Dichloronicotinic acid Preparation Products And Raw materials

Raw materials

Preparation Products

2,3-DICHLOROPYRIDINE-5-CARBONYL CHLORIDE 5,6-DICHLORONICOTINIC ACID ETHYL ESTER
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5,6-Dichloronicotinic acid Suppliers

Americas 1 Belgium 1 Canada 1 China 299 Europe 3 France 1 Germany 5 India 35 Ireland 1 Japan 1 Jordan 1 Slovakia 1 Switzerland 1 Ukraine 3 United Kingdom 17 United States 45 Global 416
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View Lastest Price from 5,6-Dichloronicotinic acid manufacturers

Zison Pharmaceutical (Shandong) Co., Ltd.
Product
5,6-Dichloronicotinic acid 41667-95-2
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
≥98% by HPLC
Supply Ability
50kg/month
Release date
2023-01-05
Hebei Weibang Biotechnology Co., Ltd
Product
5,6-Dichloronicotinic acid 41667-95-2
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-26
Hebei Yanxi Chemical Co., Ltd.
Product
5,6-Dichloronicotinic acid 41667-95-2
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20 tons
Release date
2023-11-13

41667-95-2, 5,6-Dichloronicotinic acidRelated Search:

Thionyl chloride Sodium dichloroisocyanurate Dichlorodimethylsilane Isonicotinic acid 6-Chloronicotinic acid 2-Chloronicotinic acid N,N-Dimethylacetamide 2,6-Dichloroisonicotinic acid Quinclorac 2,6-Dichloro-5-fluoronicotinic acid 4-Chloronicotinic acid EPA Dichloroethane 2-chloro-5-cyanopyridine 2-Mercaptonicotinic acid 6-Aminonicotinic acid 2,6-DICHLORONICOTINIC ACID 98%,2 6-DICHLORONICOTINIC ACID TECH. 90%,2,6-DICHLORONICOTINIC ACID 2,5-DICHLORONICOTINIC ACID

  • 5,6-DICHLORO-3-PYRIDINECARBOXYLIC ACID
  • 5,6-DICHLORONICOTINIC ACID
  • 5,6-DICHLOROPYRIDINE-3-CARBOXYLIC ACID
  • TIMTEC-BB SBB003623
  • 5,6-Dichloropyridine-3-carboxylicacid,96%
  • 5,6-Dichloro
  • 5,6-DICHLORONICOTINIC ACID 98+%
  • 5,6-Dichloronicotinic acid, 5,6-Dichloropyridine-3-carboxylic acid
  • 5,6-Dichloropyridine-3-carboxylic acid, 98+%
  • 5,6-DICHLORONICOTINIC A
  • 5,6-Dichloropyridine-3-carboxylic acid, 5-Carboxy-2,3-dichloropyridine
  • 2,3-dichloropyridine-5-carboxylic acid
  • 5,6-Dichloronicotinic acid 97%
  • 5,6-DichloronicotinicAcid&gt
  • 5,6-DichL
  • 3-Pyridinecarboxylic acid, 5,6-dichloro-
  • Avatrombopag Impurity 10
  • 5,6-Dichloronicotinic acid ISO 9001：2015 REACH
  • Avatroposide impurities16
  • (4-cyclohexylpiperazin-1-yl)(5,6-dichloropyridin-3-yl)methanone
  • Avatrhopal Impurity 45
  • 41667-95-2
  • 1667-95-2
  • Pyridines
  • Heterocyclic Building Blocks
  • Halogenated Heterocycles
  • Building Blocks
  • Chloropyridines
  • Halopyridines
  • Heterocycle-Pyridine series
  • Chloropyridines
  • Halopyridines
  • Pyridine
  • Building Blocks
  • C5 to C6
  • C6 to C7
  • Chemical Synthesis
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • Pyridines
  • pharmacetical
  • Organic acids
  • Pyridines, Pyrimidines, Purines and Pteredines
  • Intermediate