DBCO-PEG4-maleimide

Product Name: DBCO-PEG4-maleimide
CAS No.: 1480516-75-3
Chemical Name: DBCO-PEG4-maleimide
Synonyms: DBCO-PEG4-MAL;DBCO-dPEG??-MAL;DBCO-NHCO-PEG4-BMPA;DBCO-PEG4-maleimide;DBCO-NH-PEG4-Maleimide;DBCO-NHCO-PEG4-NH-Maleimide;Dibenzocyclooctyne-PEG4-maleimide;DBCO-PEG4-Maleimide,Dibenzocyclooctyne-PEG4-maleimide;[DBCO-PEG-MAL] α-Dibenzocyclooctyne-ω-maleimide poly(ethylene glycol);1H-Pyrrole-1-propanamide, N-[19-(11,12-dihydrodibenz[b,f]azocin-5(6H)-yl)-15-oxo-3,6,9,12-tetraoxa-16-azanondec-1-yl]-2,5-dihydro-2,5-dioxo-
CBNumber: CB52925269
Molecular Formula: C36H42N4O9
Formula Weight: 674.74
MOL File: 1480516-75-3.mol

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DBCO-PEG4-maleimide Property

Boiling point:: 965.2±65.0 °C(Predicted)
Density: 1.31±0.1 g/cm3(Predicted)
storage temp.: -20°C
solubility: Soluble in DMSO, DCM, DMF
pka: 15.01±0.46(Predicted)
form: Viscous liquid
InChIKey: VVFZXPZWVJMYPX-UHFFFAOYSA-N
SMILES: N1(CCC(NCCOCCOCCOCCOCCC(=O)NCCC(N2CC3=CC=CC=C3C#CC3=CC=CC=C23)=O)=O)C(=O)C=CC1=O

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 760676
Product name: Dibenzocyclooctyne-PEG4-maleimide
Purity: for Copper-free Click Chemistry
Packaging: 1MG
Price: $39.9
Updated: 2023/06/20

Sigma-Aldrich

Product number: 760676
Product name: Dibenzocyclooctyne-PEG4-maleimide
Purity: for Copper-free Click Chemistry
Packaging: 5MG
Price: $134
Updated: 2023/06/20

Sigma-Aldrich

Product number: 760676
Product name: Dibenzocyclooctyne-PEG4-maleimide
Purity: for Copper-free Click Chemistry
Packaging: 50MG
Price: $458
Updated: 2023/06/20

Alfa Aesar

Product number: J65673
Product name: Azadibenzocyclooctyne-PEG4-maleimide
Packaging: 10mg
Price: $148
Updated: 2023/06/20

Alfa Aesar

Product number: J65673
Product name: Azadibenzocyclooctyne-PEG4-maleimide
Packaging: 25mg
Price: $301
Updated: 2023/06/20

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DBCO-PEG4-maleimide Chemical Properties,Usage,Production

Description

DBCO-PEG4-Maleimide is PEG linker containing a maleimide group and a DBCO moiety. The hydrophilic PEG spacer arm improves solubility in aqueous buffers. Maleimide group specifically and efficiently reacts with thiols to form stable thioether bonds. The low mass weight will add minimal spacer to modified molecules and will enable simple and efficient incorporation of DBCO moiety onto cysteine-containing peptides or other thiol-containing biomolecules. DBCO is commonly used for copper-free Click Chemistry reactions.

Uses

Maleimide functionalized cyclooctyne derivative for incorporation of the cyclooctyne moiety into thiol containing compounds or biomolecules. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage. The PEG lipophilic spacer helps to reduce aggregation and precipitation problems when labeling biomolecules.
Applications Include:

Protein-peptide conjugates
Antibody-enzyme or antibody-drug conjugates
Protein or peptide-oligonucleotide conjugates
Surface modification

DBCO-PEG4-maleimide Preparation Products And Raw materials

Raw materials

Preparation Products

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DBCO-PEG4-maleimide Suppliers

China 49 United States 8 Global 57

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 19892
Advantage: 58

BOC Sciences

Tel: +1-631-485-4226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 19553
Advantage: 58

9i LLC

Tel: +18039569191
Fax: +13026429191
Email: MWan@NiNeiLab.com
Country: United States
ProdList: 418
Advantage: 58

Aladdin Scientific

Tel: +1-833-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57511
Advantage: 58

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View Lastest Price from DBCO-PEG4-maleimide manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: DBCO-PEG4-Maleimide 1480516-75-3
Price: US $0.00/mg
Min. Order: 25mg
Purity: >99.00%
Supply Ability: 100
Release date: 2024-03-20

1480516-75-3, DBCO-PEG4-maleimideRelated Search:

DBCO-PEG4-biotin DBCO-PEG4-Benzylamine DBCO-PEG4-Val-Cit-PAB-PNP DBCO-PEG4-DBCO DBCO-PEG4-SE DBCO-PEG4-amine DBCO-maleimide DBCO-PEG4-Acid DBCO-PEG3-amine DBCO-PEG5-CH2CH2COOH DBCO-PEG4-amine BDP FL DBCO DBCO-PEG4-TAMRA DBCO-amine 2-(4-Ethyl-1-piperazinyl)-4-[4-(4-ethyl-1-piperazinyl)phenyl]-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine

DBCO-PEG4-maleimide

Dibenzocyclooctyne-PEG4-maleimide

DBCO-NH-PEG4-Maleimide

DBCO-PEG4-Maleimide,Dibenzocyclooctyne-PEG4-maleimide

1H-Pyrrole-1-propanamide, N-[19-(11,12-dihydrodibenz[b,f]azocin-5(6H)-yl)-15-oxo-3,6,9,12-tetraoxa-16-azanondec-1-yl]-2,5-dihydro-2,5-dioxo-

DBCO-dPEG??-MAL

N-(3-(11,12-dihydrodibenzo[b,f]azocin-5(6H)-yl)propyl)-1-(3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamido)-3,6,9,12-tetraoxapentadecan-15-amide

[DBCO-PEG-MAL] α-Dibenzocyclooctyne-ω-maleimide poly(ethylene glycol)

DBCO-NHCO-PEG4-BMPA

1H-Pyrrole-1-propanamide, N-[19-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-15,19-dioxo-3,6,9,12-tetraoxa-16-azanonadec-1-yl]-2,5-dihydro-2,5-dioxo-

DBCO-NHCO-PEG4-NH-Maleimide

DBCO-PEG4-MAL

1480516-75-3

C36H42N4O9

PROTAC LINKER