ChemicalBook > CAS DataBase List > t-Boc-N-amido-PEG1-NHS ester

t-Boc-N-amido-PEG1-NHS ester

Product Name
t-Boc-N-amido-PEG1-NHS ester
CAS No.
1260092-55-4
Chemical Name
t-Boc-N-amido-PEG1-NHS ester
Synonyms
Boc-N-PEG1-C2-NHS ester;BocNH-PEG1-CH2CH2COONHS;t-Boc-N-amido-PEG1-NHS ester;BocNH-PEG1-CH2CH2COONHS ester;2,5-Dioxopyrrolidin-1-yl 3-(2-((tert-butoxycarbonyl)amino)ethoxy)propanoate;Propanoic acid, 3-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester;BocNH-PEG1-CH2CH2COONHS/Propanoic acid, 3-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester
CBNumber
CB54849668
Molecular Formula
C14H22N2O7
Formula Weight
330.33
MOL File
1260092-55-4.mol
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t-Boc-N-amido-PEG1-NHS ester Property

Density 
1.26±0.1 g/cm3(Predicted)
storage temp. 
Storage temp. -20°C
pka
12.21±0.46(Predicted)
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-23959
Product name
t-Boc-N-amido-PEG1-NHSester
Purity
98%
Packaging
250mg
Price
$380
Updated
2021/12/16
BroadPharm
Product number
BP-23959
Product name
t-Boc-N-amido-PEG1-NHSester
Purity
98%
Packaging
500mg
Price
$580
Updated
2021/12/16
Activate Scientific
Product number
AS107902
Product name
BocNH-PEG1-CH2CH2COONHS
Purity
97%
Packaging
1g
Price
$580
Updated
2021/12/16
BroadPharm
Product number
BP-23959
Product name
t-Boc-N-amido-PEG1-NHSester
Purity
98%
Packaging
1g
Price
$870
Updated
2021/12/16
Ambeed
Product number
A581867
Product name
2,5-Dioxopyrrolidin-1-yl3-(2-((tert-butoxycarbonyl)amino)ethoxy)propanoate
Purity
98%
Packaging
100mg
Price
$52
Updated
2021/12/16
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t-Boc-N-amido-PEG1-NHS ester Chemical Properties,Usage,Production

Description

t-Boc-N-amido-PEG1-NHS ester is a PEG linker containing NHS ester and Boc-protected amine moieties. The hydrophilic PEG spacer increases solubility in aqueous media. The Boc group can be deprotected under mild acidic conditions to form a free amine. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

Uses

Boc-N-PEG1-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

t-Boc-N-amido-PEG1-NHS ester Preparation Products And Raw materials

Raw materials

Preparation Products

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t-Boc-N-amido-PEG1-NHS ester Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354;
Email
support@targetmol.com
Country
United States
ProdList
39035
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
52923
Advantage
58
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
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View Lastest Price from t-Boc-N-amido-PEG1-NHS ester manufacturers

LAURENT
Product
BocNH-PEG1-CH2CH2COONHS ester 1260092-55-4
Price
US $507.00/g
Min. Order
1g
Purity
98%
Supply Ability
300kg
Release date
2025-11-22
Xian confluore Biological Technology Co., Ltd.
Product
t-Boc-N-amido-PEG1-NHS ester 1260092-55-4
Price
US $0.00/g
Min. Order
5g
Purity
>98.00%
Supply Ability
5g
Release date
2024-03-25

1260092-55-4, t-Boc-N-amido-PEG1-NHS esterRelated Search:


  • t-Boc-N-amido-PEG1-NHS ester
  • BocNH-PEG1-CH2CH2COONHS
  • Boc-N-PEG1-C2-NHS ester
  • 2,5-Dioxopyrrolidin-1-yl 3-(2-((tert-butoxycarbonyl)amino)ethoxy)propanoate
  • BocNH-PEG1-CH2CH2COONHS/Propanoic acid, 3-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester
  • Propanoic acid, 3-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester
  • BocNH-PEG1-CH2CH2COONHS ester
  • 1260092-55-4