Dansyl chloride
Uses- Product Name
- Dansyl chloride
- CAS No.
- 605-65-2
- Chemical Name
- Dansyl chloride
- Synonyms
- DNS;dansyl;DNSCL;5-DIMETHYLAMINO-1-NAPHTHALENESULFONYL CHLORIDE;SKL100;AI301174;AI3 01174;AI3-01174;DNS chloride;ansylchloride
- CBNumber
- CB5696240
- Molecular Formula
- C12H12ClNO2S
- Formula Weight
- 269.75
- MOL File
- 605-65-2.mol
Dansyl chloride Property
- Melting point:
- 72-74 °C(lit.)
- Boiling point:
- 371.3±22.0 °C(Predicted)
- Density
- 1.1702 (rough estimate)
- refractive index
- 1.5630 (estimate)
- storage temp.
- 2-8°C
- solubility
- acetone: 50 mg/mL
- form
- powder and chunks
- pka
- 2.38±0.40(Predicted)
- color
- yellow to orange
- Water Solubility
- Soluble in dimethyl fluoride, acetone, chloroform, pyridine, benzene and dioxane. Insoluble in water.
- Sensitive
- Moisture Sensitive
- Merck
- 14,2814
- BRN
- 2217205
- Stability:
- Hygroscopic, Moisture Sensitive
- InChIKey
- XPDXVDYUQZHFPV-UHFFFAOYSA-N
- CAS DataBase Reference
- 605-65-2(CAS DataBase Reference)
- EPA Substance Registry System
- 1-Naphthalenesulfonyl chloride, 5-(dimethylamino)- (605-65-2)
Safety
- Hazard Codes
- C
- Risk Statements
- 34
- Safety Statements
- 26-36/37/39-45-3
- RIDADR
- UN 3261 8/PG 2
- WGK Germany
- 3
- RTECS
- QK3688000
- F
- 10-21
- TSCA
- Yes
- HazardClass
- 8
- PackingGroup
- III
- HS Code
- 29214980
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H290May be corrosive to metals
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
N-Bromosuccinimide Price
- Product number
- 39220
- Product name
- Dansyl chloride
- Purity
- BioReagent, suitable for fluorescence, ≥99.0% (HPLC)
- Packaging
- 1g
- Price
- $119
- Updated
- 2024/03/01
- Product number
- 39220
- Product name
- Dansyl chloride
- Purity
- BioReagent, suitable for fluorescence, ≥99.0% (HPLC)
- Packaging
- 5G
- Price
- $481
- Updated
- 2024/03/01
- Product number
- 39220
- Product name
- Dansyl chloride
- Purity
- BioReagent, suitable for fluorescence, ≥99.0% (HPLC)
- Packaging
- 50g
- Price
- $2450
- Updated
- 2024/03/01
- Product number
- 03641
- Product name
- Dansyl chloride
- Purity
- for HPLC derivatization, ≥99.0% (HPLC)
- Packaging
- 100mg
- Price
- $47.3
- Updated
- 2024/03/01
- Product number
- 311155
- Product name
- Dansyl Chloride - CAS 605-65-2 - Calbiochem
- Purity
- Reagent used for fluorescent labeling of proteins, N-terminal amino acids, and amines.
- Packaging
- 1G
- Price
- $77.6
- Updated
- 2024/03/01
Dansyl chloride Chemical Properties,Usage,Production
Uses
Dansyl chloride or 5-Dimethylaminonaphthalene-1-sulfonyl chloride (CAS 605-65-2) is a fluorogenic reagent used for protein, N-terminal amino acid and peptide detection by reverse phase high performance liquid chromatography (HPLC). It is also used to determine the degree of labeling in chymotrypsin and ovalbumin. It acts as a precursor for the synthesis of other derivatives like dansyl amide.
Dansyl chloride is non-fluorescent until it reacts with amines. The resulting Dansyl amides have environmentally sensitive fluorescence quantum yields and emission maxima along with large Stokes shifts. This environment-sensitive fluorescence property has made Dansyl chloride an important tool for biophysical studies.
Chemical Properties
yellow to orange-yellow crystalline powder
Uses
A fluorogenic reagent for N-terminal derivatization of amino acids and peptides and detection by reverse phase HPLC.
Uses
Dansyl chloride is a fluorogenic reagent used for protein, N-terminal amino acid and peptide detection by reverse phase high performance liquid chromatography (HPLC). It is also used to determine the degree of labeling in chymotrypsin and ovalbumin. It acts as a precursor for the synthesis of other derivatives like dansyl amide.
Uses
Reagent for fluorescent labelling of amines, amino acids and proteins.
Uses
In fluorescent labelling, column chromatography, HPLC.
Definition
ChEBI: Dansyl chloride is an aminonaphthalene and a sulfonic acid derivative.
General Description
Dansyl chloride is a fluorogenic reagent which is typically employed for the derivatization of amino acids.
Biochem/physiol Actions
Dansyl chloride is a sulfonyl chloride compound. It is used to end tag amino groups of peptides and proteins. Dansyl chloride is used for derivatization of free amino acids and amines in neural samples and biological fluids. It is used to study fluorescent conjugates of albumin, protein conformational changes studies and active site characterization.
Safety Profile
Poison by intravenous route, When heated to decomposition it emits very toxic fumes of Cland NOx
Dansyl chloride Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Dansyl chloride manufacturers
- Product
- 5-(Dimethylamino)naphthalene-1-sulfonyl chloride 605-65-2
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98.8%
- Supply Ability
- 100 tons
- Release date
- 2022-02-21
- Product
- Dansyl chloride 605-65-2
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 200kg
- Release date
- 2018-12-25