tasquinimod

Product Name: tasquinimod
CAS No.: 254964-60-8
Chemical Name: tasquinimod
Synonyms: TASQ);ABR-215050;tasquinimod;Tasquinimod, >98%;Tasquinimod(ABR-215050);7-diMethoxy-4-quinolinyl)oxy]-;ABR-215050; ABR215050; ABR 215050;7-Dimethoxy-quinolin-4-yloxy)-phenylamine;4-hydroxy-5-methoxy-N,1-dimethyl-2-oxo-N-[4-(trifluoromethyl)phenyl]quinoline-3-carboxamide;4-Hydroxy-5-methoxy-N,1-dimethyl-2-oxo-N-(4-(trifluoromethyl)-phenyl)-1,2-dihydroquinoline-3-c
CBNumber: CB61508619
Molecular Formula: C20H17F3N2O4
Formula Weight: 406.36
MOL File: 254964-60-8.mol

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tasquinimod Property

Boiling point:: 501.5±50.0 °C(Predicted)
Density: 1.427±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: insoluble in H2O; ≥20.32 mg/mL in DMSO; ≥4.75 mg/mL in EtOH with gentle warming and ultrasonic
form: solid
pka: 4.50±1.00(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 17692
Product name: Tasquinimod
Purity: ≥98%
Packaging: 1mg
Price: $49
Updated: 2024/03/01

Cayman Chemical

Product number: 17692
Product name: Tasquinimod
Purity: ≥98%
Packaging: 5mg
Price: $202
Updated: 2024/03/01

Cayman Chemical

Product number: 17692
Product name: Tasquinimod
Purity: ≥98%
Packaging: 10mg
Price: $356
Updated: 2024/03/01

Cayman Chemical

Product number: 17692
Product name: Tasquinimod
Purity: ≥98%
Packaging: 25mg
Price: $593
Updated: 2024/03/01

Tocris

Product number: 7051
Product name: Tasquinimod
Purity: ≥98%(HPLC)
Packaging: 25
Price: $295
Updated: 2021/12/16

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tasquinimod Chemical Properties,Usage,Production

Description

Tasquinimod is an orally-active quinoline-3-carboxamide derived from roquinimex, an immunomodulatory quinolone with applications in some cancers and autoimmune diseases. Tasquinimod inhibits tumor angiogenesis and supplements radiation or chemotherapy in animal models of prostate cancer. While its precise mechanism of action remains unclear, tasquinimod has been reported to alter signaling through S100A9, thrombospondin-1, HIF-1α, androgen receptor, VEGF, and HDAC3/4.

Uses

Tasquinimod is an orally active antiangiogenic agent which may inhibit HDAC4 signalling. This affects cancer cell survival thus making this compound and anti-cancer agent.

target

tumor microenvironment

storage

Store at -20°C

tasquinimod Preparation Products And Raw materials

Raw materials

Preparation Products

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tasquinimod Suppliers

China 89 India 2 United States 12 Global 103

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View Lastest Price from tasquinimod manufacturers

Career Henan Chemical Co

Product: tasquinimod 254964-60-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98-100%
Supply Ability: 1000kg
Release date: 2018-08-20

254964-60-8, tasquinimodRelated Search:

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4-Hydroxy-5-methoxy-N-methyl-1-methyl-2-oxo-N-(4-trifluoromethylphenyl)-1,2-dihydroquinoline-3-carboxamide

N-Methyl-N-(4-trifluoromethylphenyl)-1,2-dihydro-4-hydroxy-5-methoxy-1-methyl-2-oxoquinoline-3-carboxamide

tasquinimod

ABR-215050

3-QuinolinecarboxaMide, 1,2-dihydro-4-hydroxy-5-Methoxy-N,1-diMethyl-2-oxo-N-[4-(trifluoroMethyl)phenyl]-

4-Hydroxy-5-Methoxy-1-Methyl-2-oxo-1,2- dihydro-quinoline-3-carboxylic acid Methyl- (4-trifluoroMethyl-phenyl)-aMide

1,2-dihydro-4-hydroxy-5-methoxy-N,1-dimethyl-2-oxo-N-[4-trifluoromethyl)phenyl]-3-quinolinecarboxamide

4-Hydroxy-5-methoxy-N,1-dimethyl-2-oxo-N-(4-(trifluoromethyl)-phenyl)-1,2-dihydroquinoline-3-c

4-Hydroxy-N-[4-(trifluoromethyl)phenyl]-5-methoxy-N,1-dimethyl-2-oxo-1,2-dihydroquinoline-3-carboxamide

ABR-215050; ABR215050; ABR 215050

Tasquinimod, >98%

Tasquinimod(ABR-215050)

TASQ)

7-diMethoxy-4-quinolinyl)oxy]-

7-Dimethoxy-quinolin-4-yloxy)-phenylamine

4-Hydroxy-5-methoxy-N,1-dimethyl-2-oxo-N-(4-(trifluoromethyl)phenyl)-1,2-dihydroquinoline-3-carboxamide

4-hydroxy-5-methoxy-N,1-dimethyl-2-oxo-N-[4-(trifluoromethyl)phenyl]quinoline-3-carboxamide

254964-60-8

Angiogenesis inhibitor

S100 calcium binding protein A9 modulator

Inhibitors