3-Chloroisonicotinic acid
- Product Name
- 3-Chloroisonicotinic acid
- CAS No.
- 88912-27-0
- Chemical Name
- 3-Chloroisonicotinic acid
- Synonyms
- 3-CHLOROISONICOTINIC ACID;3- chlorineisonicotinic acid;3-Chloroisonicotinic Acid >3-Chloro-4-pyridine carboxlic acid;3-CHLORO-4-PYRIDINECARBOXYLIC ACID;3-CHLOROPYRIDINE-4-CARBOXYLIC ACID;3-Chloropyridin-4-ylcarboxylic acid;4-Pyridinecarboxylic acid, 3-chloro-;3-Chloropyridine-4-carboxylic acid 97%;3-Chloropyridine-4-carboxylic Acid, 97+%
- CBNumber
- CB6249797
- Molecular Formula
- C6H4ClNO2
- Formula Weight
- 157.55
- MOL File
- 88912-27-0.mol
3-Chloroisonicotinic acid Property
- Melting point:
- 227-231 °C (dec.)(lit.)
- Boiling point:
- 387.0±22.0 °C(Predicted)
- Density
- 1.470±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- pka
- 0.12±0.25(Predicted)
- form
- Solution
- color
- Brown to dark green to black
- InChIKey
- MYAZXWFEMDJTFE-UHFFFAOYSA-N
- CAS DataBase Reference
- 88912-27-0(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H319Causes serious eye irritation
- Precautionary statements
-
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 633410
- Product name
- 3-Chloropyridine-4-carboxylic acid
- Purity
- 97%
- Packaging
- 1g
- Price
- $31.7
- Updated
- 2023/06/20
- Product number
- 633410
- Product name
- 3-Chloropyridine-4-carboxylic acid
- Purity
- 97%
- Packaging
- 5g
- Price
- $38.4
- Updated
- 2023/06/20
- Product number
- C2983
- Product name
- 3-Chloroisonicotinic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $78
- Updated
- 2025/07/31
- Product number
- C2983
- Product name
- 3-Chloroisonicotinic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $308
- Updated
- 2025/07/31
- Product number
- C367378
- Product name
- 3-Chloroisonicotinic Acid
- Packaging
- 5g
- Price
- $75
- Updated
- 2021/12/16
3-Chloroisonicotinic acid Chemical Properties,Usage,Production
Synthesis
626-60-8
88912-27-0
A. Synthesis of 3-chloro-N-(4-chlorophenyl)pyridine-4-carboxamide. At -78 °C, 3-chloropyridine (1.00 mL, 10.5 mmol) was dissolved in THF and a freshly prepared lithium diisopropylammonium THF solution [prepared by the reaction of butyl lithium (7.21 mL, 11.5 mmol) with diisopropylamine (11.5 mmol)] was slowly added. After 0.25 h of reaction, carbon dioxide gas was passed into the mixture and slowly warmed to room temperature. After completion of the reaction, the mixture was concentrated and subsequently partitioned between EtOAc and water. The aqueous layer was washed twice with EtOAc. The pH of the aqueous layer was adjusted to about 3 by adding 1N HCl and extracted three more times with EtOAc. The organic phases were combined, dried with magnesium sulfate and concentrated. The residue was recrystallized by EtOAc to give 200 mg (12% yield) of 3-chloroisonicotinic acid.
References
[1] Patent: US6610704, 2003, B1
3-Chloroisonicotinic acid Preparation Products And Raw materials
Raw materials
Preparation Products
3-Chloroisonicotinic acid Suppliers
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View Lastest Price from 3-Chloroisonicotinic acid manufacturers
- Product
- 3-Chloroisonicotinic acid 88912-27-0
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-10-25
- Product
- 3-Chloroisonicotinic acid 88912-27-0
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- Customized
- Release date
- 2018-12-14