ChemicalBook > CAS DataBase List > 7Methyl-5-(1-{[3-(trifluoroMethyl)phenyl]acetyl}-2,3-dihydro1Hindol-5-yl)7Hpyrrolo[2,3d]pyriMidin-4-aMine

7Methyl-5-(1-{[3-(trifluoroMethyl)phenyl]acetyl}-2,3-dihydro1Hindol-5-yl)7Hpyrrolo[2,3d]pyriMidin-4-aMine

Product Name
7Methyl-5-(1-{[3-(trifluoroMethyl)phenyl]acetyl}-2,3-dihydro1Hindol-5-yl)7Hpyrrolo[2,3d]pyriMidin-4-aMine
CAS No.
1337531-36-8
Chemical Name
7Methyl-5-(1-{[3-(trifluoroMethyl)phenyl]acetyl}-2,3-dihydro1Hindol-5-yl)7Hpyrrolo[2,3d]pyriMidin-4-aMine
Synonyms
GSK2606414;CS-868;NSC231323;NSC 231323;NSC-231323;Lactosit Miruhen;GSK2606414, >=98%;GSK2606414;GSK-2606414;GSK2606414 (Free base);PERK inhibitor GS2606414
CBNumber
CB62616980
Molecular Formula
C24H20F3N5O
Formula Weight
451.44
MOL File
1337531-36-8.mol
More
Less

7Methyl-5-(1-{[3-(trifluoroMethyl)phenyl]acetyl}-2,3-dihydro1Hindol-5-yl)7Hpyrrolo[2,3d]pyriMidin-4-aMine Property

Melting point:
176 - 180°C
Boiling point:
720.3±60.0 °C(Predicted)
Density 
1.43±0.1 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
5.76±0.30(Predicted)
form 
Solid
color 
Off-White to Pale Yellow
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
17376
Product name
GSK2606414
Purity
≥98%
Packaging
1mg
Price
$36
Updated
2024/03/01
Cayman Chemical
Product number
17376
Product name
GSK2606414
Purity
≥98%
Packaging
5mg
Price
$155
Updated
2024/03/01
Cayman Chemical
Product number
17376
Product name
GSK2606414
Purity
≥98%
Packaging
10mg
Price
$274
Updated
2024/03/01
Cayman Chemical
Product number
17376
Product name
GSK2606414
Purity
≥98%
Packaging
50mg
Price
$834
Updated
2024/03/01
Tocris
Product number
5107
Product name
GSK2606414
Purity
≥99%(HPLC)
Packaging
50
Price
$1179
Updated
2021/12/16
More
Less

7Methyl-5-(1-{[3-(trifluoroMethyl)phenyl]acetyl}-2,3-dihydro1Hindol-5-yl)7Hpyrrolo[2,3d]pyriMidin-4-aMine Chemical Properties,Usage,Production

Uses

GSK 2606414 acts as a potent and selective inhibitor of protein kinase R and similarly endoplasmic reticulum kinase affecting numerous diseases such as cancer.

storage

Store at -20°C

7Methyl-5-(1-{[3-(trifluoroMethyl)phenyl]acetyl}-2,3-dihydro1Hindol-5-yl)7Hpyrrolo[2,3d]pyriMidin-4-aMine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

7Methyl-5-(1-{[3-(trifluoroMethyl)phenyl]acetyl}-2,3-dihydro1Hindol-5-yl)7Hpyrrolo[2,3d]pyriMidin-4-aMine Suppliers

China 107 India 1 United Kingdom 2 United States 18 Global 128
Novachemistry
Tel
44-20819178-90 02081917890
Fax
(0)2080432064
Email
info@novachemistry.com
Country
United Kingdom
ProdList
4381
Advantage
58
Tocris Bioscience
Tel
--
Fax
--
Email
customerservice@tocris.co.uk
Country
United Kingdom
ProdList
5726
Advantage
77

1337531-36-8, 7Methyl-5-(1-{[3-(trifluoroMethyl)phenyl]acetyl}-2,3-dihydro1Hindol-5-yl)7Hpyrrolo[2,3d]pyriMidin-4-aMineRelated Search:

GSK-2126458 GSK1292263 GSK-25 S)-1-(sec-butyl)-N-((4,6-diMethyl-2-oxo-1,2-dihydropyridin-3-yl)Methyl)-3-Methyl-6-(6-(piperazin-1-yl)pyridin-3-yl)-1H-indole-4-carboxaMide GSK 2801 GSK2636771 GSK2879552 GSK2795039 GSK 2330672 GSK2838232 MKC8866 MKC3946 ISRIB SB216763 GSK2656157 SALUBRINAL MG-132 7-hydroxy-4-Methyl-2-oxo-2H-1-Benzopyran-8-carboxaldehyde

  • 7-Methyl-5-[1-[[3-(trifluoromethyl)phenyl]acetyl]-2,3-dihydro-1H-indol-5-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine GSK2606414
  • GSK2606414/ 7Methyl-5-(1-{[3-(trifluoroMethyl)phenyl]acetyl}-2,3-dihydro1Hindol-5-yl)7Hpyrrolo[2,3d]pyriMidin-4-aMine
  • GSK2606414, >=98%
  • GSK2606414 (Free base)
  • GSK2606414;GSK 2606414;GSK-2606414
  • 1-(5-(4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-indolin-1-yl)-2-(3-(trifluoromethyl)ph
  • 7Methyl-5-(1-{[3-(trifluoroMethyl)phenyl]acetyl}-2,3-dihydro1Hindol-5-yl)7Hpyrrolo[2,3d]pyriMidin-4-aMine
  • GSK2606414
  • 1-(5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)indolin-1-yl)-2-(3-(trifluoromethyl)phenyl)ethanone
  • GSK2606414;GSK-2606414
  • 1-[5-(4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2,3-dihydro-1H-indol-1-yl]-2-[3-(trifluoromethyl)phenyl]ethanone
  • PERK inhibitor GS2606414
  • CS-868
  • Ethanone, 1-[5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydro-1H-indol-1-yl]-2-[3-(trifluoromethyl)phenyl]-
  • 7Methyl-5-(1-{[3-(trifluoroMethyl)phenyl]acetyl}-2,3-dihydro1Hindol-5-yl)7Hpyrrolo[2,3d]pyriMidin-4-aMine USP/EP/BP
  • GSK2606414,acell-permeableandorallyavailablePERKinhibitor
  • Lactosit Miruhen
  • NSC 231323
  • NSC231323
  • NSC-231323
  • 1337531-36-8
  • C24H20F3N5O
  • Inhibitors