ChemicalBook > CAS DataBase List > VU0238441

VU0238441

Product Name
VU0238441
CAS No.
85511-68-8
Chemical Name
VU0238441
Synonyms
VU0238441;VU0238441, 10 mM in DMSO;7-Chloro-1-(4-(trifluoromethyl)benzyl)indoline-2,3-dione;7-chloro-1-[[4-(trifluoromethyl)phenyl]methyl]indole-2,3-dione;7-Chloro-1-[[4-(trifluoromethyl)phenyl]methyl]-1H-indole-2,3-dione;1H-Indole-2,3-dione, 7-chloro-1-[[4-(trifluoroMethyl)phenyl]Methyl]-;mAChR,Inhibitor,VU-0238441,VU0238441,Muscarinic acetylcholine receptor,VU 0238441,inhibit
CBNumber
CB62628523
Molecular Formula
C16H9ClF3NO2
Formula Weight
339.7
MOL File
85511-68-8.mol
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VU0238441 Property

Boiling point:
441.7±55.0 °C(Predicted)
Density 
1.500±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO: 125 mg/mL (367.97 mM)
pka
-3?+-.0.20(Predicted)
form 
Solid
color 
Brown to red
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0003123
Product name
VU0238441
Purity
≥97.0%
Packaging
5mg
Price
$50
Updated
2021/12/16
ChemScene
Product number
CS-0003123
Product name
VU0238441
Purity
≥97.0%
Packaging
10mg
Price
$70
Updated
2021/12/16
ChemScene
Product number
CS-0003123
Product name
VU0238441
Purity
≥97.0%
Packaging
25mg
Price
$130
Updated
2021/12/16
ChemScene
Product number
CS-0003123
Product name
VU0238441
Purity
≥97.0%
Packaging
50mg
Price
$180
Updated
2021/12/16
ChemScene
Product number
CS-0003123
Product name
VU0238441
Purity
≥97.0%
Packaging
100mg
Price
$250
Updated
2021/12/16
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VU0238441 Chemical Properties,Usage,Production

Biological Activity

VU0238441 is a positive allosteric modulator (PAM) of pan-muscarinic acetylcholine receptor (mAChR) with EC50 values of 2.1 μM, 2.2 μM, 2.8 μM, 3.2 μM and > 2.1 μM, 2.2 μM, 2.8 μM, 3.2 μM and > for M5, M3, M2, M1 and M4, respectively 10 μM.

in vitro

VU0238441 is an analogue of VU0119498.

target

< td style="border-bottom: 1px dotted #ccc;padding: 5px;"> 2.1 μM
TargetValue
mAChR M5
(Cell-free assay)
mAChR M3
(Cell-free assay)		 2.2 μM
mAChR M2
(Cell-free assay)		 2.8 μM
mAChR M1
(Cell-free assay)		 3.2 μM
mAChR M4
(Cell-free assay)		 >10 μM

VU0238441 Preparation Products And Raw materials

Raw materials

Preparation Products

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VU0238441 Suppliers

China 30 United States 5 Global 35
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696，15000506266 15000506266
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+86-21-52996696
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China
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Tianjin Kailiqi Biotechnology Co., Ltd.
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15076683720
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022-23754520
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klq@cw-bio.com
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China
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6021
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55
ShangHai Biochempartner Co.,Ltd
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17754423994 17754423994
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QQ:2853530913
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2853530910@QQ.com
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Shanghai SuperLan Chemcial Technique Centre
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021-2022843681 15618226720
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+86-21-51601218
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lucy@atkchemical.com
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China
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Twochem Co.Ltd.
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021-58111628 15800915896
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QQ 3285589261
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sales@twochem.com
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Zhejiang J&C Biological Technology Co.,Limited
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+1-2135480471 +1-2135480471
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sales@sarms4muscle.com
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DC Chemicals
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021-58447131 13564518121
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sales@dcchemicals.com
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0519-85788828 13775037613
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sales@chemrenpharm.com
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cjbscvictory
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13348960310 13348960310
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3003867561@qq.com
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Abmole Bioscience Inc.
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021-50967598 02150967598
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sales@abmole.cn
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Jinan Jiuli Biotechnology Co. , Ltd.
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15865264761
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486064515@qq.com
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Beijing Jin Ming Biotechnology Co., Ltd.
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010-60605840 15801484223;
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psaitong@jm-bio.com
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Hefei Mokai Pharmaceutical Technology Co., Ltd
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Bide Pharmatech Ltd.
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product02@bidepharm.com
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InvivoChem
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sales@invivochem.cn
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TargetMol Chemicals Inc.
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4008200310
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marketing@tsbiochem.com
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Henan Alpha Chemical Co., Ltd.
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2853979810@qq.com
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Nanjing Tengyi Biotechnology Co., Ltd
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025-58851786 17714337195
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sales@tybiochem.com
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Shanghai Jieshikai Biotechnology Co. , Ltd.
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021-57520305 15801958784
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lihua@jskchem.com
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Nanjing Shizhou Biology Technology Co.,Ltd
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Shanghai Aladdin Biochemical Technology Co.,Ltd.
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Tianjin Rongshen Chemical Co., Ltd
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Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd.
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025-66061636 18013972705
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Shanghai Hansi Chemical Industry Co., Ltd.
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Shaoguan Qicheng Biotechnology Co., Ltd
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Sangon Biotech (Shanghai) Co.,Ltd.
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ATK CHEMICAL COMPANY LIMITED
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Biorbyt Ltd.
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Absin Bioscience Inc.
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Proteintech China
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85511-68-8, VU0238441Related Search:

VU0134992(hydrochloride) VU6012962 VU0810464 VU6015929 N-(4-Chloro-3-methoxyphenyl)-2-pyridinecarboxamide 1-(4-Methoxybenzyl)-5-trifluoromethoxyisatin VUN65671 VU 0357121 VU6010608 VU 0364439 VU-29 2-[2-bromo-4-(propan-2-yl)phenoxy]-N-(2,2,6,6-tetramethylpiperidin-4-yl)acetamide VUF 10460 VUF 10166 N6022 VU 0364770 VU 0357017 hydrochloride 1-(4-BROMOBENZYL)INDOLE-2,3-DIONE

  • VU0238441
  • 1H-Indole-2,3-dione, 7-chloro-1-[[4-(trifluoroMethyl)phenyl]Methyl]-
  • 7-chloro-1-[[4-(trifluoromethyl)phenyl]methyl]indole-2,3-dione
  • 7-Chloro-1-[[4-(trifluoromethyl)phenyl]methyl]-1H-indole-2,3-dione
  • 7-Chloro-1-(4-(trifluoromethyl)benzyl)indoline-2,3-dione
  • mAChR,Inhibitor,VU-0238441,VU0238441,Muscarinic acetylcholine receptor,VU 0238441,inhibit
  • VU0238441, 10 mM in DMSO
  • 85511-68-8