4-Fluorobenzaldehyde
- Product Name
- 4-Fluorobenzaldehyde
- CAS No.
- 459-57-4
- Chemical Name
- 4-Fluorobenzaldehyde
- Synonyms
- PFBA;P-FLUOROBENZALDEHYDE;PFAD;Benzaldehyde, 4-fluoro-;NSC 68095;JACS-459-57-4;AKOS BBS-00003166;4-Fluorbenzaldehyd;P-FLUORBENZALDEHYDE;p-Fluoro benzaldehy
- CBNumber
- CB6299747
- Molecular Formula
- C7H5FO
- Formula Weight
- 124.11
- MOL File
- 459-57-4.mol
4-Fluorobenzaldehyde Property
- Melting point:
- -10 °C (lit.)
- Boiling point:
- 181 °C/758 mmHg (lit.)
- Density
- 1.157 g/mL at 25 °C (lit.)
- vapor pressure
- 19 hPa (70 °C)
- refractive index
- n20/D 1.521(lit.)
- Flash point:
- 134 °F
- storage temp.
- Store below +30°C.
- solubility
- Chloroform, Methanol
- form
- Liquid
- color
- Clear colorless to yellow
- Specific Gravity
- 1.157
- Water Solubility
- IMMISCIBLE
- Sensitive
- Air Sensitive
- BRN
- 385857
- Stability:
- Air Sensitive
- InChIKey
- UOQXIWFBQSVDPP-UHFFFAOYSA-N
- CAS DataBase Reference
- 459-57-4(CAS DataBase Reference)
- NIST Chemistry Reference
- Benzaldehyde, 4-fluoro-(459-57-4)
- EPA Substance Registry System
- Benzaldehyde, 4-fluoro- (459-57-4)
Safety
- Hazard Codes
- Xi,F
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-37/39-36/37/39-27
- RIDADR
- UN 1989 3/PG 3
- WGK Germany
- 2
- F
- 9-23
- Hazard Note
- Flammable
- TSCA
- T
- HazardClass
- 3.2
- PackingGroup
- III
- HS Code
- 29130000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H226Flammable liquid and vapour
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 128376
- Product name
- 4-Fluorobenzaldehyde
- Purity
- 98%
- Packaging
- 10g
- Price
- $29.4
- Updated
- 2024/03/01
- Product number
- 128376
- Product name
- 4-Fluorobenzaldehyde
- Purity
- 98%
- Packaging
- 50g
- Price
- $76.9
- Updated
- 2024/03/01
- Product number
- 8.18537
- Product name
- 4-Fluorobenzaldehyde
- Purity
- for synthesis
- Packaging
- 25mL
- Price
- $51.5
- Updated
- 2023/01/07
- Product number
- F0191
- Product name
- 4-Fluorobenzaldehyde
- Purity
- >98.0%(GC)
- Packaging
- 25mL
- Price
- $32
- Updated
- 2024/03/01
- Product number
- F0191
- Product name
- 4-Fluorobenzaldehyde
- Purity
- >98.0%(GC)
- Packaging
- 250mL
- Price
- $183
- Updated
- 2024/03/01
4-Fluorobenzaldehyde Chemical Properties,Usage,Production
Chemical Properties
Clear colorless to yellow liquid
Uses
Usually used in the preparation of pyrazolopyridine UR-13756.
Uses
4-Fluorobenzaldehyde is used in the preparation of pyrazolopyridine derivative, which finds application as mitogen-activated protein kinase (MAPK) inhibitor. It also serves as a synthetic intermediate in the preparation of pharmaceutical compounds.
Uses
4-Fluorobenzaldehyde is a fluorinated benzaldehyde with inhibitory activity of mushroom tyrosinase. 4-Fluorobenzaldehyde is commonly used as a synthetic intermediate in the preparation of pharmaceutic al compounds.
Synthesis
4-Fluorobenzaldehyde is produced by a commercially feasible process. The process comprises heating a mixture of fluorobenzene and a strong Lewis acid with dissolved hydrogen halide in an atmosphere of carbon monoxide at about 45 to about 100° C. and at a total pressure of about 150 psig up to the maximum pressure rating of the reactor. Formed is a reaction mass containing a Lewis acid complex of 4-fluorobenzaldehyde and at least a halobis(fluorophenyl)methane by-product. The complex is broken by quenching the reaction mass with a Lewis acid-solvating liquid to liberate 4-fluorobenzaldehyde. By-product halobis(fluorophenyl)methane is converted to di(fluorophenyl)methanol to avoid potential corrosion problems and formation of light-sensitive color bodies in the recovered 4-fluorobenzaldehyde.
4-Fluorobenzaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
4-Fluorobenzaldehyde Suppliers
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- Switzerland
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View Lastest Price from 4-Fluorobenzaldehyde manufacturers
- Product
- 4-Fluorobenzaldehyde 459-57-4
- Price
- US $70.00-25.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2024-06-05
- Product
- 4-Fluorobenzaldehyde 459-57-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-10-28
- Product
- 4-Fluorobenzaldehyde 459-57-4
- Price
- US $10.50/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 10 ton
- Release date
- 2024-08-21