Azadibenzocyclooctyne-Biotin conjugate
- Product Name
- Azadibenzocyclooctyne-Biotin conjugate
- CAS No.
- 1418217-95-4
- Chemical Name
- Azadibenzocyclooctyne-Biotin conjugate
- Synonyms
- DBCO-Biotin;DBCO-(CH2)2-NH2-BIOTIN;Azadibenzocyclooctyne-Biotin conjugate;DBCO-Biotin,Azadibenzocyclooctyne-Biotin conjugate;(3AS,4S,6aR)-N-[3-(11,12-Didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide;1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]hexahydro-2-oxo-, (3aS,4S,6aR)-
- CBNumber
- CB63309380
- Molecular Formula
- C28H30N4O3S
- Formula Weight
- 502.63
- MOL File
- 1418217-95-4.mol
Azadibenzocyclooctyne-Biotin conjugate Property
- Boiling point:
- 905.9±65.0 °C(Predicted)
- Density
- 1.35±0.1 g/cm3(Predicted)
- storage temp.
- -20°C, protect from light, stored under nitrogen
- form
- Solid
- pka
- 13.90±0.40(Predicted)
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- LS-4270
- Product name
- Biotin-DBCO
- Packaging
- 100mg
- Price
- $810
- Updated
- 2021/12/16
- Product number
- LS-4270
- Product name
- Biotin-DBCO
- Packaging
- 250mg
- Price
- $1620
- Updated
- 2021/12/16
- Product number
- DC21887
- Product name
- DBCO-Biotin
- Purity
- >98%
- Packaging
- 250mg
- Price
- $1700
- Updated
- 2021/12/16
- Product number
- DC21887
- Product name
- DBCO-Biotin
- Purity
- >98%
- Packaging
- 1g
- Price
- $3400
- Updated
- 2021/12/16
- Product number
- 288702
- Product name
- DBCO-Biotin
- Purity
- min.95%
- Packaging
- 100mg
- Price
- $650
- Updated
- 2021/12/16
Azadibenzocyclooctyne-Biotin conjugate Chemical Properties,Usage,Production
Uses
DBCO-Biotin is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
IC 50
Alkyl-Chain
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Azadibenzocyclooctyne-Biotin conjugate Preparation Products And Raw materials
Raw materials
Preparation Products
Azadibenzocyclooctyne-Biotin conjugate Suppliers
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View Lastest Price from Azadibenzocyclooctyne-Biotin conjugate manufacturers
- Product
- DBCO-Biotin 1418217-95-4
- Price
- US $0.00/mg
- Min. Order
- 25mg
- Purity
- >99.00%
- Supply Ability
- 100
- Release date
- 2024-03-20