ChemicalBook > CAS DataBase List > Pyrazole

Pyrazole

Product Name
Pyrazole
CAS No.
288-13-1
Chemical Name
Pyrazole
Synonyms
1H-PYRAZOLE;PYRAZOL;1H-Pyrazol;Pyrrazole;Pyrazole, pure, 98%;PYRAZOLE;Ryrazole;1,2-DIAZOL;1,2-DIAZOLE;Pyrazole>
CBNumber
CB6689669
Molecular Formula
C3H4N2
Formula Weight
68.08
MOL File
288-13-1.mol
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Pyrazole Property

Melting point:
67-70 °C (lit.)
Boiling point:
186-188 °C (lit.)
Density 
1.4088 (rough estimate)
vapor pressure 
21Pa at 20℃
refractive index 
1.4203
Flash point:
186-188°C
storage temp. 
Store below +30°C.
solubility 
Chloroform, Methanol
form 
Crystals or Crystalline Powder
pka
2.49(at 25℃)
color 
White to yellow
Water Solubility 
SOLUBLE
Sensitive 
Hygroscopic
Merck 
14,7960
BRN 
103775
InChIKey
WTKZEGDFNFYCGP-UHFFFAOYSA-N
LogP
0.33 at 25℃
CAS DataBase Reference
288-13-1(CAS DataBase Reference)
NIST Chemistry Reference
1H-Pyrazole(288-13-1)
EPA Substance Registry System
Pyrazole (288-13-1)
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38-52-20/21/22
Safety Statements 
26-36/37-61-37/39-36
RIDADR 
2811
WGK Germany 
1
RTECS 
UQ4900000
TSCA 
Yes
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
29331990
Toxicity
LD50 (24 hr) in rats, mice (mmol/kg): 19, 21 i.v.; 21, 22 orally (Magnussen)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H311Toxic in contact with skin

H315Causes skin irritation

H318Causes serious eye damage

H373May cause damage to organs through prolonged or repeated exposure

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P314Get medical advice/attention if you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
P56607
Product name
Pyrazole
Purity
98%
Packaging
5g
Price
$17.9
Updated
2024/03/01
Sigma-Aldrich
Product number
P56607
Product name
Pyrazole
Purity
98%
Packaging
25g
Price
$63.8
Updated
2024/03/01
Sigma-Aldrich
Product number
8.07572
Product name
Pyrazole
Purity
for synthesis
Packaging
25g
Price
$86
Updated
2024/03/01
TCI Chemical
Product number
P0546
Product name
Pyrazole
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$43
Updated
2024/03/01
TCI Chemical
Product number
P0546
Product name
Pyrazole
Purity
>98.0%(GC)(T)
Packaging
250g
Price
$118
Updated
2024/03/01
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Pyrazole Chemical Properties,Usage,Production

Chemical Properties

white to yellow crystals or crystalline powder

Uses

Pyrazole is used in organic synthesis and asa chelating agent.

Definition

ChEBI: 1H-pyrazole is the 1H-tautomer of pyrazole. It is a conjugate base of a pyrazolium. It is a conjugate acid of a pyrazol-1-ide. It is a tautomer of a 3H-pyrazole and a 4H-pyrazole.

General Description

Pyrazine is a heterocyclic crystalline aromatic compound with a five-membered ring containing three carbon atoms and two nitrogen atoms. It is a symmetricdiazine.

Hazard

Toxic by ingestion and inhalation, irritant to skin and eyes.

Health Hazard

The acute toxic symptoms from oral administrationof pyrazole in experimental animalswere ataxia, muscle weakness, and respiratorydepression. It is less toxic than pyrroleand pyrrolidine. The oral LD50 value in miceis within the range 1450 mg/kg.
Pyrazole exhibited reproductive toxicityin rats and mice when administered by oralor intraperitoneal route. The effects includefetal death, developmental abnormalities pertainingto the urogenital system, and postimplantationmortality.

Fire Hazard

Noncombustible solid.

Safety Profile

Moderately toxic by ingestion and intraperitoneal routes. Experimental teratogenic and reproductive effects. When heated to decomposition it emits toxic fumes of NOx.

Purification Methods

Crystallise pyrazole from pet ether, cyclohexane, or water. Its solubility in H2O at 9.6o is 2.7moles/L, and at 24.8o it is 19.4moles/L; in cyclohexane at 31.8o it is 0.577moles/L, and at 56.2o it is 5.86moles/L; and in benzene at 5.2o it is 0.31moles/L, and at 46.5o it is 16.8moles/1000mL. [Barszcz et al. J Chem Soc, Dalton Trans 2025 1986, Beilstein 23 H 39, 23 I 15, 23 II 33, 23 III/IV 550, 23/4 V 122.]

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Pyrazole Suppliers

TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
Nacalai Tesque, Inc.
Tel
--
Fax
--
Email
info-tech@nacalai.co.jp
Country
Japan
ProdList
6046
Advantage
75
Kanto Chemical Co., Inc.
Tel
--
Fax
--
Email
reag-info@gms.kanto.co.jp
Country
Japan
ProdList
6756
Advantage
74
Wako Pure Chemical Industries, Ltd.
Tel
--
Fax
--
Email
labchem-tec@wako-chem.co.jp
Country
Japan
ProdList
6819
Advantage
80
Junsei Chemical Co., Ltd.
Tel
--
Fax
--
Email
shiyaku@junsei.co.jp
Country
Japan
ProdList
3096
Advantage
46
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View Lastest Price from Pyrazole manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Pyrazole 288-13-1
Price
US $85.00-25.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-22
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Pyrazole 288-13-1
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-01-18
Yancheng Green Chemicals Co.,Ltd
Product
Pyrazole 288-13-1
Price
US $14000.00-120000.00/kg
Min. Order
1000kg
Purity
99%
Supply Ability
500 tons
Release date
2023-12-12

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