5-Amino-2-chloro-3-picoline

Product Name: 5-Amino-2-chloro-3-picoline
CAS No.: 38186-82-2
Chemical Name: 5-Amino-2-chloro-3-picoline
Synonyms: 5-Amin;oro-3-picoL;5-AMINO-2-CHLORO-3-PICOLINE;2-CHLORO-5-AMINO-3-PICOLINE;5-Amino-2-chloro-3-picoline ,97%;6-CHLORO-5-METHYLPYRIDIN-3-AMINE;6-Chloro-5-methyl-3-pyridinamine;3-amine-6-chloro-5-methylpyridine;5-AMINO-2-CHLORO-3-METHYLPYRIDINE;2-chloro-3-methyl-5-aminopyridine
CBNumber: CB7208306
Molecular Formula: C6H7ClN2
Formula Weight: 142.59
MOL File: 38186-82-2.mol

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5-Amino-2-chloro-3-picoline Property

Melting point:: 90.0 to 94.0 °C
Boiling point:: 304.7±37.0 °C(Predicted)
Density: 1.260±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
form: powder to crystalline
pka: 2.06±0.10(Predicted)
color: White to Brown
InChI: InChI=1S/C6H7ClN2/c1-4-2-5(8)3-9-6(4)7/h2-3H,8H2,1H3
InChIKey: VSBISZPNLZFTPG-UHFFFAOYSA-N
SMILES: C1=NC(Cl)=C(C)C=C1N
CAS DataBase Reference: 38186-82-2(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 22-37/38-41-36/37/38-20/21/22
Safety Statements: 26-39-36/37/39
RIDADR: 2811
WGK Germany: 3
HS Code: 29333990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 754854
Product name: 5-Amino-2-chloro-3-methylpyridine
Purity: 97%
Packaging: 1g
Price: $47.4
Updated: 2023/06/20

TCI Chemical

Product number: A2564
Product name: 5-Amino-2-chloro-3-methylpyridine
Purity: >97.0%(GC)(T)
Packaging: 5g
Price: $87
Updated: 2024/03/01

TRC

Product number: C381333
Product name: 6-Chloro-5-methylpyridin-3-amine
Packaging: 10mg
Price: $45
Updated: 2021/12/16

TRC

Product number: C381333
Product name: 6-Chloro-5-methylpyridin-3-amine
Packaging: 50mg
Price: $60
Updated: 2021/12/16

Matrix Scientific

Product number: 081311
Product name: 6-Chloro-5-methylpyridin-3-amine
Purity: 97%
Packaging: 1g
Price: $10
Updated: 2021/12/16

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5-Amino-2-chloro-3-picoline Chemical Properties,Usage,Production

Chemical Properties

Light yellow solid

Synthesis

22280-56-4

38186-82-2

The general procedure for the synthesis of 2-chloro-3-methyl-5-nitropyridine from 2-chloro-3-methyl-5-nitropyridine was as follows: over a period of 2 h, iron powder (9.75 g, 0.174 mol, Sigma-Aldrich) was added in batches to a stirred 2-chloro-3-methyl-5-nitropyridine (10 g, 0.058 mol, Combi) acetic acid/ water (29 mL:88 mL) solution. After 3 hours of reaction, the mixture was filtered through diatomaceous earth and the filter cake was washed with ethyl acetate. After separation of the organic layer, the aqueous layer was extracted with ethyl acetate. The combined organic layers were washed sequentially with aqueous sodium bicarbonate and brine and dried over anhydrous sodium sulfate. The solvent was removed by concentration under reduced pressure to give 6-chloro-5-methylpyridin-3-amine as a brown solid (8.0 g, 97% yield). Mass spectrum (MS) m/z = 142.03 [M + H]+. 1H-NMR (300 MHz, DMSO-d6) δ: 7.54 (d, J = 30 Hz, 1H), 6.91-6.90 (dd, J = 0.6 Hz and 2.7 Hz, 1H), 5.39 (s, 2H), 2.17 (s, 3H).

References

[1] Patent: WO2014/138484, 2014, A1. Location in patent: Page/Page column 156
[2] Patent: WO2016/22724, 2016, A1. Location in patent: Page/Page column 296
[3] Journal of Organic Chemistry, 2011, vol. 76, # 23, p. 9841 - 9844
[4] Synthetic Communications, 2006, vol. 36, # 9, p. 1235 - 1245
[5] Organic Letters, 2016, vol. 18, # 11, p. 2774 - 2776

5-Amino-2-chloro-3-picoline Preparation Products And Raw materials

Raw materials

Stannous chloride dihydrate Sodium dithionite Ethanol Calcium oxide Sodium sulfate 2-Amino-3-picoline Phosphorus oxitrichloride Sodium nitrite Diethyl ether Ethyl acetate Hydrochloric acid Nitric acid Sodium hydroxide Magnesium sulfate Sulfuric acid

Preparation Products

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5-Amino-2-chloro-3-picoline Suppliers

Americas 1 China 142 Europe 2 France 1 Germany 1 India 18 Japan 1 United Kingdom 9 United States 31 Global 206

Novasyn Organics Pvt. Ltd (France)

Tel: --
Fax: --
Country: France
ProdList: 303
Advantage: 58

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View Lastest Price from 5-Amino-2-chloro-3-picoline manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 5-AMINO-2-CHLORO-3-PICOLINE 38186-82-2
Price: US $1.10/g
Min. Order: 1g
Purity: 99.0% min
Supply Ability: 100 tons min
Release date: 2021-04-30

Zhuozhou Wenxi import and Export Co., Ltd

Product: 5-AMINO-2-CHLORO-3-PICOLINE 38186-82-2
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-11

Career Henan Chemical Co

Product: 5-AMINO-2-CHLORO-3-PICOLINE 38186-82-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 200kgs
Release date: 2020-01-09

38186-82-2, 5-Amino-2-chloro-3-picolineRelated Search:

3-Amino-2-chloro-4-methylpyridine 3-Amino-6-chloro-3-picoline,2-CHLORO-5-METHYLPYRIDIN-3-AMINE,5-AMINO-6-CHLORO-3-PICOLINE,3-AMINO-2-CHLORO-5-PICOLINE 2-Chloro-3-fluoropyridine 3-Amino-5-bromo-2-chloropyridine 2-Chloro-5-fluoronicotinonitrile 2-Chloro-3-pyridinamine 4-Bromo-2-chloro-3-iodopyridine 2-CHLORO-3-FLUORO-4-IODOPYRIDINE 6-Bromo-2-chloro-3-iodopyridine 2-Chloro-3-methyl-5-nitropyridine 2-Chloro-3-methyl-5-bromopyridine 2-Chloro-3-nitro-6-methylpyridine 2-Chloro-5-fluoro-3-methylpyridine 5-Bromo-2-chloro-3-fluoropyridine 3-AMINO-6-BROMO-2-CHLOROPYRIDINE 5-Bromo-2-chloro-3-nitropyridine 2-Chloro-3-iodopyridine 2-Chloro-4-methyl-3-nitropyridine

6-CHLORO-5-METHYLPYRIDIN-3-AMINE

6-CHLORO-5-METHYL-PYRIDIN-3-YLAMINE

2-chloro-3-methyl-5-aminopyridine

5-AMINO-2-CHLORO-3-METHYLPYRIDINE

2-CHLORO-5-AMINO-3-PICOLINE

5-AMINO-2-CHLORO-3-PICOLINE

5-Amino-2-chloro-3-picoline ,97%

3-amine-6-chloro-5-methylpyridine

6-Chloro-5-methyl-3-pyridinamine

6-Chloro-5-methylpyridin-3-amine, 5-Amino-2-chloro-3-picoline

3-phospho-D-glyceroyl dihydrogen phosphate

5-Amin

5-Amino-2-chloro-3-methylpyridine&gt

3-Pyridinamine, 6-chloro-5-methyl-

oro-3-picoL

5-AMINO-2-CHLORO-3-PICOLINE ISO 9001：2015 REACH

3-amine-2-chloro-5-methylpyridine

3-Methyl-2-chloro-5-aminopyridine

38186-82-2

8186-82-2

Pyridine

pharmacetical

Pyridine series

Amines

Pyridines