Bis-PEG4-acid

Product Name: Bis-PEG4-acid
CAS No.: 96517-92-9
Chemical Name: Bis-PEG4-acid
Synonyms: Di-Acid-PEG3;Bis-PEG3-COOH;Bis-PEG3-acid;COOH-PEG2-COOH;Bis-PEG3-acid ，S1350;HOOCCH2CH2O-PEG2-CH2CH2COOH;4,7,10-trioxa-tridecanedioic acid;3,3'-[oxybis(ethane-2,1-diyloxy)]dipropanoic acid;Propanoic acid, 3,3'-[oxybis(2,1-ethanediyloxy)]bis-;3-[2-[2-(2-carboxyethoxy)ethoxy]ethoxy]propanoic acid
CBNumber: CB73051642
Molecular Formula: C10H18O7
Formula Weight: 250.25
MOL File: 96517-92-9.mol

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Bis-PEG4-acid Property

Boiling point:: 445.4±40.0 °C(Predicted)
Density: 1.239±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Store in freezer, under -20°C
solubility: Soluble in Water, DMSO, DMF
pka: 3.97±0.10(Predicted)
form: Solid-Liquid Mixture
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: P999013
Product name: Bis-PEG3-acid
Packaging: 10mg
Price: $50
Updated: 2021/12/16

AK Scientific

Product number: 4904CU
Product name: Bis-PEG3-acid
Packaging: 1g
Price: $431
Updated: 2021/12/16

BroadPharm

Product number: BP-20584
Product name: Bis-PEG3-acid
Purity: 98%
Packaging: 250mg
Price: $125
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1248
Product name: Bis-PEG3-acid
Packaging: 250mg
Price: $468
Updated: 2021/12/16

Crysdot

Product number: CD13000320
Product name: 3,3'-((Oxybis(ethane-2,1-diyl))bis(oxy))dipropanoicacid
Purity: 97%
Packaging: 1g
Price: $520
Updated: 2021/12/16

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Bis-PEG4-acid Chemical Properties,Usage,Production

Description

Bis-PEG3-acid is a PEG linker containing two terminal carboxylic acid groups. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Uses

Bis-PEG3-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] Zhao Q, et al. Discovery of SIAIS178 as an Effective BCR-ABL Degrader by Recruiting Von Hippel-Lindau (VHL) E3 Ubiquitin Ligase. J Med Chem. 2019 Oct 24;62(20):9281-9298. DOI:10.1021/acs.jmedchem.9b01264

Bis-PEG4-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Bis-PEG4-acid Suppliers

China 76 India 1 United Kingdom 1 United States 6 Global 84

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

Accela ChemBio Inc.

Tel: +1-858-6993322
Fax: (+1)-858-876-1948
Email: info@accelachem.com
Country: United States
ProdList: 21193
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354;
Email: support@targetmol.com
Country: United States
ProdList: 39035
Advantage: 58

Aladdin Scientific

Tel
Email: tp@aladdinsci.com
Country: United States
ProdList: 52923
Advantage: 58

United States Biological

Tel: --
Fax: --
Email: chemicals@usbio.net
Country: United States
ProdList: 6214
Advantage: 80

PurePEG，LLC

Tel: --
Fax: --
Email: info@purepeg.com
Country: United States
ProdList: 697
Advantage: 58

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View Lastest Price from Bis-PEG4-acid manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Bis-PEG3-acid 96517-92-9
Price: US $0.00/g
Min. Order: 10g
Purity: >98.00%
Supply Ability: 10g
Release date: 2024-03-23

96517-92-9, Bis-PEG4-acidRelated Search:

Bis-Propargyl-PEG4 HO-PEG8-CH2CH2COOH Maleimide-PEG2-NHS Ester PEG5-acid HOOC-PEG7-CH2CH2COOH alpha, oMega-Dipropionic acid triethylene glycol α,ω-dipropionic acid tetraethylene glycol Bis-PEG2-acid Bis-PEG6-acid α,ω,-dipropionic acid nonaethylene glycol alpha-(2-Carboxyethyl)-omega-(2-carboxyethoxy)poly(oxy-1,2-ethanediyl) Bis-PEG4-t-butyl ester Bis-PEG10-acid alpha, oMega-Dipropionic acid hexaethylene glycol Bis-PEG6-t-butyl ester Bis-PEG1-NHS ester Bis-PEG5-t-butyl ester Bis-PEG9-t-butyl ester

Bis-PEG3-COOH

3,3'-[oxybis(ethane-2,1-diyloxy)]dipropanoic acid

Bis-PEG3-acid

3,3'-((Oxybis(ethane-2,1-diyl))bis(oxy))dipropanoic acid

COOH-PEG2-COOH

4,7,10-trioxa-tridecanedioic acid

HOOCCH2CH2O-PEG2-CH2CH2COOH

Propanoic acid, 3,3'-[oxybis(2,1-ethanediyloxy)]bis-

Di-Acid-PEG3

3,3'-((oxybis(ethane-2,1-diyl))bis(oxy))dipropionic acid

HOOCCH2CH2O-PEG2-CH2CH2COOH/4,7,10-Trioxatridecanedioic acid

3-[2-[2-(2-carboxyethoxy)ethoxy]ethoxy]propanoic acid

Bis-PEG3-acid ，S1350

96517-92-9