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trans-Cinnamic acid

Product Name
trans-Cinnamic acid
CAS No.
140-10-3
Chemical Name
trans-Cinnamic acid
Synonyms
3-PHENYLACRYLIC ACID;CINNAMIC ACID, TRANS-;3-PHENYL-2-PROPENOIC ACID;(E)-Cinnamic acid;(e)-2-propenoicaci;(E)-3-Phenylacrylic acid;TRANS-3-PHENYLACRYLIC ACID;trans-Cinnamicacid 140-10-3;(2E)-3-phenylprop-2-enoic acid;2-Propenoic acid, 3-phenyl-, (E)-
CBNumber
CB7345386
Molecular Formula
C9H8O2
Formula Weight
148.16
MOL File
140-10-3.mol
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trans-Cinnamic acid Property

Melting point:
133 °C (lit.)
Boiling point:
300 °C(lit.)
Density 
1.248
vapor pressure 
1.3 hPa (128 °C)
refractive index 
1.5049 (estimate)
Flash point:
>230 °F
storage temp. 
2-8°C
solubility 
0.4g/l
pka
4.44(at 25℃)
form 
Crystalline Powder
color 
White to almost white
Specific Gravity
0.91
Odor
Faint odour
PH Range
3 - 4
PH
3-4 (0.4g/l, H2O, 20℃)
Odor Type
balsamic
Water Solubility 
0.4 g/L (20 ºC)
λmax
273nm(MeOH)(lit.)
Merck 
14,2299
BRN 
1905952
Stability:
Light Sensitive
InChIKey
WBYWAXJHAXSJNI-VOTSOKGWSA-N
LogP
2.130
CAS DataBase Reference
140-10-3(CAS DataBase Reference)
NIST Chemistry Reference
Cinnamic acid(140-10-3)
EPA Substance Registry System
(E)-Cinnamic acid (140-10-3)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
1
RTECS 
GD7850000
TSCA 
Yes
HS Code 
29163900
Toxicity
LD50 orally in Rabbit: 2500 mg/kg LD50 dermal Rabbit > 5000 mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
W228826
Product name
trans-Cinnamic Acid
Purity
natural, ≥99%, FCC, FG
Packaging
25g
Price
$83.9
Updated
2024/03/01
Sigma-Aldrich
Product number
W228826
Product name
trans-Cinnamic Acid
Purity
natural, ≥99%, FCC, FG
Packaging
100g
Price
$159
Updated
2024/03/01
Sigma-Aldrich
Product number
W228826
Product name
trans-Cinnamic Acid
Purity
natural, ≥99%, FCC, FG
Packaging
1kg
Price
$656
Updated
2024/03/01
Sigma-Aldrich
Product number
W228818
Product name
trans-Cinnamic Acid
Purity
≥99%, FG
Packaging
1kg
Price
$80.9
Updated
2024/03/01
Sigma-Aldrich
Product number
W228818
Product name
trans-Cinnamic Acid
Purity
≥99%, FG
Packaging
10Kg
Price
$603
Updated
2024/03/01
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trans-Cinnamic acid Chemical Properties,Usage,Production

Chemical Properties

White to almost white crystalline powder. Insoluble in water, slightly soluble in hot water, easily soluble in benzene, acetone, ether, glacial acetic acid and other organic solvents.

Uses

trans-Cinnamic acid is used in flavors, synthetic indigo and pharmaceuticals. It is involved in the production of methyl, ethyl and benzyl esters, which is used in the perfume industry. It serves as a precursor to the sweetener aspartame through enzyme-catalyzed amination to phenylalanine. It is a self-inhibitor produced by fungal spores to prevent germination. In addition, it is used to establish phenolic compounds by liquid chromatography, ultraviolet and mass spectrometry. It is utilized as a potential agent, thereby preventing lung tumor cells from metastasizing. Further, it induces intracellular release of calcium ions from the vacuole to the cytoplasm in order to trigger phytotoxicity in cucumber.

Uses

trans-Cinnamic acid was used to establish library of phenolic compounds by liquid chromatography/ultraviolet and mass spectrometry/mass spectrometry.

Definition

ChEBI: Cinnamic acid is a monocarboxylic acid that consists of acrylic acid bearing a phenyl substituent at the 3-position. It is found in Cinnamomum cassia. It has a role as a plant metabolite. It is a member of styrenes and a member of cinnamic acids. It is a conjugate acid of a cinnamate.

General Description

trans-Cinnamic acid is an α,β-unsaturated aromatic acid that can be used as a flavoring agent. It is mainly used to prepare ester derivatives that are used in perfume industry. trans-Cinnamic acid is the key volatile components of cinnamon essential oil.

Flammability and Explosibility

Not classified

Biochem/physiol Actions

trans-cinnamic acid has inhibitory effect on phorbol-12-myristate-13-acetate-induced invasion of human lung adenocarcinoma A549 cells. It is a potential agent which can prevent lung tumor cells from metastasizing. It induces intracellular release of Ca2+ from the vacuole to the cytoplasm which triggers phytotoxicity in cucumber.

Purification Methods

Crystallise the acid from *benzene, CCl4, hot water, water/EtOH (3:1), or 20% aqueous EtOH. Dry it at 60o in vacuo. It is steam volatile. [Beilstein 9 IV 2002.]

trans-Cinnamic acid Preparation Products And Raw materials

Raw materials

Acetic anhydride Glass-lined reaction pot

Preparation Products

Cinnamic acid Docetaxel 3-CHLORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID HYDRAZIDE alpha-Amylcinnamaldehyde 3-CHLOROBENZO[B]THIOPHENE-2-CARBOXAMIDE Dihydrocoumarin 3-CHLOROBENZO[B]THIOPHENE-2-CARBONYL CHLORIDE Cinnamyl cinnamate Methyl cinnamate Lacidipine METHYL 3-CHLOROBENZO[B]THIOPHENE-2-CARBOXYLATE 3-CHLOROBENZO[B]THIOPHENE-2-CARBOXYLIC ACID Cinnamyl alcohol Benzyl cinnamate Phenylacetaldehyde 4-Hydroxy-3-methoxystyrene ALLYL CINNAMATE Ethyl cinnamate cyclamen aldehyde
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View Lastest Price from trans-Cinnamic acid manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Trans-Cinnamic Acid 140-10-3
Price
US $200.00-95.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-04-29
HebeiShuoshengImportandExportco.,Ltd
Product
trans-Cinnamic acid 140-10-3
Price
US $6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000KG/Month
Release date
2024-08-08
Hebei Longbang Technology Co., Ltd
Product
trans-Cinnamic acid 140-10-3
Price
US $6.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20TONS
Release date
2024-05-10

140-10-3, trans-Cinnamic acidRelated Search:

Acrylic acid 4-Methoxycinnamic acid Methyl propiolate 3-(Trifluoromethyl)cinnamic acid trans,trans-2,4-Undecadienal Methyl acrylate Methacrylic acid Diphenyl ether Phenyl salicylate 6-Benzylaminopurine Methyl methacrylate Butyl acrylate Poly(acrylic acid) PHENYL VALERATE Methyl cinnamate Ethyl acrylate trans-Cinnamic acid allyl ester Cinnamaldehyde

  • (e)-2-propenoicaci
  • (E)-3-Phenyl-2-propenoic acid
  • Nat.trans-Cinnamic acid
  • trans-Cinnamicacid 140-10-3
  • trans-Cinnamic acid, AR,99%
  • trans-Cinnamic acid, CP,98%
  • CINNAMIC ACID, TRANS-(SG)
  • trans-Ciamic acid
  • (2E)-3-Phenylprop-2-enoic acid, (E)-3-Phenylacrylic acid
  • trans-Cinamic acid
  • CINNAMIC ACID extrapure
  • cinnamic acid，β-phenyl acrylic acid
  • trans-b-Carboxystyrene
  • (E)-3-Phenylpropenoic acid
  • CINNAMIC ACID, TRANS-
  • FEMA 2288
  • BETA-PHENYLACRYLIC ACID
  • RARECHEM BK HC T302
  • 2-PROPENOIC ACID, 3-PHENYL-, (2E)-
  • AKOS B004228
  • AKOS 233-01
  • 3-PHENYL-2-PROPENOIC ACID
  • 3-PHENYLACRYLIC ACID
  • 3-STYRYLACRYLIC ACID
  • trans-CinnaMic acid, 98+% 100GR
  • trans-CinnaMic acid, 98+% 500GR
  • trans-CinnaMic acid, 98+% 5GR
  • trans-Cinnamic acid,trans-3-Phenylacrylic acid, Cinnamic acid
  • Hedyotis diffusa Willd.
  • (e)-3-phenyl-2-propenoicacid
  • (E)-Cinnamic acid
  • (e)-cinnamicaci
  • (e)-cinnamicacid
  • (E)-Zimtsαure
  • 2-Propenoic acid, 3-phenyl-, (E)-
  • 2-propenoicacid,3-phenyl-
  • 2-Propenoicacid,3-phenyl-,
  • 3-Phenylpropensαure
  • Benzalaceticacid
  • Cinnamic acid, (E)-
  • -Phenylpropenoicacid
  • trans-3-Phenyl-2-Propenoic acid
  • trans-beta-Carboxystyrene
  • trans-cinnamic
  • trans-Zimtsαure
  • Zimtsαure
  • trans-Cinnamic acid (trans-3-Phenylacrylic acid)
  • trans-Cinnamic Acid Zone Refined
  • trans-Cinnamic acid (Synonyms: trans-3-Phenylacrylic acid)
  • Cinnamic acid,trans-Cinnamic acid
  • trans-Cinnamic Acid [Matrix for MALDI-TOF/MS]
  • C**trans-Cinnamic acid
  • Cinnamic acid, Cinnamyl acid
  • Cinnamin acid
  • TRANS-3-PHENYLACRYLIC ACID
  • TRANS-3-BENZENEPROPENOIC ACID
  • TRANS-3-PHENYLPROPENOIC ACID
  • TRANS-CINNAMIC ACID