trans-Cinnamic acid

Product Name: trans-Cinnamic acid
CAS No.: 140-10-3
Chemical Name: trans-Cinnamic acid
Synonyms: 3-PHENYLACRYLIC ACID;CINNAMIC ACID, TRANS-;3-PHENYL-2-PROPENOIC ACID;(E)-Cinnamic acid;(e)-2-propenoicaci;(E)-3-Phenylacrylic acid;TRANS-3-PHENYLACRYLIC ACID;trans-Cinnamicacid 140-10-3;(2E)-3-phenylprop-2-enoic acid;2-Propenoic acid, 3-phenyl-, (E)-
CBNumber: CB7345386
Molecular Formula: C9H8O2
Formula Weight: 148.16
MOL File: 140-10-3.mol

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trans-Cinnamic acid Property

Melting point:: 133 °C (lit.)
Boiling point:: 300 °C(lit.)
Density: 1.248
vapor pressure: 1.3 hPa (128 °C)
refractive index: 1.5049 (estimate)
Flash point:: >230 °F
storage temp.: 2-8°C
solubility: 0.4g/l
pka: 4.44(at 25℃)
form: Crystalline Powder
color: White to almost white
Specific Gravity: 0.91
Odor: Faint odour
PH Range: 3 - 4
PH: 3-4 (0.4g/l, H2O, 20℃)
Odor Type: balsamic
Water Solubility: 0.4 g/L (20 ºC)
λmax: 273nm(MeOH)(lit.)
Merck: 14,2299
BRN: 1905952
Stability:: Light Sensitive
InChIKey: WBYWAXJHAXSJNI-VOTSOKGWSA-N
LogP: 2.130
CAS DataBase Reference: 140-10-3(CAS DataBase Reference)
NIST Chemistry Reference: Cinnamic acid(140-10-3)
EPA Substance Registry System: (E)-Cinnamic acid (140-10-3)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-37/39
WGK Germany: 1
RTECS: GD7850000
TSCA: Yes
HS Code: 29163900
Toxicity: LD50 orally in Rabbit: 2500 mg/kg LD50 dermal Rabbit > 5000 mg/kg

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: W228826
Product name: trans-Cinnamic Acid
Purity: natural, ≥99%, FCC, FG
Packaging: 25g
Price: $83.9
Updated: 2024/03/01

Sigma-Aldrich

Product number: W228826
Product name: trans-Cinnamic Acid
Purity: natural, ≥99%, FCC, FG
Packaging: 100g
Price: $159
Updated: 2024/03/01

Sigma-Aldrich

Product number: W228826
Product name: trans-Cinnamic Acid
Purity: natural, ≥99%, FCC, FG
Packaging: 1kg
Price: $656
Updated: 2024/03/01

Sigma-Aldrich

Product number: W228818
Product name: trans-Cinnamic Acid
Purity: ≥99%, FG
Packaging: 1kg
Price: $80.9
Updated: 2024/03/01

Sigma-Aldrich

Product number: W228818
Product name: trans-Cinnamic Acid
Purity: ≥99%, FG
Packaging: 10Kg
Price: $603
Updated: 2024/03/01

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trans-Cinnamic acid Chemical Properties,Usage,Production

Chemical Properties

White to almost white crystalline powder. Insoluble in water, slightly soluble in hot water, easily soluble in benzene, acetone, ether, glacial acetic acid and other organic solvents.

Uses

trans-Cinnamic acid is used in flavors, synthetic indigo and pharmaceuticals. It is involved in the production of methyl, ethyl and benzyl esters, which is used in the perfume industry. It serves as a precursor to the sweetener aspartame through enzyme-catalyzed amination to phenylalanine. It is a self-inhibitor produced by fungal spores to prevent germination. In addition, it is used to establish phenolic compounds by liquid chromatography, ultraviolet and mass spectrometry. It is utilized as a potential agent, thereby preventing lung tumor cells from metastasizing. Further, it induces intracellular release of calcium ions from the vacuole to the cytoplasm in order to trigger phytotoxicity in cucumber.

Uses

trans-Cinnamic acid was used to establish library of phenolic compounds by liquid chromatography/ultraviolet and mass spectrometry/mass spectrometry.

Definition

ChEBI: Cinnamic acid is a monocarboxylic acid that consists of acrylic acid bearing a phenyl substituent at the 3-position. It is found in Cinnamomum cassia. It has a role as a plant metabolite. It is a member of styrenes and a member of cinnamic acids. It is a conjugate acid of a cinnamate.

General Description

trans-Cinnamic acid is an α,β-unsaturated aromatic acid that can be used as a flavoring agent. It is mainly used to prepare ester derivatives that are used in perfume industry. trans-Cinnamic acid is the key volatile components of cinnamon essential oil.

Flammability and Explosibility

Not classified

Biochem/physiol Actions

trans-cinnamic acid has inhibitory effect on phorbol-12-myristate-13-acetate-induced invasion of human lung adenocarcinoma A549 cells. It is a potential agent which can prevent lung tumor cells from metastasizing. It induces intracellular release of Ca2+ from the vacuole to the cytoplasm which triggers phytotoxicity in cucumber.

Purification Methods

Crystallise the acid from *benzene, CCl4, hot water, water/EtOH (3:1), or 20% aqueous EtOH. Dry it at 60o in vacuo. It is steam volatile. [Beilstein 9 IV 2002.]

trans-Cinnamic acid Preparation Products And Raw materials

Raw materials

Acetic anhydride Glass-lined reaction pot

Preparation Products

Cinnamic acid Docetaxel 3-CHLORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID HYDRAZIDE alpha-Amylcinnamaldehyde 3-CHLOROBENZO[B]THIOPHENE-2-CARBOXAMIDE Dihydrocoumarin 3-CHLOROBENZO[B]THIOPHENE-2-CARBONYL CHLORIDE Cinnamyl cinnamate Methyl cinnamate Lacidipine METHYL 3-CHLOROBENZO[B]THIOPHENE-2-CARBOXYLATE 3-CHLOROBENZO[B]THIOPHENE-2-CARBOXYLIC ACID Cinnamyl alcohol Benzyl cinnamate Phenylacetaldehyde 4-Hydroxy-3-methoxystyrene ALLYL CINNAMATE Ethyl cinnamate cyclamen aldehyde

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View Lastest Price from trans-Cinnamic acid manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: Trans-Cinnamic Acid 140-10-3
Price: US $200.00-95.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-04-29

HebeiShuoshengImportandExportco.,Ltd

Product: trans-Cinnamic acid 140-10-3
Price: US $6.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000KG/Month
Release date: 2024-08-08

Hebei Longbang Technology Co., Ltd

Product: trans-Cinnamic acid 140-10-3
Price: US $6.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20TONS
Release date: 2024-05-10

140-10-3, trans-Cinnamic acidRelated Search:

Acrylic acid 4-Methoxycinnamic acid Methyl propiolate 3-(Trifluoromethyl)cinnamic acid trans,trans-2,4-Undecadienal Methyl acrylate Methacrylic acid Diphenyl ether Phenyl salicylate 6-Benzylaminopurine Methyl methacrylate Butyl acrylate Poly(acrylic acid) PHENYL VALERATE Methyl cinnamate Ethyl acrylate trans-Cinnamic acid allyl ester Cinnamaldehyde

(e)-2-propenoicaci

(E)-3-Phenyl-2-propenoic acid

Nat.trans-Cinnamic acid

trans-Cinnamicacid 140-10-3

trans-Cinnamic acid, AR,99%

trans-Cinnamic acid, CP,98%

CINNAMIC ACID, TRANS-(SG)

trans-Ciamic acid

(2E)-3-Phenylprop-2-enoic acid, (E)-3-Phenylacrylic acid

trans-Cinamic acid

CINNAMIC ACID extrapure

cinnamic acid，β-phenyl acrylic acid

trans-b-Carboxystyrene

(E)-3-Phenylpropenoic acid

CINNAMIC ACID, TRANS-

FEMA 2288

BETA-PHENYLACRYLIC ACID

RARECHEM BK HC T302

2-PROPENOIC ACID, 3-PHENYL-, (2E)-

AKOS B004228

AKOS 233-01

3-PHENYL-2-PROPENOIC ACID

3-PHENYLACRYLIC ACID

3-STYRYLACRYLIC ACID

trans-CinnaMic acid, 98+% 100GR

trans-CinnaMic acid, 98+% 500GR

trans-CinnaMic acid, 98+% 5GR

trans-Cinnamic acid,trans-3-Phenylacrylic acid, Cinnamic acid

Hedyotis diffusa Willd.

(e)-3-phenyl-2-propenoicacid

(E)-Cinnamic acid

(e)-cinnamicaci

(e)-cinnamicacid

(E)-Zimtsαure

2-Propenoic acid, 3-phenyl-, (E)-

2-propenoicacid,3-phenyl-

2-Propenoicacid,3-phenyl-,

3-Phenylpropensαure

Benzalaceticacid

Cinnamic acid, (E)-

-Phenylpropenoicacid

trans-3-Phenyl-2-Propenoic acid

trans-beta-Carboxystyrene

trans-cinnamic

trans-Zimtsαure

Zimtsαure

trans-Cinnamic acid (trans-3-Phenylacrylic acid)

trans-Cinnamic Acid Zone Refined

trans-Cinnamic acid (Synonyms: trans-3-Phenylacrylic acid)

Cinnamic acid,trans-Cinnamic acid

trans-Cinnamic Acid [Matrix for MALDI-TOF/MS]

C**trans-Cinnamic acid

Cinnamic acid, Cinnamyl acid

Cinnamin acid

TRANS-3-PHENYLACRYLIC ACID

TRANS-3-BENZENEPROPENOIC ACID

TRANS-3-PHENYLPROPENOIC ACID

TRANS-CINNAMIC ACID