1-Methyl-1H-imidazole-2-carboxylic acid
- Product Name
- 1-Methyl-1H-imidazole-2-carboxylic acid
- CAS No.
- 20485-43-2
- Chemical Name
- 1-Methyl-1H-imidazole-2-carboxylic acid
- Synonyms
- RARECHEM AL BE 0638;IFLAB-BB F2124-0530;CHEMBRDG-BB 4401397;1-methyl-2-imidazolecarboxylic acid;1-METHYLIMIDAZOLE-2-CARBOXYLIC ACID;1- MethyliMidazolecarboxylate-1H--2-;1-METHYL-1H-IMIDAZOLE-CARBOXYLIC ACID;1-Methyl-1H-2-iMidazolecarboxylic Acid;Imidazole-2-carboxylic acid, 1-methyl-;1-METHYL-1H-IMIDAZOLE-2-CARBOXYLIC ACID
- CBNumber
- CB7366839
- Molecular Formula
- C5H6N2O2
- Formula Weight
- 126.11
- MOL File
- 20485-43-2.mol
1-Methyl-1H-imidazole-2-carboxylic acid Property
- Melting point:
- 104 °C (dec.)
- Boiling point:
- 339.4±25.0 °C(Predicted)
- Density
- 1.34±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- Methanol (Slightly), Water (Slightly)
- form
- Solid
- pka
- 1.24±0.31(Predicted)
- color
- White to Off-White
- Sensitive
- Hygroscopic
- Stability:
- Temperature Sensitive
- InChI
- InChI=1S/C5H6N2O2/c1-7-3-2-6-4(7)5(8)9/h2-3H,1H3,(H,8,9)
- InChIKey
- WLDPWZQYAVZTTP-UHFFFAOYSA-N
- SMILES
- C1(C(O)=O)N(C)C=CN=1
- CAS DataBase Reference
- 20485-43-2(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37/39-37/39-36
- WGK Germany
- 3
- Hazard Note
- Irritant
- HS Code
- 29332900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 576220
- Product name
- 1-Methyl-1H-imidazole-2-carboxylic acid
- Purity
- technical grade, 90%
- Packaging
- 1g
- Price
- $53
- Updated
- 2023/06/20
- Product number
- M313000
- Product name
- 1-Methylimidazole-2-carboxylicAcid
- Packaging
- 5g
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 282754
- Product name
- 1-Methylimidazole-2-carboxylic acid
- Packaging
- 1g
- Price
- $375
- Updated
- 2021/12/16
- Product number
- 093196
- Product name
- 1-Methyl-1H-imidazole-2-carboxylic acid
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $19
- Updated
- 2021/12/16
- Product number
- J93373
- Product name
- 1-Methyl-1H-imidazole-2-carboxylic acid
- Packaging
- 1g
- Price
- $25
- Updated
- 2021/12/16
1-Methyl-1H-imidazole-2-carboxylic acid Chemical Properties,Usage,Production
Chemical Properties
White Crystalline Solid
Uses
It is useful for solid phase synthesis of polyamides containing imidazole.
Uses
1-Methyl-1H-imidazole-2-carboxylic acid is a useful synthetic intermediate for solid phase synthesis of polyamides containing imidazole
Definition
ChEBI: 1-methyl-imidazole-2-carboxylic acid is an imidazolyl carboxylic acid that is 1H-imidazole with methyl and carboxylic acid group substituents at positions 1 and 2 respectively. It has a role as a metabolite.
Synthesis
13750-81-7
20485-43-2
The general procedure for the synthesis of 1-methyl-1H-imidazole-2-carboxylic acid from 1-methyl-1H-imidazole-2-carboxaldehyde is as follows: first, 1-methyl-1H-imidazole-2-carboxaldehyde was prepared by referring to the method described in literature [23]. Subsequently, the synthetic procedure for Im2COOH (1b) was followed, and the reaction yield was up to quantitative levels after removal of water under high vacuum (without diethyl ether/water washing). Note that heating may cause decarboxylation to occur. Product yield: 100%. Melting point range is 99-101 °C. NMR hydrogen spectrum (400MHz, D2O): δH 7.42, 7.39 (2H, single peak, imidazolium cyclic-H), 4.08 ppm (3H, single peak, N-CH3); NMR carbon spectrum (400MHz, D2O): δC 158.67, 139.68, 125.83, 118.46, 36.73 ppm. infrared spectrum ( KBr press method): ν 3347 (medium intensity), 3119 (medium intensity), 2663 (weak), 1641 (strong), 1683 (medium intensity), 1507 (strong), 1449 (medium intensity), 1388 (strong), 1338 (strong), 1285 (strong), 1173 (medium intensity), 1123 (strong), 961 (medium intensity), 910 (medium), 776 (strong), 685 (strong) cm-1. Calculated values from elemental analysis (C5H8N2O3, molecular weight 144.12): C, 41.67%; H, 5.59%; N, 19.44%. Measured values: C, 41.28%; H, 5.23%; N, 19.12%.
References
[1] South African Journal of Chemistry, 2010, vol. 63, p. 95 - 104
[2] Journal of Inorganic Biochemistry, 2015, vol. 145, p. 11 - 18
[3] South African Journal of Chemistry, 2012, vol. 65, p. 231 - 238
1-Methyl-1H-imidazole-2-carboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
1-Methyl-1H-imidazole-2-carboxylic acid Suppliers
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View Lastest Price from 1-Methyl-1H-imidazole-2-carboxylic acid manufacturers
- Product
- 1-Methyl-1H-imidazole-2-carboxylic acid 20485-43-2
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-27
- Product
- 1-Methyl-1H-imidazole-2-carboxylic acid 20485-43-2
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2018-12-21