2-Methyl-4-nitroaniline Property

Melting point:

130-132 °C(lit.)

Boiling point:

294.61°C (rough estimate)

Density 

1.1586

vapor pressure 

20.4hPa at 133.5℃

refractive index 

1.6276 (estimate)

Flash point:

157.2℃

storage temp. 

Store below +30°C.

solubility 

Dichloromethane, DMSO, Ethyl Acetate, Methanol

form 

Crystalline Powder or Fine Needles

pka

0.92±0.10(Predicted)

Colour Index 

37100

color 

Yellow to khaki or brownish

PH

7 (H2O)(aqueous suspension)

Water Solubility 

<0.1 g/100 mL at 22 ºC

BRN 

775772

LogP

1.311 at 25℃

CAS DataBase Reference

99-52-5(CAS DataBase Reference)

NIST Chemistry Reference

5-Nitro-2-aminotoluene(99-52-5)

EPA Substance Registry System

2-Methyl-4-nitroaniline (99-52-5)

Safety

Hazard Codes 

T,N,Xi

Risk Statements 

23/24/25-33-51/53

Safety Statements 

28-36/37-45-61-28A

RIDADR 

UN 2660 6.1/PG 3

WGK Germany 

2

RTECS 

XU8210000

Hazard Note 

Irritant

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

III

HS Code 

29214300

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H373May cause damage to organs through prolonged or repeated exposure

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P314Get medical advice/attention if you feel unwell.

2-Methyl-4-nitroaniline Chemical Properties,Usage,Production

Description

2-Methyl-4-nitroaniline was used in preparing in-plane aligned nanofibers by the electrospinning technique. It was the starting reagent in the synthesis of 3-chloro-5-methylphenyl isocyanate. It was used to deposit polycrystalline thin films on Ag, Cu and Si by conventional and partially ionized beam deposition.

Reference

2. Seo, Kang, and C. Bonner. "Growth of organic thin films on Si (100) surfaces: 2-Methyl-4-Nitroaniline (MNA)." APS Southeastern Section Meeting APS Southeastern Section Meeting Abstracts, 2002.

Chemical Properties

Yellowneedle

Uses

A red azoic dye.

Uses

2-Methyl-4-nitroaniline was used in preparing in-plane aligned nanofibers by the electrospinning technique. It was the starting reagent in the synthesis of 3-chloro-5-methylphenyl isocyanate. It was used to deposit polycrystalline thin films on Ag, Cu and Si by conventional and partially ionized beam deposition.

Production Methods

N-Benzenesulfonyl-o-toluidine is dissolved in chlorobenzene at 40 – 50 ℃, and 62 % nitric acid is added gradually to give 5- nitro-N-benzenesulfonyl-o-toluidine, which is isolated and hydrolyzed in sulfuric acid to give 5-nitro-o-toluidine in 80 % yield.

General Description

Yellow needles or mustard yellow powder.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

2-Methyl-4-nitroaniline is incompatible with acids, acid chlorides, acid anhydrides, chloroformates and strong oxidizing agents.

Fire Hazard

Flash point data for 2-Methyl-4-nitroaniline are not available; however, 2-Methyl-4-nitroaniline is probably combustible.

Purification Methods

Crystallise the nitrotoluidine from EtOH. The acetyl and benzoyl derivatives have m 200o and 174o (EtOH) respectively. [Beilstein 12 IV 1809.]