ChemicalBook > CAS DataBase List > 2-Chloro-4-picoline

2-Chloro-4-picoline

Product Name
2-Chloro-4-picoline
CAS No.
3678-62-4
Chemical Name
2-Chloro-4-picoline
Synonyms
2-CHLORO-4-METHYLPYRIDINE;2-CHLOROPICOLINE;2-CHLORO-4-PICOLINE;2-Chloro-4-Pilcoline;4-Picoline, 2-chloro-;2-CHLORO-GAMMA-PICOLINE;2-Chlor-4-methylpyridin;2-Chloro-4-picoline,98%;2-chloro-4-methylpyrdine;2-Chloro-4-mehyl pyridine
CBNumber
CB7481718
Molecular Formula
C6H6ClN
Formula Weight
127.57
MOL File
3678-62-4.mol
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2-Chloro-4-picoline Property

Melting point:
115°C
Boiling point:
194-195 °C (lit.)
Density 
1.142 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.529(lit.)
Flash point:
193 °F
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
Liquid
pka
0.94±0.10(Predicted)
Specific Gravity
1.14
color 
Clear colorless to light yellow
InChI
InChI=1S/C6H6ClN/c1-5-2-3-8-6(7)4-5/h2-4H,1H3
InChIKey
MZVSTDHRRYQFGI-UHFFFAOYSA-N
SMILES
C1(Cl)=NC=CC(C)=C1
CAS DataBase Reference
3678-62-4(CAS DataBase Reference)
NIST Chemistry Reference
2-Cl-4-(CH3)-pyridine(3678-62-4)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-20/21/22
Safety Statements 
26-36-36/37/39
WGK Germany 
3
HazardClass 
IRRITANT, IRRITANT-HARMFUL
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
116327
Product name
2-Chloro-4-methylpyridine
Purity
98%
Packaging
5ml
Price
$44.4
Updated
2024/03/01
Sigma-Aldrich
Product number
116327
Product name
2-Chloro-4-methylpyridine
Purity
98%
Packaging
25ml
Price
$105.6
Updated
2024/03/01
TCI Chemical
Product number
C1992
Product name
2-Chloro-4-methylpyridine
Purity
>98.0%(GC)
Packaging
5g
Price
$27
Updated
2024/03/01
TCI Chemical
Product number
C1992
Product name
2-Chloro-4-methylpyridine
Purity
>98.0%(GC)
Packaging
25g
Price
$75
Updated
2024/03/01
Alfa Aesar
Product number
H60607
Product name
2-Chloro-4-methylpyridine, 98%
Packaging
5ml
Price
$49.9
Updated
2021/12/16
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2-Chloro-4-picoline Chemical Properties,Usage,Production

Chemical Properties

Colorless to light yellow liquid.

Uses

2-Chloro-4-methylpyridine is used as a reagent in the synthesis of the mGLUR5 modulators imidazolyl-ethynyl-pyridines as potential antipsychotics. It is also used in the preparation of trifluoromethyl(pyrimidinyl)azetidinecarboxamides as potent, orally bioavailable TGR5 agonists.

General Description

2-Chloro-4-methylpyridine (2-Chloro-4-picoline) reacts with 3,5-bis(trifluoromethyl)phenylboronic acid to form 2-(3,5-bis(trifluoromethyl)phenyl)-4-methylpyridine by palladium-catalyzed cross-coupling reaction.

2-Chloro-4-picoline Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Chloro-4-picoline Suppliers

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View Lastest Price from 2-Chloro-4-picoline manufacturers

Hebei Yanxi Chemical Co., Ltd.
Product
2-Chloro-4-picoline 3678-62-4
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98.00%
Supply Ability
100tons
Release date
2023-09-27
Hebei Chuanghai Biotechnology Co,.LTD
Product
2-Chloro-4-Methylpyridine 3678-62-4
Price
US $19.10/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 ton
Release date
2024-08-09
Henan Fengda Chemical Co., Ltd
Product
2-Chloro-4-picoline 3678-62-4
Price
US $9.00-0.90/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-01-23

3678-62-4, 2-Chloro-4-picolineRelated Search:

2-Chloro-5-chloromethylpyridine Clopidol 2,6-Lutidine Pentachloropyridine Epichlorohydrin 2-Chloro-3-cyanopyridine 2-Chloro-4-nitropyridine 2-(Chloromethyl)pyridine 4-Methylpyridine Azamethiphos 2,4,6-Collidine Chloroacetic acid 2-Chloro-4-(trifluoromethyl)pyridine 2,6-Dichloro-4-(trifluoromethyl)pyridine ETHYL 2-CHLORO-3-CYANO-6-METHYLISONICOTINATE METHYL 2,6-DICHLOROISONICOTINATE 2-CHLOROLEPIDINE 2-Chloro-4-methyl-3-nitropyridine

  • 2-Chlor-4-methylpyridin
  • 2-Chlor2-Chloro-4-picolineo-4-picoline
  • 2-Chloro-4-mehyl pyridine
  • 4-Picoline, 2-chloro-
  • Pyridine, 2-chloro-4-methyl-
  • 2-CHLORO-GAMMA-PICOLINE
  • 2-CHLOROPICOLINE
  • 2-CHLORO-4-PICOLINE
  • 2-CHLORO-4-METHYLPYRIDINE
  • 2-chloro-4-methylpyrdine
  • 2-CHLORO-4-PICOLINE 2-CHLORO-4-METHYLPYRIDINE
  • 2-CHLORO-4-METHYLPYRIDINE (2-CHLORO-4-PICOLINE)
  • HCPY1902-Chloro-4-picoline
  • 2-Chloro-4-methylpyridine(2-Chloropicoline)
  • 2-Chloro-4-picoline,98%
  • 2-Chloro-4-Pilcoline
  • 2-Chloro-4-methylpyridine &gt
  • 5-bromopyridine-4-carbonitrile
  • 2-Chloro-4-picoline ISO 9001：2015 REACH
  • 3678-62-4
  • 222-951-2
  • C6H6ClN
  • Building Blocks
  • HETERO CHLORIDE
  • Halopyridines
  • Chloropyridines
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • Pyridines
  • Pyridine
  • pyridine derivative
  • pyridine series
  • Chloropyridines
  • Halopyridines
  • Halides
  • Pyridines