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2,5-Dichloropyrimidine

Product Name
2,5-Dichloropyrimidine
CAS No.
22536-67-0
Chemical Name
2,5-Dichloropyrimidine
Synonyms
EOS-60492;2,5-Dichlo;2,5-chloropyrimidine;2,5-DICHLOROPYRIMIDINE;Macitentan Impurity 32;2,5‐Dichloropyridimidine;2,5-Dichloro-1,3-diazine;Pyrimidine, 2,5-dichloro-;2,5-Dichloropyrimidine>2,5-Dichloropyrimidine 97%
CBNumber
CB7750461
Molecular Formula
C4H2Cl2N2
Formula Weight
148.98
MOL File
22536-67-0.mol
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2,5-Dichloropyrimidine Property

Melting point:
48-55 °C
Boiling point:
190°C
Density 
1.493
Flash point:
140°C
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
pka
-2.84±0.22(Predicted)
form 
Powder
color 
Off-white
Water Solubility 
Slightly soluble in water.
λmax
268nm(EtOH)(lit.)
InChI
InChI=1S/C4H2Cl2N2/c5-3-1-7-4(6)8-2-3/h1-2H
InChIKey
CEJAHXLRNZJPQH-UHFFFAOYSA-N
SMILES
C1(Cl)=NC=C(Cl)C=N1
CAS DataBase Reference
22536-67-0(CAS DataBase Reference)
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Safety

Hazard Codes 
C,N,Xn
Risk Statements 
22-41-50
Safety Statements 
26-39-61
RIDADR 
UN 3077 9/PG 3
WGK Germany 
2
HazardClass 
LACHRYMATOR, CORROSIVE
HazardClass 
9
PackingGroup 
Ⅲ
HS Code 
29335990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
720917
Product name
2,5-Dichloropyrimidine
Purity
97%
Packaging
1g
Price
$10.4
Updated
2024/03/01
TCI Chemical
Product number
D4045
Product name
2,5-Dichloropyrimidine
Purity
>98.0%(GC)
Packaging
5g
Price
$37
Updated
2024/03/01
TCI Chemical
Product number
D4045
Product name
2,5-Dichloropyrimidine
Purity
>98.0%(GC)
Packaging
25g
Price
$148
Updated
2024/03/01
Alfa Aesar
Product number
H64066
Product name
2,5-Dichloropyrimidine, 95%
Packaging
5g
Price
$32.65
Updated
2024/03/01
Alfa Aesar
Product number
H64066
Product name
2,5-Dichloropyrimidine, 95%
Packaging
25g
Price
$127.65
Updated
2024/03/01
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2,5-Dichloropyrimidine Chemical Properties,Usage,Production

Uses

2,5-Dichloropyrimidine acid is employed as a important raw material and intermediate used in organic synthesis agrochemical, pharmaceutical and dyestuff field.

Preparation

2,5-Dichloropyrimidine was synthesised from 2-hydroxypyrimidine hydrochloride by treatment with aqueous chlorine solution. Reaction of the product with phosphoryl chloride in the presence of N,N-dimethylaniline gave the desired product in 40% yield. The sample was then purified by sublimation.

storage

Store in cool, dry place in tightly closed container. With adequate ventilation. Store away from oxidizing agent.

structure and hydrogen bonding

C4H2Cl2N2, M=148.98 monoclinic, space group P21/m with a=6.077(3), b=19.771(8), c=7.399(3) ?, β=101.23(6)°, U=872 ?3 [from 2θ values of 29 reflections measured at±ω, 25 ≤2θ ≤ 38°, λ = 0.710 73?, T=150.0 K], Dcalc=1.702 g cm-3, Z=6, μ =0.993 mm-1[1].

References

[1] Blake A, et al. Structure Analysis Restrained by ab Initio Calculations: The Molecular Structure of 2,5-Dichloropyrimidine in Gaseous and Crystalline Phases. The Journal of Physical Chemistry, 1996; 100: 12280–12287.

2,5-Dichloropyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

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2,5-Dichloropyrimidine Suppliers

Americas 1 Canada 3 China 244 Europe 2 Germany 3 India 11 Japan 1 Switzerland 1 United Kingdom 11 United States 35 Global 312
TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23671
Advantage
75
CHEMSTEP
Tel
--
Fax
--
Email
info@chemstep.com
Country
Europe
ProdList
6143
Advantage
51
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View Lastest Price from 2,5-Dichloropyrimidine manufacturers

Hebei Chuanghai Biotechnology Co,.LTD
Product
2,5-Dichloropyrimidine 22536-67-0
Price
US $9.00/KG
Min. Order
1KG
Purity
99.9
Supply Ability
1 ton
Release date
2024-08-22
R&D Scientific Inc.
Product
2,5-Dichloropyrimidine 22536-67-0
Price
US $1250.00/Kg
Min. Order
1Kg
Purity
98
Supply Ability
500 Kg
Release date
2024-04-26
Henan Fengda Chemical Co., Ltd
Product
2,5-Dichloropyrimidine 22536-67-0
Price
US $36.00-1.10/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-08

22536-67-0, 2,5-DichloropyrimidineRelated Search:

Thionyl chloride 4 6-DICHLOROPYRIMIDINE 99%,4,6-Dichloropyrimidine ,98% Sulfadiazine Dichloroethane 1,2-Dichloroethane 5-Fluorouracil Quinclorac Sodium dichloroisocyanurate 4-Amino-2,5,6-trichloropyrimidine 2,4,5,6-TETRACHLOROPYRIMIDINE 2-4-DICHLOROPYRIMIDINE CRYSTALLINE,2,4-DICHLOROPYRIMIDINE,2,4-Dichloropyrimidine, GC 97%,2,4-Dichloropyrimidine, 98+% 2-Amino-5-bromo-4,6-dichloropyrimidine 97%,2-Amino-5-bromo-4,6-dichloropyrimidine97% 2-Chloromethyl-4,6-dichloropyrimidine 5-Bromo-2,4-dichloropyrimidine ,97%,5-BROMO-2,4-DICHLOROPYRIMIDINE 99% 2,4-Dichloropyrimidine-5-carboxylic acid 5-Methyl-2,4-dichloropyrimidine Methyl 2,4-dichloropyrimidine-5-carboxylate, GC 97% 2,4,5-Trichloropyrimidine

  • 2,5-DICHLOROPYRIMIDINE
  • Pyrimidine, 2,5-dichloro- (7CI,8CI,9CI)
  • 2,5-DICHLOROPYRIMIDINE,PURITY:95% MIN(HPLC)
  • Pyrimidine, 2,5-dichloro-
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  • 2,5-DichloropyriMidine 97+%, 5-DichloropyriMidine 97+%
  • 2,5-Dichloropyrimidine 97%
  • EOS-60492
  • 2,5‐Dichloropyridimidine
  • 2,5-Dichlo
  • 2,5-DICHLOROPYRIMIDINE,PURITY
  • Macitentan Impurity 32
  • 2,5-Dichloropyrimidine&gt
  • 22536-67-0
  • 84-73-3
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  • Heterocycle-Pyrimidine series
  • Building Blocks
  • C4 to C5
  • Chemical Synthesis
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • Pyrimidines
  • Chlorinated heterocyclic series
  • PYRIMIDINE
  • Pyrimidine Series
  • Pyridines, Pyrimidines, Purines and Pteredines